Search Results - "Ge, Junliang"
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Computational study of novel natural agonists targeting farnesoid X receptor
Published in Scientific reports (30-07-2024)“…The farnesoid X receptor (FXR) is a crucial therapeutic target for treating non-alcoholic steatohepatitis (NASH). Although obeticholic acid (OCA) as a FXR…”
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An interrelated CataFlower enzyme system for sensitively monitoring sweat glucose
Published in Talanta (Oxford) (01-12-2021)“…An accurate measurement of sweat glucose is a promising alternative to invasive finger prick blood test, and may provide effective self-monitoring of blood…”
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Computational study on natural compounds inhibitor of c-Myc
Published in Medicine (Baltimore) (11-12-2020)“…To screen and identify ideal leading compounds from a drug library (ZINC15 database) with potential inhibition effect against c-Myc to contribute to medication…”
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Novel Gold Nanorod-Based HR1 Peptide Inhibitor for Middle East Respiratory Syndrome Coronavirus
Published in ACS applied materials & interfaces (05-06-2019)“…Middle East respiratory syndrome coronavirus (MERS-CoV) causes a severe acute respiratory syndrome-like illness with high pathogenicity and mortality due to…”
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Bioactive multi-engineered hydrogel offers simultaneous promise against antibiotic resistance and wound damage
Published in International journal of biological macromolecules (01-12-2020)“…Wound healing is a complex process involved in repairing tissue damage and preventing infection. However, there is a lack of appropriate treatment solutions…”
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Deliberative Governance as an Instrumental Mechanism: A Study of Different Types ofEnvironmental Deliberations
Published in Contemporary social sciences (Chengdu) (01-11-2020)“…Deliberative governance of environmental issues indicates that environmental governance has undergone a transformation from relying on government authority for…”
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Further Investigation About Copy Number Variations and Methylation of HADC3 in Glioma
Published in World neurosurgery (01-06-2019)Get full text
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An elegant nitroreductase responsive fluorescent probe for selective detection of pathogenic Listeria in vitro and in vivo
Published in Talanta (Oxford) (01-06-2019)“…Listeria monocytogenes (Listeria) is a facultative pathogenic bacterium, and a sensitive method for specific detection of Listeria is considered of clinically…”
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Identification of driver genes and key pathways of ependymoma
Published in Turkish neurosurgery (01-01-2024)Get full text
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Synergistic Amplification of Oxidative Stress–Mediated Antitumor Activity via Liposomal Dichloroacetic Acid and MOF‐Fe2
Published in Small (Weinheim an der Bergstrasse, Germany) (01-06-2019)“…Cancer cells are susceptible to oxidative stress; therefore, selective elevation of intracellular reactive oxygen species (ROS) is considered as an effective…”
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A sensitive and fast responsive fluorescent probe for imaging hypoxic tumors
Published in Analyst (London) (07-01-2019)“…Nitroreductase activities are positively associated with the hypoxic level of tumors, making it an attractive target for tumor detection. Herein, we have…”
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Computational study of novel natural inhibitors targeting Kirsten rat sarcoma viral oncogene homolog G12C
Published in Anti-cancer drugs (01-06-2023)“…Lung adenocarcinoma is one of the most aggressive and rapidly fatal types of malignant lung tumor. Molecular docking and virtual screening were effectively and…”
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Computational study on novel natural inhibitors targeting c-MET
Published in Medicine (Baltimore) (24-09-2021)“…This study was designed to select ideal lead compounds and preclinical drug candidates http://dict.youdao.com/w/eng/preclinical_drug_candidate/javascript:void…”
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Computational study of novel natural inhibitors targeting Kirsten rat sarcoma viral oncogene homolog G12C
Published in Anti-cancer drugs (24-02-2023)“…Lung adenocarcinoma is one of the most aggressive and rapidly fatal types of malignant lung tumor. Molecular docking and virtual screening were effectively and…”
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Selected using bioinformatics and molecular docking analyses, PHA-793887 is effective against osteosarcoma
Published in Aging (Albany, NY.) (30-06-2021)“…To identify novel prognostic and therapeutic targets for osteosarcoma patients, we compared the gene expression profiles of osteosarcoma and control tissues…”
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Novel natural inhibitors targeting B-RAF(V600E) by computational study
Published in Bioengineered (01-01-2021)“…The aim of this research was to screen the ZINC15 database to select lead compounds and drug candidates which can inhibit B-RAF (V600E). In order to identify…”
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HDAC3 Expression Correlates with the Prognosis and Grade of Patients with Glioma: A Diversification Analysis Based on Transcriptome and Clinical Evidence
Published in World neurosurgery (01-11-2018)“…This study aimed to clarify the relationship between histone deacetylase 3 (HDAC3) expression and the prognosis as well as the grade of patients with glioma…”
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Identification of novel natural inhibitors targeting AKT Serine/Threonine Kinase 1 (AKT1) by computational study
Published in Bioengineered (02-05-2022)“…Despite great progress, the current cancer treatments often have obvious toxicity and side effects. and a poor prognosis (some patients). One of the reasons…”
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Selected by gene co-expression network and molecular docking analyses, ENMD-2076 is highly effective in glioblastoma-bearing rats
Published in Aging (Albany, NY.) (09-11-2019)“…Glioblastoma is the most common type of malignant brain tumor. Bioinformatics technology and structure biology were effectively and systematically used to…”
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Computational study of novel natural inhibitors targeting aminopeptidase N(CD13)
Published in Aging (Albany, NY.) (09-05-2020)“…To screen and identify ideal leading compounds from a drug library (ZINC15 database) with potential inhibition of aminopeptidase N(CD13) to contribute to…”
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