Search Results - "Ge, Hong"
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Combination strategies with PD-1/PD-L1 blockade: current advances and future directions
Published in Molecular cancer (21-01-2022)“…Antibodies targeting programmed cell death protein-1 (PD-1) or its ligand PD-L1 rescue T cells from exhausted status and revive immune response against cancer…”
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Role of vacuolar-type proton ATPase in signal transduction
Published in Biochimica et biophysica acta. Bioenergetics (01-10-2015)“…The vacuolar H+-ATPase (V-ATPase) was first identified as an electrogenic proton pump that acidifies the lumen of intra- and extracellular compartments. The…”
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Estimates of Dirichlet eigenvalues for a class of sub‐elliptic operators
Published in Proceedings of the London Mathematical Society (01-06-2021)“…Let Ω be a bounded connected open subset in Rn with smooth boundary ∂Ω. Suppose that we have a system of real smooth vector fields X=(X1,X2,…,Xm) defined on a…”
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Exploring the Link between Vacuolar-Type Proton ATPase and Epithelial Cell Polarity
Published in Biological & pharmaceutical bulletin (01-10-2022)“…Vacuolar-type H+-ATPase (V-ATPase) was first identified as an electrogenic proton pump that acidifies the lumen of intracellular organelles. Subsequently, it…”
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Inferring the effectiveness of government interventions against COVID-19
Published in Science (American Association for the Advancement of Science) (19-02-2021)“…Governments are attempting to control the COVID-19 pandemic with nonpharmaceutical interventions (NPIs). However, the effectiveness of different NPIs at…”
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Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm
Published in Scientific reports (29-09-2021)“…The endocytic compartments keep their interior acidic through the inward flow of protons and anions from the cytosol. Acidification is mediated by a proton…”
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MALAT1/miR‐127‐5p Regulates Osteopontin (OPN)‐Mediated Proliferation of Human Chondrocytes Through PI3K/Akt Pathway
Published in Journal of cellular biochemistry (01-01-2018)“…ABSTRACT Osteoarthritis (OA) is characterized by progressive destruction of articular cartilage, resulting in significant disability. Chondrocytes present in…”
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Hydrogen sulfide and rhizobia synergistically regulate nitrogen (N) assimilation and remobilization during N deficiency‐induced senescence in soybean
Published in Plant, cell and environment (01-05-2020)“…Hydrogen sulfide (H2S) is emerging as an important signalling molecule that regulates plant growth and abiotic stress responses. However, the roles of H2S in…”
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Bone Pain Induced by Multiple Myeloma Is Reduced by Targeting V-ATPase and ASIC3
Published in Cancer research (Chicago, Ill.) (15-03-2017)“…Multiple myeloma patients experience severe bone pain (MMBP) that is undertreated and poorly understood. In this study, we studied MMBP in an intratibial mouse…”
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Cortical Microhemorrhage Presentation of Small Vessel Primary Angiitis of the Central Nervous System
Published in Annals of neurology (01-07-2024)“…Objective Primary angiitis of the central nervous system (PACNS) is a rare vasculitis restricted to the brain, spinal cord, and leptomeninges. This study aimed…”
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A brief exposure to cadmium impairs Leydig cell regeneration in the adult rat testis
Published in Scientific reports (24-07-2017)“…Cadmium is an endocrine disruptor, impairing male reproduction. The objective of this study is to investigate whether cadmium affects rat Leydig cell…”
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Hydrogen Sulfide Promotes Nodulation and Nitrogen Fixation in Soybean-Rhizobia Symbiotic System
Published in Molecular plant-microbe interactions (01-08-2019)“…The rhizobium-legume symbiotic system is crucial for nitrogen cycle balance in agriculture. Hydrogen sulfide (H S), a gaseous signaling molecule, may regulate…”
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Hydrogen sulfide is a crucial element of the antioxidant defense system in Glycine max–Sinorhizobium fredii symbiotic root nodules
Published in Plant and soil (01-04-2020)“…Aim H 2 S is emerging as a signaling molecule involved in the regulation of many physiological processes in plants. Here, we investigated the potential…”
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Role of the Cytosolic Domain of the a3 Subunit of V-ATPase in the Interaction with Rab7 and Secretory Lysosome Trafficking in Osteoclasts
Published in Biological & pharmaceutical bulletin (01-01-2024)“…We previously reported that the a3 subunit of proton-pumping vacuolar-type ATPase (V-ATPase) interacts with Rab7 and its guanine nucleotide exchange factor,…”
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New biorefineries and sustainable agriculture: Increased food, biofuels, and ecosystem security
Published in Renewable & sustainable energy reviews (01-07-2015)“…The sustainability revolution is the defining challenge of our time to meet increasing needs in the energy−food−water nexus without compromising the ability of…”
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Vacuolar-type ATPase: A proton pump to lysosomal trafficking
Published in Proceedings of the Japan Academy, Series B (11-06-2019)“…Vacuolar-type ATPase (V-ATPase), initially identified in yeast and plant vacuoles, pumps protons into the lumen of organelles coupled with ATP hydrolysis. The…”
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Interactions between hydrogen sulphide and rhizobia modulate the physiological and metabolism process during water deficiency‐induced oxidative defense in soybean
Published in Plant, cell and environment (01-11-2022)“…Hydrogen sulphide (H2S), a new gas signal molecule, participates in the regulation of various abiotic stresses in plants. However, how the tandem working of…”
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Impacts of heavy metals and medicinal crops on ecological systems, environmental pollution, cultivation, and production processes in China
Published in Ecotoxicology and environmental safety (01-08-2021)“…Heavy metals are widely distributed in the environment due to the natural processes and anthropogenic human activities. Their migration into no contaminated…”
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Recently developed strategies to restrain dendrite growth of Li metal anodes for rechargeable batteries
Published in Rare metals (01-06-2020)“…Lithium metal has been regarded as one of the most promising anode materials for high-energy-density batteries due to its extremely high theoretical…”
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Identification of priority areas for UGI optimisation under carbon neutrality targets: Perspectives from China
Published in Ecological indicators (01-04-2023)“…•A high-precision simulation of NPP in Wuhan was carried out based on Sentinel-2 improved CASA model.•Spatial heterogeneity mechanism of UGI carbon…”
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