Search Results - "Ge, Junbo"

Scientific research progress of COVID‐19/SARS‐CoV‐2 in the first five months by Li, Hua, Liu, Zhe, Ge, Junbo

“…A cluster of pneumonia (COVID‐19) cases have been found in Wuhan China in late December, 2019, and subsequently, a novel coronavirus with a positive stranded…”
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Roles of Exosomes Derived From Immune Cells in Cardiovascular Diseases by Wu, Runda, Gao, Wei, Yao, Kang, Ge, Junbo

“…Therapies aimed at minimizing adverse remodeling in cardiovascular diseases on a molecular and cellular basis are urgently needed. Exosomes are nanosized lipid…”
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Cysteine Protease Cathepsins in Atherosclerotic Cardiovascular Diseases by Wu, Hongxian, Du, Qiuna, Dai, Qiuyan, Ge, Junbo, Cheng, Xianwu

“…Atherosclerotic cardiovascular disease (ASCVD) is an inflammatory disease characterized by extensive arterial wall matrix protein degradation. Cysteine…”
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GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury by Shi, Huairui, Gao, Yang, Dong, Zhen, Yang, Ji’e, Gao, Rifeng, Li, Xiao, Zhang, Shuqi, Ma, Leilei, Sun, Xiaolei, Wang, Zeng, Zhang, Feng, Hu, Kai, Sun, Aijun, Ge, Junbo

“…[Figure: see text]…”
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Lysine acetyltransferases and lysine deacetylases as targets for cardiovascular disease by Li, Peng, Ge, Junbo, Li, Hua

“…Lysine acetylation is a conserved, reversible, post-translational protein modification regulated by lysine acetyltransferases (KATs) and lysine deacetylases…”
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Dapagliflozin in Patients with Heart Failure and Reduced Ejection Fraction by McMurray, John J.V, Solomon, Scott D, Inzucchi, Silvio E, Køber, Lars, Kosiborod, Mikhail N, Martinez, Felipe A, Ponikowski, Piotr, Sabatine, Marc S, Anand, Inder S, Bělohlávek, Jan, Böhm, Michael, Chiang, Chern-En, Chopra, Vijay K, de Boer, Rudolf A, Desai, Akshay S, Diez, Mirta, Drozdz, Jaroslaw, Dukát, Andrej, Ge, Junbo, Howlett, Jonathan G, Katova, Tzvetana, Kitakaze, Masafumi, Ljungman, Charlotta E.A, Merkely, Béla, Nicolau, Jose C, O’Meara, Eileen, Petrie, Mark C, Vinh, Pham N, Schou, Morten, Tereshchenko, Sergey, Verma, Subodh, Held, Claes, DeMets, David L, Docherty, Kieran F, Jhund, Pardeep S, Bengtsson, Olof, Sjöstrand, Mikaela, Langkilde, Anna-Maria

“…In this randomized, placebo-controlled trial, investigators evaluated the effects of the sodium–glucose cotransporter 2 inhibitor dapagliflozin in patients…”
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Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction by Solomon, Scott D, McMurray, John J.V, Anand, Inder S, Ge, Junbo, Lam, Carolyn S.P, Maggioni, Aldo P, Martinez, Felipe, Packer, Milton, Pfeffer, Marc A, Pieske, Burkert, Redfield, Margaret M, Rouleau, Jean L, van Veldhuisen, Dirk J, Zannad, Faiez, Zile, Michael R, Desai, Akshay S, Claggett, Brian, Jhund, Pardeep S, Boytsov, Sergey A, Comin-Colet, Josep, Cleland, John, Düngen, Hans-Dirk, Goncalvesova, Eva, Katova, Tzvetana, Kerr Saraiva, Jose F, Lelonek, Małgorzata, Merkely, Bela, Senni, Michele, Shah, Sanjiv J, Zhou, Jingmin, Rizkala, Adel R, Gong, Jianjian, Shi, Victor C, Lefkowitz, Martin P

“…Patients with heart failure with preserved ejection fraction were assigned to receive sacubitril–valsartan or valsartan. At a median of 35 months, there was no…”
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Interleukin-35 Promotes Macrophage Survival and Improves Wound Healing After Myocardial Infarction in Mice by Jia, Daile, Jiang, Hao, Weng, Xinyu, Wu, Jian, Bai, Peiyuan, Yang, Wenlong, Wang, Zeng, Hu, Kai, Sun, Aijun, Ge, Junbo

“…RATIONALE:Targeting inflammation has been shown to provide clinical benefit in the field of cardiovascular diseases. Although manipulating regulatory T-cell…”
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The critical roles of m6A modification in metabolic abnormality and cardiovascular diseases by Zhang, Beijian, Jiang, Hao, Dong, Zhen, Sun, Aijun, Ge, Junbo

