Search Results - "Ge, R. S."

CYP2C9 polymorphism analysis in Han Chinese populations: building the largest allele frequency database by Dai, D-P, Xu, R-A, Hu, L-M, Wang, S-H, Geng, P-W, Yang, J-F, Yang, L-P, Qian, J-C, Wang, Z-S, Zhu, G-H, Zhang, X-H, Ge, R-S, Hu, G-X, Cai, J-P

“…Genetic polymorphisms of CYP2C9 significantly influence the pharmacokinetics and pharmacodynamics of some drugs, which might result in adverse drug effects and…”
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Quantitative proteomic analysis of dexamethasone-induced effects on osteoblast differentiation, proliferation, and apoptosis in MC3T3-E1 cells using SILAC by Hong, D., Chen, H.-X., Yu, H.-Q., Wang, C., Deng, H.-T., Lian, Q.-Q., Ge, R.-S.

“…Summary The impairment of osteoblast differentiation is one cause of the glucocorticoid-induced osteoporosis (GCOP). The quantitative proteomic analysis of the…”
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Self-administration of propofol is mediated by dopamine D1 receptors in nucleus accumbens in rats by Lian, Q, Wang, B, Zhou, W, Jin, S, Xu, L, Huang, Q, Lai, M, Lu, K, Tang, L, Zhu, H, Lin, H, Zhang, F, Cao, H, Li, J, Chen, J.-F, Ge, R.-S

“…Highlights ► We studied the role of dopamine receptors in the addictive property of propofol. ► Systemic D1 (not D2) receptor blockade attenuated propofol…”
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Junctophilin 3 expresses in pancreatic beta cells and is required for glucose-stimulated insulin secretion by Li, L, Pan, Z-F, Huang, X, Wu, B-W, Li, T, Kang, M-X, Ge, R-S, Hu, X-Y, Zhang, Y-H, Ge, L-J, Zhu, D-Y, Wu, Y-L, Lou, Y-J

“…It is well accepted that junctophilin (JPHs) isoforms act as a physical bridge linking plasma membrane and endoplasmic reticulum (ER) for channel crosstalk in…”
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Regulation of development of rat stem and progenitor Leydig cells by activin by Li, L., Wang, Y., Li, X., Liu, S., Wang, G., Lin, H., Zhu, Q., Guo, J., Chen, H., Ge, H.‐S., Ge, R.‐S.

“…Summary Stem Leydig cells have been demonstrated to differentiate into adult Leydig cells via intermediate stages of progenitor and immature Leydig cells…”
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Ageing effects on the diameter, nanomechanical properties and tactile perception of human hair by Tang, W., Zhang, S.G., Zhang, J.K., Chen, S., Zhu, H., Ge, S.R.

“…Background The typical changes to hair associated with ageing are greying, thinning, dryness and brittleness. Research on the influence of ageing on hair…”
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Dithiocarbamate fungicides suppress aromatase activity in human and rat aromatase activity depending on structures: 3D-QSAR analysis and molecular simulation by Ji, Z., Chen, H., Zheng, J.I., Yan, J., Lu, H., He, J., Zhu, Y., Wang, S., Li, L., Ge, R.S., Liu, Y.

“…Dithiocarbamate fungicides have been widely used in agricultural practices due to their effective control of fungal diseases, thereby contributing to global…”
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Potent inhibition of human and rat 17β-hydroxysteroid dehydrogenase 1 by curcuminoids and the metabolites: 3D QSAR and in silico docking analysis by He, J., Ji, Z., Sang, J., Quan, H., Zhang, H., Lu, H., Zheng, J., Wang, S., Ge, R.S., Li, X.

“…Curcumin, an extensively utilized natural pigment in the food industry, has attracted considerable attention due to its potential therapeutic effects, such as…”
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Resveratrol analogues and metabolites selectively inhibit human and rat 11β-hydroxysteroid dehydrogenase 1 as the therapeutic drugs: structure-activity relationship and molecular dynamics analysis by Hu, C., Zhai, Y., Lin, H., Lu, H., Zheng, J., Wen, C., Li, X., Ge, R.S., Liu, Y., Zhu, Q.

