Search Results - "Ge, Shealinna X."

Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein by Xu, Shan, Cherok, Edward, Das, Shweta, Li, Sunan, Roelofs, Brian A, Ge, Shealinna X, Polster, Brian M, Boyman, Liron, Lederer, W Jonathan, Wang, Chunxin, Karbowski, Mariusz

“…Ubiquitin- and proteasome-dependent outer mitochondrial membrane (OMM)-associated degradation (OMMAD) is critical for mitochondrial and cellular homeostasis…”
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Effects of Weight Loss and Aerobic Exercise Training on Adi-Pose Tissue Zinc α2-Glycoprotein and Associated Genes in Obesity by Ge, Shealinna X, Li, Guoyan, Ryan, Alice S

“…Zinc α2-glycoprotein (ZAG) has been implicated in fatty acid metabolism and utilization and is lower in obese and higher in cachexic adults compared to those…”
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The Putative Drp1 Inhibitor mdivi-1 Is a Reversible Mitochondrial Complex I Inhibitor that Modulates Reactive Oxygen Species by Bordt, Evan A., Clerc, Pascaline, Roelofs, Brian A., Saladino, Andrew J., Tretter, László, Adam-Vizi, Vera, Cherok, Edward, Khalil, Ahmed, Yadava, Nagendra, Ge, Shealinna X., Francis, T. Chase, Kennedy, Nolan W., Picton, Lora K., Kumar, Tanya, Uppuluri, Sruti, Miller, Alexandrea M., Itoh, Kie, Karbowski, Mariusz, Sesaki, Hiromi, Hill, R. Blake, Polster, Brian M.

“…Mitochondrial fission mediated by the GTPase dynamin-related protein 1 (Drp1) is an attractive drug target in numerous maladies that range from heart disease…”
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Idebenone has distinct effects on mitochondrial respiration in cortical astrocytes as compared to cortical neurons due to differential NQO1 activity by Jaber, Sausan M, Ge, Shealinna X, Milstein, Joshua L, VanRyzin, Jonathan W, Waddell, Jaylyn, Polster, Brian M

“…Idebenone is a synthetic quinone that upon reduction in cells can bypass mitochondrial Complex I defects by donating electrons to Complex III. The drug is used…”
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Low micromolar concentrations of the superoxide probe MitoSOX uncouple neural mitochondria and inhibit complex IV by Roelofs, Brian A., Ge, Shealinna X., Studlack, Paige E., Polster, Brian M.

“…MitoSOX Red is a fluorescent probe used for the detection of mitochondrial reactive oxygen species by live cell imaging. The lipophilic, positively charged…”
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Use of potentiometric fluorophores in the measurement of mitochondrial reactive oxygen species by Polster, Brian M, Nicholls, David G, Ge, Shealinna X, Roelofs, Brian A

“…Mitochondrial reactive oxygen species (ROS) are implicated in signal transduction, inflammation, neurodegenerative disorders, and normal aging. Net ROS release…”
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