Search Results - "Ge, Fei"

A drug-likeness toolbox facilitates ADMET study in drug discovery by Jia, Chen-Yang, Li, Jing-Yi, Hao, Ge-Fei, Yang, Guang-Fu

“…[Display omitted] •Online resources facilitate in silico drug-likeness study.•Databases gathering high quality and up to date data are essential for…”
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Transfer learning empowers accurate pharmacokinetics prediction of small samples by Guo, Wenbo, Dong, Yawen, Hao, Ge-Fei

“…•Transfer learning enhances PK prediction models by leveraging relevant knowledge transfer.•Transfer learning categorizes into three types based on domain and…”
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Effective removal of heavy metal ions Cd2+, Zn2+, Pb2+, Cu2+ from aqueous solution by polymer-modified magnetic nanoparticles by Ge, Fei, Li, Meng-Meng, Ye, Hui, Zhao, Bao-Xiang

“…We prepared novel Fe3O4 magnetic nanoparticles (MNPs) modified with 3-aminopropyltriethoxysilane (APS) and copolymers of acrylic acid (AA) and crotonic acid…”
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LARMD: integration of bioinformatic resources to profile ligand-driven protein dynamics with a case on the activation of estrogen receptor by Yang, Jing-Fang, Wang, Fan, Chen, Yu-Zong, Hao, Ge-Fei, Yang, Guang-Fu

“…Abstract Protein dynamics is central to all biological processes, including signal transduction, cellular regulation and biological catalysis. Among them,…”
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Roles of Phosphate Solubilizing Microorganisms from Managing Soil Phosphorus Deficiency to Mediating Biogeochemical P Cycle by Tian, Jiang, Ge, Fei, Zhang, Dayi, Deng, Songqiang, Liu, Xingwang

“…Phosphorus (P) is a vital element in biological molecules, and one of the main limiting elements for biomass production as plant-available P represents only a…”
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Future changes in precipitation extremes over Southeast Asia: insights from CMIP6 multi-model ensemble by Ge, Fei, Zhu, Shoupeng, Luo, Haolin, Zhi, Xiefei, Wang, Hao

“…Past assessments of coupled climate models have indicated that precipitation extremes are expected to intensify over Southeast Asia (SEA) under the global…”
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A review of recent studies on vortex-induced vibrations of long slender cylinders by Wu, Xiaodong, Ge, Fei, Hong, Youshi

“…This paper reviews the progress made during the past decade on vortex-induced vibration (VIV) of long slender cylindrical structures. When the aspect ratio,…”
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T cell–derived exosomes induced macrophage inflammatory protein‐1α/β drive the trafficking of CD8+ T cells in oral lichen planus by Yang, Jing‐Ya, Zhang, Jing, Lu, Rui, Tan, Ya‐Qin, Du, Ge‐Fei, Zhou, Gang

“…Oral lichen planus (OLP) is a T cell–mediated chronic inflammatory disease with uncertain aetiology. Exosomes are nanosized particles with biological…”
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Copper‐Catalyzed Oxygenative Skeletal Rearrangement of Tetrahydro‐β‐carbolines Using H2O and O2 as Oxygen Sources by Peng, Yu‐Sheng, Wang, Wei, Shi, Jun, Wu, Wei, Song, Jun‐Rong, Pan, Wei‐Dong, Hao, Ge‐Fei, Ren, Hai

“…Herein, we report an unprecedented skeletal rearrangement reaction of tetrahydro‐β‐carbolines enabled by copper‐catalyzed single‐electron oxidative…”
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Proteogenomic analysis reveals alternative splicing and translation as part of the abscisic acid response in Arabidopsis seedlings by Zhu, Fu‐Yuan, Chen, Mo‐Xian, Ye, Neng‐Hui, Shi, Lu, Ma, Kai‐Long, Yang, Jing‐Fang, Cao, Yun‐Ying, Zhang, Youjun, Yoshida, Takuya, Fernie, Alisdair R., Fan, Guang‐Yi, Wen, Bo, Zhou, Ruo, Liu, Tie‐Yuan, Fan, Tao, Gao, Bei, Zhang, Di, Hao, Ge‐Fei, Xiao, Shi, Liu, Ying‐Gao, Zhang, Jianhua