“…Resveratrol is converted to various metabolites by gut microbiota. Human and rat liver 11β-hydroxysteroid dehydrogenase 1 (11β-HSD1) are critical for…”
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Peroxisome proliferator-activated receptorβ/δ activation is essential for modulating p-Foxo1/Foxo1 status in functional insulin-positive cell differentiation by Li, L, Li, T, Zhang, Y, Pan, Z, Wu, B, Huang, X, Mei, Y, Ge, L, Shen, G, Ge, R-s, Zhu, D, Lou, Y

“…Peroxisome proliferator-activated receptors (PPARs) participate in energy homeostasis and play essential roles in diabetes therapy through their effects on…”
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Morphology and mechanical properties of polymer surfaces via scanning force microscopy by Kajiyama, T., Tanaka, K., Ge, S.-R., Takahara, A.

“…Scanning force microscopy is used in studies of the surface morphology and surface mechanical properties of polymeric solids. Several examples are presented to…”
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Effects of methoxychlor and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane on 3β-hydroxysteroid dehydrogenase and 17β-hydroxysteroid dehydrogenase-3 activities in human and rat testes by Hu, G.-X., Zhao, B., Chu, Y., Li, X.-H., Akingbemi, B. T., Zheng, Z.-Q., Ge, R. S.

“…Summary Human and rat testis microsomes were used to investigate direct inhibitory activities of methoxychlor (MXC) and its metabolite…”
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A Metabolite of Methoxychlor, 2,2-Bis(p-Hydroxyphenyl)-1,1,1-Trichloroethane, Reduces Testosterone Biosynthesis in Rat Leydig Cells Through Suppression of Steady-State Messenger Ribonucleic Acid Levels of the Cholesterol Side-Chain Cleavage Enzyme by AKINGBEMI, B. T, GE, R.-S, KLINEFELTER, G. R, GUNSALUS, G. L, HARDY, M. P

“…Postnatal development of Leydig cells involves transformation through three stages: progenitor, immature, and adult Leydig cells. The process of…”
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Variation in the end products of androgen biosynthesis and metabolism during postnatal differentiation of rat Leydig cells by Ge, R S, Hardy, M P

“…The amount of testosterone (T) secreted by Leydig cells is determined by a balance between T biosynthetic and metabolizing enzyme activities. It has been…”
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Study on the structure and wear resistance of two-step salt bath nitrocarburized steel by Qiang, Y.H., Ge, S.R., Xue, Q.J.

“…This paper deals with the investigation of two-step salt bath nitrocarburizing technologies. For comparison, ferritic nitrocarburizing was also conducted. By…”
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Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase by Hardy, D O, Ge, R S, Catterall, J F, Hou, Y T, Penning, T M, Hardy, M P

“…Dihydrotestosterone (DHT) is the most potent naturally occurring androgen, and its production in the testis may have important consequences in developmental…”
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Microstructure and tribological properties of complex nitrocarburized steel by Qiang, Y.H, Ge, S.R, Xue, Q.J

“…Two kinds of tribological apparatus were employed to investigate the friction and wear performance of steel 1045 treated by quenching plus tempering and…”
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Pharmacokinetics of anastrozole in Chinese male volunteers by Yuan, J, Wang, P Q, Ge, S R, An, F R, Shi, A G, Chen, J, Liang, J Y

“…To compare pharmacokinetics of domestic and imported tablets of anastrozole. Twenty male Chinese volunteers were enrolled in a randomized crossover study with…”
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Mono-(2-ethylhexyl) phthalate affects the steroidogenesis in rat Leydig cells through provoking ROS perturbation by Zhao, Yan, Ao, Hong, Chen, Li, Sottas, Chantal M., Ge, Ren-shan, Li, Luxi, Zhang, Yunhui

“…► We explored the effect of MEHP on androgen production of rat Leydig cells. ► Low levels of MEHP increased androgen production. ► High levels of MEHP…”
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Research on the fatigue and fracture behavior due to the fretting wear of steel wire in hoisting rope by ZHANG, D. K, GE, S. R, QIANG, Y. H

“…Hoisting steel rope is an important component of the winding equipment in coalmines. Fretting wear and its induced fatigue and fracture of wires have been the…”
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