“…N6-methyladenosine (m6A) RNA methylation is an emerging area of epigenetics, which is a reversible and dynamic modification mediating by ‘writers’ (methylase,…”
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Nanotechnology for cardiovascular diseases by Hu, Qinqin, Fang, Zheyan, Ge, Junbo, Li, Hua

“…Cardiovascular diseases have become the major killers in today's world, among which coronary artery diseases (CADs) make the greatest contributions to…”
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Extracorporeal membrane oxygenation in the treatment of respiratory failure during COVID‑19 by Ge, Junbo

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FUNDC1 protects against doxorubicin-induced cardiomyocyte PANoptosis through stabilizing mtDNA via interaction with TUFM by Bi, Yaguang, Xu, Haixia, Wang, Xiang, Zhu, Hong, Ge, Junbo, Ren, Jun, Zhang, Yingmei

“…Doxorubicin (DOX) is an effective anthracycline chemotherapeutic anticancer drug with its life-threatening cardiotoxicity severely limiting its clinical…”
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Ticagrelor in Patients with Stable Coronary Disease and Diabetes by Steg, P. Gabriel, Bhatt, Deepak L, Simon, Tabassome, Fox, Kim, Mehta, Shamir R, Harrington, Robert A, Held, Claes, Andersson, Marielle, Himmelmann, Anders, Ridderstråle, Wilhelm, Leonsson-Zachrisson, Maria, Liu, Yuyin, Opolski, Grzegorz, Zateyshchikov, Dmitry, Ge, Junbo, Nicolau, José C, Corbalán, Ramón, Cornel, Jan H, Widimský, Petr, Leiter, Lawrence A

“…Patients with stable coronary artery disease and diabetes were randomly assigned to receive either ticagrelor plus aspirin or placebo plus aspirin. At 40…”
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Initial resolution of the COVID-19 pandemic in China—can the virus return? by Ge, Junbo

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Platelet membrane-coated nanoparticle-mediated targeting delivery of Rapamycin blocks atherosclerotic plaque development and stabilizes plaque in apolipoprotein E-deficient (ApoE−/−) mice by Song, Yanan, Huang, Zheyong, Liu, Xin, Pang, Zhiqing, Chen, Jing, Yang, Hongbo, Zhang, Ning, Cao, Zhonglian, Liu, Ming, Cao, Jiatian, Li, Chenguang, Yang, Xiangdong, Gong, Hui, Qian, Juying, Ge, Junbo

“…Although certain success has been achieved in atherosclerosis treatment, tremendous challenges remain in developing more efficient strategies to treat…”
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CircUbe3a from M2 macrophage-derived small extracellular vesicles mediates myocardial fibrosis after acute myocardial infarction by Wang, Yan, Li, Chaofu, Zhao, Ranzun, Qiu, Zhimei, Shen, Changyin, Wang, Zhenglong, Liu, Weiwei, Zhang, Wei, Ge, Junbo, Shi, Bei

“…This study aimed to explore the role of circular RNAs (circRNAs) in M2 macrophage (M2M)-derived small extracellular vesicles (SEVs) in myocardial fibrosis…”
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SCN5A Variants: Association With Cardiac Disorders by Li, Wenjia, Yin, Lei, Shen, Cheng, Hu, Kai, Ge, Junbo, Sun, Aijun

“…The gene encodes the alpha subunit of the main cardiac sodium channel Na 1.5. This channel predominates inward sodium current (INa) and plays a critical role…”
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Therapeutic silencing miR-146b-5p improves cardiac remodeling in a porcine model of myocardial infarction by modulating the wound reparative phenotype by Liao, Yiteng, Li, Hao, Cao, Hao, Dong, Yun, Gao, Lei, Liu, Zhongmin, Ge, Junbo, Zhu, Hongming

“…Fibrotic remodeling is an adverse consequence of immune response-driven phenotypic modulation of cardiac cells following myocardial infarction (MI)…”
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Alpha-lipoic acid protects against pressure overload-induced heart failure via ALDH2-dependent Nrf1-FUNDC1 signaling by Li, Wenjia, Yin, Lei, Sun, Xiaolei, Wu, Jian, Dong, Zhen, Hu, Kai, Sun, Aijun, Ge, Junbo

“…Alpha-lipoic acid (α-LA), a well-known antioxidant, was proved to active ALDH2 in nitrate tolerance and diabetic animal model. However, the therapeutic…”
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Exosomal circHIPK3 Released from Hypoxia-Pretreated Cardiomyocytes Regulates Oxidative Damage in Cardiac Microvascular Endothelial Cells via the miR-29a/IGF-1 Pathway by Shi, Bei, Ge, Junbo, Long, Xianping, Rong, Jidong, Wang, Zhenglong, Liu, Weiwei, Zhao, Ranzun, Wang, Yan, Liu, Zhijiang

“…Background/Aims. Circular RNAs (circRNAs) are a class of endogenous noncoding RNAs that regulate gene expression in eukaryotes. Recently, exosomes from…”
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