Search Results - "Gdoura, Mariem"
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Development of an in-house quantitative ELISA for the evaluation of different Covid-19 vaccines in humans
Published in Scientific reports (04-07-2022)“…Reliable serological assays are needed to understand the real impact of COVID-19. In order to compare the efficiency of different COVID-19 vaccines used in the…”
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The value of West Nile virus RNA detection by real-time RT-PCR in urine samples from patients with neuroinvasive forms
Published in Archives of microbiology (01-05-2022)“…Introduction Routine laboratory screening is based on the detection of WNV specific IgM and IgG in blood and cerebrospinal fluid. Confirmation is then…”
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Dynamic of SARS-CoV-2 variants circulation in Tunisian pediatric population, during successive waves, from March 2020 to September 2022
Published in Virus research (01-06-2024)“…•This study describes the SARS-CoV-2 strains circulating in Tunisian pediatric population during successive waves.•A total of 447 complete sequences were…”
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SARS-CoV2 RT-PCR assays: In vitro comparison of 4 WHO approved protocols on clinical specimens and its implications for real laboratory practice through variant emergence
Published in Virology journal (28-03-2022)“…RT-PCR testing on nasopharyngeal swabs is a key component in the COVID-19 fighting, provided to use sensitive and specific SARS-CoV2 genome targets. In this…”
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5
Whole genome analysis of hepatitis B virus before and during long-term therapy in chronic infected patients: Molecular characterization, impact on treatment and liver disease progression
Published in Frontiers in microbiology (17-10-2022)“…Hepatitis B virus (HBV) infection remains a serious public health concern worldwide despite the availability of an efficient vaccine and the major improvements…”
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Molecular Epidemiology of SARS-CoV-2 in Tunisia (North Africa) through Several Successive Waves of COVID-19
Published in Viruses (17-03-2022)“…Documenting the circulation dynamics of SARS-CoV-2 variants in different regions of the world is crucial for monitoring virus transmission worldwide and…”
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Distribution of HCV Genotypes Among People Who Inject Drugs in Tunisia: New Evidence for Scaling Up Prevention and Treatment Toward National Elimination Goal
Published in Frontiers in microbiology (27-07-2021)“…Little is known about the distribution of hepatitis C virus (HCV) genotypes among people who inject drugs (PWID) in North African countries, including Tunisia…”
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Sequencing Using a Two-Step Strategy Reveals High Genetic Diversity in the S Gene of SARS-CoV-2 after a High-Transmission Period in Tunis, Tunisia
Published in Microbiology spectrum (22-12-2021)“…Recent efforts have reported numerous variants that influence severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral characteristics, including…”
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SARS-CoV-2 Serology: Utility and Limits of Different Antigen-Based Tests through the Evaluation and the Comparison of Four Commercial Tests
Published in Biomedicines (01-12-2022)“…Introduction: SARS-CoV-2 serology have several indications. Currently, as there are various types available, it is important to master their performance in…”
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SARS-CoV-2 excretion kinetics in nasopharyngeal and stool samples from the pediatric population
Published in Frontiers in medicine (30-10-2023)“…Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for serious respiratory infections in humans. Even in the absence of…”
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Immunogenicity and Tolerance of BNT162b2 mRNA Vaccine in Allogeneic Hematopoietic Stem Cell Transplant Patients
Published in Vaccines (Basel) (01-02-2024)“…Allogeneic hematopoietic stem cell transplantation (ASCT) induces acquired immunodeficiency, potentially altering vaccine response. Herein, we aimed to explore…”
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Humoral and Cellular Immunogenicity of Six Different Vaccines against SARS-CoV-2 in Adults: A Comparative Study in Tunisia (North Africa)
Published in Vaccines (Basel) (27-07-2022)“…Background: The mass vaccination campaign against SARS-CoV-2 was started in Tunisia on 13 March 2021 by using progressively seven different vaccines approved…”
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Immunogenicity of Mix-and-Match CoronaVac/BNT162b2 Regimen versus Homologous CoronaVac/CoronaVac Vaccination: A Single-Blinded, Randomized, Parallel Group Superiority Trial
Published in Vaccines (Basel) (01-08-2023)“…(1) Background: This study aimed to compare the immunogenicity of the mix-and-match CoronaVac/BNT162b2 vaccination to the homologous CoronaVac/CoronaVac…”
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Presumed Protective Role for Anti-Hepatitis B Virus Antibodies Against COVID-19 Severe Cases: A Clinical Study Confirming in silico Hypothesis
Published in Frontiers in medicine (08-07-2022)“…Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for COVID-19 disease which is known to have a broad clinical spectrum,…”
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The Delta variant wave in Tunisia: Genetic diversity, spatio-temporal distribution and evidence of the spread of a divergent AY.122 sub-lineage
Published in Frontiers in public health (04-01-2023)“…The Delta variant posed an increased risk to global public health and rapidly replaced the pre-existent variants worldwide. In this study, the genetic…”
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Development and evaluation of an easy to use real-time reverse-transcription loop-mediated isothermal amplification assay for clinical diagnosis of West Nile virus
Published in Journal of clinical virology (01-02-2024)“…•Developing and validation of a loop-mediated isothermal amplification for clinical diagnosis of WNV.•Amplifications on extracted viral RNA and on crude…”
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SARS-CoV2 RT-PCR assays: In vitro comparison of 4 WHO approved protocols on clinical specimens and its implications for real laboratory practice through variant emergence
Published in Virology journal (28-03-2022)“…RT-PCR testing on nasopharyngeal swabs is a key component in the COVID-19 fighting, provided to use sensitive and specific SARS-CoV2 genome targets. In this…”
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Genetic characterization of West Nile Virus strains during neuroinvasives infection outbreak in Tunisia, 2018
Published in Transboundary and emerging diseases (01-07-2021)“…West Nile Virus (WNV) is an arbovirus transmitted by mosquito bite involving birds as reservoirs, humans and equines as accidental hosts. Eight distinct…”
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Development and comparative evaluation of SARS-CoV-2 S-RBD and N based ELISA tests in various African endemic settings
Published in Diagnostic microbiology and infectious disease (01-04-2023)“…Management of the COVID-19 pandemic relies on molecular diagnostic methods supported by serological tools. Herein, we developed S-RBD- and N- based ELISA…”
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Multiplex PCR Detection of Respiratory Tract Infections in SARS-CoV-2-Negative Patients Admitted to the Emergency Department: an International Multicenter Study during the COVID-19 Pandemic
Published in Microbiology spectrum (26-10-2022)“…Respiratory tract infection (RTI) is a common cause of visits to the hospital emergency department. During the ongoing coronavirus disease 2019 (COVID-19)…”
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