Search Results - "Gazzola, Morgan"
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Unlocking the Complexity of Neuromuscular Diseases: Insights from Human Pluripotent Stem Cell-Derived Neuromuscular Junctions
Published in International journal of molecular sciences (18-10-2023)“…Over the past 20 years, the use of pluripotent stem cells to mimic the complexities of the human neuromuscular junction has received much attention…”
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Physical properties of the cytoplasm modulate the rates of microtubule polymerization and depolymerization
Published in Developmental cell (28-02-2022)“…The cytoplasm is a crowded, visco-elastic environment whose physical properties change according to physiological or developmental states. How the physical…”
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Impact of immunization against OxLDL on the pulmonary response to cigarette smoke exposure in mice
Published in Respiratory research (03-07-2018)“…Cigarette smoke exposure can affect pulmonary lipid homeostasis and cause a progressive increase in pulmonary antibodies against oxidized low-density…”
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Microtubules self-repair in living cells
Published in Current biology (09-01-2023)“…Microtubule self-repair has been studied both in vitro and in vivo as an underlying mechanism of microtubule stability. The turnover of tubulin dimers along…”
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Airway smooth muscle adapting in dynamic conditions is refractory to the bronchodilator effect of a deep inspiration
Published in American journal of physiology. Lung cellular and molecular physiology (01-02-2020)“…Airway smooth muscle (ASM) is continuously strained during breathing at tidal volume. Whether this tidal strain influences the magnitude of the bronchodilator…”
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Shortening of airway smooth muscle is modulated by prolonging the time without simulated deep inspirations in ovine tracheal strips
Published in Journal of applied physiology (1985) (01-12-2019)“…The shortening of airway smooth muscle (ASM) is greatly affected by time. This is because stimuli affecting ASM shortening, such as bronchoactive molecules or…”
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Airway smooth muscle tone increases actin filamentogenesis and contractile capacity
Published in American journal of physiology. Lung cellular and molecular physiology (01-02-2020)“…Force adaptation of airway smooth muscle (ASM) is a process whereby the presence of tone (i.e., a sustained contraction) increases the contractile capacity…”
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Repeated airway constrictions in mice do not alter respiratory function
Published in Journal of applied physiology (1985) (01-06-2018)“…It is suggested that the frequent strain the airways undergo in asthma because of repeated airway smooth muscle (ASM)-mediated constrictions contributes to…”
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The underlying physiological mechanisms whereby anticholinergics alleviate asthma
Published in Canadian journal of physiology and pharmacology (01-05-2018)“…The mechanisms whereby anticholinergics improve asthma outcomes, such as lung function, symptoms, and rate of exacerbation, can be numerous. The most obvious…”
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Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography
Published in Journal of visualized experiments (10-07-2018)“…Air volume changes created by a conscious subject breathing spontaneously within a body box are at the basis of plethysmography, a technique used to…”
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Smooth muscle in human bronchi is disposed to resist airway distension
Published in Respiratory physiology & neurobiology (15-07-2016)“…Highlights • The physiological function of airway smooth muscle still eludes us. • Studying isolated human bronchi in a dynamic setting that closely simulates…”
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Airway smooth muscle tone increases airway responsiveness in healthy young adults
Published in American journal of physiology. Lung cellular and molecular physiology (01-03-2017)“…Force adaptation, a process whereby sustained spasmogenic activation (viz., tone) of airway smooth muscle (ASM) increases its contractile capacity, has been…”
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Assessment of Respiratory Function in Conscious Mice by Double-chamber Plethysmography
Published in Journal of visualized experiments (10-07-2018)Get full text
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