Search Results - "Ge, Shan"
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CircRNA in cancer: Fundamental mechanism and clinical potential
Published in Cancer letters (01-05-2021)“…Circular RNAs (CircRNAs) are a class of single-stranded noncoding RNAs that are formed in a circular conformation via non-canonical splicing or back-splicing…”
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A brief exposure to cadmium impairs Leydig cell regeneration in the adult rat testis
Published in Scientific reports (24-07-2017)“…Cadmium is an endocrine disruptor, impairing male reproduction. The objective of this study is to investigate whether cadmium affects rat Leydig cell…”
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Research on intelligent file management system: a design strategy based on RFID technology and improved AICT algorithm
Published in PeerJ. Computer science (08-01-2024)“…In this modern era of technology and digitalization, keeping track of a manual file system in the office environment is a challenging task. This research…”
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Research on the Development of Sensor Tracking Technology under the Guidance of Artificial Intelligence
Published in MATEC Web of Conferences (2023)“…The development and application of artificial intelligence from before heavy calculation to today's parallel processing, has a qualitative leap, for the…”
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5
Long Non-coding RNAs in the Cytoplasm
Published in Genomics, proteomics & bioinformatics (01-04-2016)“…An enormous amount of long non-coding RNAs(lnc RNAs) transcribed from eukaryotic genome are important regulators in different aspects of cellular events…”
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Targetable long non-coding RNAs in cancer treatments
Published in Cancer letters (01-04-2018)“…Aberrant expression of many long non-coding RNAs has been observed in various types of cancer, implicating their crucial roles in tumorigenesis and cancer…”
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Toxicological Effects of Cadmium on Mammalian Testis
Published in Frontiers in genetics (26-05-2020)“…Cadmium is a heavy metal, and people are exposed to it through contaminated foods and smoking. In humans and other mammals, cadmium causes damage to male…”
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Insertion of an Alu element in a lncRNA leads to primate-specific modulation of alternative splicing
Published in Nature structural & molecular biology (01-11-2016)“…A primate-specific insertion of an Alu element in 5S-OT, a lncRNA transcribed from 5S rRNA loci, allows 5S-OT to regulate alternative splicing via RNA-RNA…”
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Insights into the Development of the Adult Leydig Cell Lineage from Stem Leydig Cells
Published in Frontiers in physiology (28-06-2017)“…Adult Leydig cells (ALCs) are the steroidogenic cells in the testes that produce testosterone. ALCs develop postnatally from a pool of stem cells, referred to…”
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Mitochondria Encoded Non-coding RNAs in Cell Physiology
Published in Frontiers in cell and developmental biology (30-07-2021)“…Mitochondria are the powerhouses of mammalian cells, which participate in series of metabolic processes and cellular events. Mitochondria have their own…”
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Circular RNAs in Eukaryotic Cells
Published in Current genomics (01-10-2015)“…Circular RNAs (circRNAs) are now recognized as large species of transcripts in eukaryotic cells. From model organisms such as C. elegans, Drosophila, mice to…”
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Functions of long noncoding RNAs in the nucleus
Published in Nucleus (Austin, Tex.) (25-04-2016)“…Nucleus is the residence and place of work for a plethora of long noncoding RNAs. Here, we provide a summary of the functions and functional mechanisms of…”
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The physiological function of long-noncoding RNAs
Published in Non-coding RNA research (01-12-2020)“…The physiological processes of cells and organisms are regulated by various biological macromolecules, including long-noncoding RNAs (lncRNAs), which cannot be…”
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Identification of mecciRNAs and their roles in the mitochondrial entry of proteins
Published in Science China. Life sciences (01-10-2020)“…Mammalian mitochondria have small genomes encoding very limited numbers of proteins. Over one thousand proteins and noncoding RNAs encoded by the nuclear…”
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Fibroblast growth factor homologous factor 1 stimulates Leydig cell regeneration from stem cells in male rats
Published in Journal of cellular and molecular medicine (01-08-2019)“…Fibroblast growth factor homologous factor 1 (FHF1) is an intracellular protein that does not bind to cell surface fibroblast growth factor receptor. Here, we…”
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Circular RNA circLMO1 Suppresses Cervical Cancer Growth and Metastasis by Triggering miR-4291/ ACSL4 -Mediated Ferroptosis
Published in Frontiers in oncology (07-03-2022)“…A number of studies have demonstrated that circular RNA (circRNA) plays a critical role in tumorigenesis and tumor progression. However, the biological effects…”
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Effects of bis (2‐butoxyethyl) phthalate on adrenocortical function in male rats in puberty partially via down‐regulating NR5A1/NR4A1/NR4A2 pathways
Published in Environmental toxicology (01-10-2022)“…Phthalates may interfere with the biosynthesis of steroid hormones in the adrenal cortex. Bis (2‐butoxyethyl) phthalate (BBOP) is a phthalate containing oxygen…”
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Fibroblast growth factor 16 stimulates proliferation but blocks differentiation of rat stem Leydig cells during regeneration
Published in Journal of cellular and molecular medicine (01-04-2019)“…Objectives We aim to investigate the effects of fibroblast growth factor 16 (FGF16) on Leydig cell regeneration in ethane dimethane sulphonate (EDS)‐treated…”
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Neurotrophin‐3 stimulates stem Leydig cell proliferation during regeneration in rats
Published in Journal of cellular and molecular medicine (01-12-2020)“…Neurotrophin‐3 (NT‐3) acts as an important growth factor to stimulate and control tissue development. The NT‐3 receptor, TRKC, is expressed in rat testis. Its…”
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Curcuminoid PBPD induces cuproptosis and endoplasmic reticulum stress in cervical cancer via the Notch1/RBP‐J/NRF2/FDX1 pathway
Published in Molecular carcinogenesis (01-08-2024)“…Curcumin has been shown to have antitumor properties, but its low potency and bioavailability has limited its clinical application. We designed a novel…”
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