“…Summary In eukaryotes, mechanisms such as alternative splicing (AS) and alternative translation initiation (ATI) contribute to organismal protein diversity…”
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Molecular insights into the mechanism of 4‐hydroxyphenylpyruvate dioxygenase inhibition: enzyme kinetics, X‐ray crystallography and computational simulations by Lin, Hong‐Yan, Yang, Jing‐Fang, Wang, Da‐Wei, Hao, Ge‐Fei, Dong, Jiang‐Qing, Wang, Yu‐Xia, Yang, Wen‐Chao, Wu, Jia‐Wei, Zhan, Chang‐Guo, Yang, Guang‐Fu

“…Slow‐binding inhibitors with long residence time on the target often display superior efficacy in vivo. Rationally designing inhibitors with low off‐target…”
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Chemical Manipulation of Abscisic Acid Signaling: A New Approach to Abiotic and Biotic Stress Management in Agriculture by Hewage, Kamalani Achala H., Yang, Jing‐Fang, Wang, Di, Hao, Ge‐Fei, Yang, Guang‐Fu, Zhu, Jian‐Kang

“…The phytohormone abscisic acid (ABA) is the best‐known stress signaling molecule in plants. ABA protects sessile land plants from biotic and abiotic stresses…”
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Targeting Fks1 proteins for novel antifungal drug discovery by Kumar, Vinit, Huang, Juan, Dong, Yawen, Hao, Ge-Fei

“…Fks1 is a unique enzyme that makes β-1,3-glucan, a key cell wall component. Blocking Fks1 kills fungi by damaging their cell wall.Fks1 enhances fungal…”
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Emodin Inhibition of Influenza A Virus Replication and Influenza Viral Pneumonia via the Nrf2, TLR4, p38/JNK and NF-kappaB Pathways by Dai, Jian-Ping, Wang, Qian-Wen, Su, Yun, Gu, Li-Ming, Zhao, Ying, Chen, Xiao-Xua, Chen, Cheng, Li, Wei-Zhong, Wang, Ge-Fei, Li, Kang-Sheng

“…Lasting activations of toll-like receptors (TLRs), MAPK and NF-κB pathways can support influenza A virus (IAV) infection and promote pneumonia. In this study,…”
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Automated synthesis: current platforms and further needs by Wang, Zheng, Zhao, Wei, Hao, Ge-Fei, Song, Bao-An

“…[Display omitted] •Automated platforms facilitate organic synthesis study.•Software and configuration are essential for automated platforms of…”
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Protein–nucleic acid thermodynamic databases for specific uses by Mei, Long-Can, Hao, Ge-Fei, Yang, Guang-Fu

“…In response to Gromiha and Harini, we review the currently available thermodynamic databases for protein–nucleic acid interactions. These databases are…”
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Enhanced Transport Distance for Unsupervised Domain Adaptation by Li, Mengxue, Zhai, Yi-Ming, Luo, You-Wei, Ge, Peng-Fei, Ren, Chuan-Xian

“…Unsupervised domain adaptation (UDA) is a representative problem in transfer learning, which aims to improve the classification performance on an unlabeled…”
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Phylogenetic comparison of 5′ splice site determination in central spliceosomal proteins of the U1‐70K gene family, in response to developmental cues and stress conditions by Chen, Mo‐Xian, Zhang, Kai‐Lu, Gao, Bei, Yang, Jing‐Fang, Tian, Yuan, Das, Debatosh, Fan, Tao, Dai, Lei, Hao, Ge‐Fei, Yang, Guang‐Fu, Zhang, Jianhua, Zhu, Fu‐Yuan, Fang, Yan‐Ming

“…SUMMARY Intron‐containing genes have the ability to generate multiple transcript isoforms by splicing, thereby greatly expanding the eukaryotic transcriptome…”
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Preparation and Characterization of Functionalized Metal–Organic Frameworks with Core/Shell Magnetic Particles (Fe3O4@SiO2@MOFs) for Removal of Congo Red and Methylene Blue from Water Solution by Wo, Rong, Li, Qiu-Lin, Zhu, Chao, Zhang, Yan, Qiao, Ge-fei, Lei, Kai-yu, Du, Ping, Jiang, Wei

“…In this work, a novel core@double-shell three-layer structure adsorbent (Fe3O4@SiO2@Zn–TDPAT) [TDPAT = 2,4,6-tris­(3,5-dicarboxyl phenylamino)-1,3,5-triazine]…”
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FungiPAD: A Free Web Tool for Compound Property Evaluation and Fungicide-Likeness Analysis by Wang, Meng-yao, Wang, Fan, Hao, Ge-Fei, Yang, Guang-Fu

“…The increasing prevalence of fungal diseases, continual development of resistance, and stringent environmental regulations have revealed an urgent need to…”
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