Search Results - "Gazzinelli, R.T."

Butyrate induces apoptosis in murine macrophages via caspase-3, but independent of autocrine synthesis of tumor necrosis factor and nitric oxide by Ramos, M G, Rabelo, F L A, Duarte, T, Gazzinelli, R T, Alvarez-Leite, J I

“…We demonstrated that 4 mM butyrate induces apoptosis in murine peritoneal macrophages in a dose- and time-dependent manner as indicated by studies of cell…”
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Toxoplasma gondii: acquired ocular toxoplasmosis in the murine model, protective role of TNF-alpha and IFN-gamma by Gazzinelli, R T, Brézin, A, Li, Q, Nussenblatt, R B, Chan, C C

“…DNA and mRNA amplification by the polymerase chain reaction (PCR), immunohistochemical, and histopathology were performed in the eyes and brains from C57BL/6…”
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role of parasite persistence in pathogenesis of Chagas heart disease by GUTIERREZ, F.R.S, GUEDES, P.M.M, GAZZINELLI, R.T, SILVA, J.S

“…Chagas disease (CD) is caused by the infection with the protozoan haemoflagellate Trypanosoma cruzi. This disease is still a great menace to public health, and…”
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Induction of cell-mediated immunity during early stages of infection with intracellular protozoa by Gazzinelli, R T, Talvani, A, Camargo, M M, Santiago, H C, Oliveira, M A, Vieira, L Q, Martins, G A, Aliberti, J C, Silva, J S

“…Toxoplasma gondii and Trypanosoma cruzi are intracellular parasites which, as part of their life cycle, induce a potent cell-mediated immunity (CMI) maintained…”
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Cytokines as determinants of disease and disease interactions by Sher, A, Gazzinelli, R T, Jankovic, D, Scharton-Kersten, T, Yap, G, Doherty, T M, Wynn, T

“…The immune response to pathogens results in both host resistance and immunopathology. Cytokines and in particular those lymphokines produced by Th1 and Th2…”
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Application of the differential display RT-PCR strategy for the identification of inflammation-related mouse genes by Silva, A M, Pires, E G, Abrantes, E F, Ferreira, L R, Gazzinelli, R T, Reis, L F

“…The inflammatory response elicited by various stimuli such as microbial products or cytokines is determined by differences in the pattern of cellular gene…”
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Early endosome localization and activity of RasGEF1b, a toll-like receptor-inducible Ras guanine-nucleotide exchange factor by Andrade, W A, Silva, A M, Alves, V Souza, Salgado, A P C, Melo, M B, Andrade, H M, Dall'Orto, F V, Garcia, S A, Silveira, T N, Gazzinelli, R T

“…Guanine-nucleotide exchange factors (GEFs) stimulate the intrinsic GDP/GTP exchange activity of Ras and promote the formation of active Ras–GTP, which in turn…”
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Defocusing microscopy by Agero, U., Mesquita, L.G., Neves, B.R.A., Gazzinelli, R.T., Mesquita, O.N.

“…Transparent objects (phase objects) are not visible in a standard brightfield optical microscope. In order to see such objects the most used technique is…”
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Immunocytochemical identification of Leishmania and Trypanosoma cruzi amastigotes in situ with homologous and heterologous polyclonal antibodies by Barbosa, A J, da Costa, C A, Michalick, M S, Mayrink, W, Gazzinelli, R T, Tafuri, W L

“…The unlabelled antibody peroxidase-antiperoxidase method was used to study the immunocytochemical properties of Leishmania and Trypanosoma cruzi amastigotes in…”
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Chromobacterium violaceum genome: molecular mechanisms associated with pathogenicity by Brito, C.F.A. de, Carvalho, C.M.B, Santos, F.R, Gazzinelli, R.T, Oliveira, S.C, Azevedo, V, Teixeira, S.M.R

“…Chromobacterium violaceum is a versatile, Gram-negative beta-protebacterium that grows in a variety of ecosystems in tropical and subtropical areas, such as…”
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Serum levels of cytokines in patients envenomed by Tityus serrulatus scorpion sting by Magalhães, Mônica M, Pereira, Maria Elizabeth S, Amaral, Carlos F.S, Rezende, Nilton A, Campolina, Délio, Bucaretchi, Fábio, Gazzinelli, Ricardo T, Cunha-Melo, José Renan

“…Seventeen patients stung by Tityus serrulatus scorpion were classified as mild (pain at the site of the sting, n=6), moderate (local pain and one of the…”
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Biochemical characterization and protein kinase C dependency of monokine-inducing activities of Toxoplasma gondii by Grunvald, E, Chiaramonte, M, Hieny, S, Wysocka, M, Trinchieri, G, Vogel, S.N, Gazzinelli, R.T, Sher, A

“…Previous reports have indicated that the early induction of interleukin-12 (IL-12), tumor necrosis factor alpha (TNF-alpha), IL-1 beta, and IL-10 is crucial…”
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Immunocytochemical identification of leishmania and Trypanosoma cruzi amastigotes in situ with homologous and heterologous polyclonal antibodies by A.J.A. Barbosa, C.A. da Costa, M.S.M. Michalick, W. Mayrink, R.T. Gazzinelli, W.L. Tafuri

“…The unlabelled antibody peroxidase-antiperoxidase method was used to study the immunocytochemical properties of Leishmania and Trypanosoma cruzi amastigotes in…”
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CD8+ T-cell interactions with Toxoplasma gondii: implications for processing of antigen for class-I-restricted recognition by Denkers, E Y, Sher, A, Gazzinelli, R T

“…CD8+ T lymphocytes contribute to the control of acute and chronic T. gondii infection, and the activity of these cells is closely related to IFN gamma…”
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Natural anti-Gal antibodies prevent, rather than cause, autoimmunity in human Chagas' disease by Gazzinelli, R T

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Identification and characterization of protozoan products that trigger the synthesis of IL-12 by inflammatory macrophages by Gazzinelli, R T, Camargo, M M, Almeida, I C, Morita, Y S, Giraldo, M, Acosta-Serrano, A, Hieny, S, Englund, P T, Ferguson, M A, Travassos, L R, Sher, A

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Role of IL12 in MAIDS by Giese, N.A., Gazzinelli, R.T., Morawetz, R.A., Morse, H.C.

“…MAIDS is a syndrome of progressive lymphoproliferation and increasingly severe immunodeficiency that develops in mice following adult infection with retrovirus…”
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