Search Results - "Gazzard, B G"

Immune Reconstitution Inflammatory Syndrome Associated With Kaposi's Sarcoma by BOWER, M, NELSON, M, YOUNG, A. M, THIRLWELL, C, NEWSOM-DAVIS, T, MANDALIA, S, DHILLON, T, HOLMES, P, GAZZARD, B. G, STEBBING, J

“…A proportion of patients with HIV infection who subsequently receive highly active antiretroviral therapy (HAART) exhibit a deterioration in their clinical…”
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British HIV Association guidelines for the treatment of HIV‐1‐infected adults with antiretroviral therapy 2008 by Gazzard, BG

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Increased proportion of CD16+ NK cells in the colonic lamina propria of inflammatory bowel disease patients, but not after azathioprine treatment by Steel, A. W., Mela, C. M., Lindsay, J. O., Gazzard, B. G., Goodier, M. R.

“…Aliment Pharmacol Ther 2011; 33: 115–126 Summary Background  Distinct functional subsets of natural killer cells potentially contribute to the pathology of…”
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A 48-Week, Randomized, Open-Label Comparison of Three Abacavir-Based Substitution Approaches in the Management of Dyslipidemia and Peripheral Lipoatrophy by Moyle, G J, Baldwin, C, Langroudi, B, Mandalia, S, Gazzard, B G

“…BACKGROUND:The mechanisms by which dyslipidemia and lipoatrophy develop during antiretroviral therapy are not clear. No treatment of lipoatrophy is currently…”
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The value of anal cytology and human papillomavirus typing in the detection of anal intraepithelial neoplasia: a review of cases from an anoscopy clinic by Fox, P A, Seet, J E, Stebbing, J, Francis, N, Barton, S E, Strauss, S, Allen-Mersh, T G, Gazzard, B G, Bower, M

“…Background: Previous studies have reached differing conclusions about the utility of anal cytology as a screening tool for anal intraepithelial neoplasia…”
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Antiretroviral Therapy in Adults: Updated Recommendations of the International AIDS Society–USA Panel by Carpenter, Charles C. J, Cooper, David A, Fischl, Margaret A, Gatell, Jose M, Gazzard, Brian G, Hammer, Scott M, Hirsch, Martin S, Jacobsen, Donna M, Katzenstein, David A, Montaner, Julio S. G, Richman, Douglas D, Saag, Michael S, Schechter, Mauro, Schooley, Robert T, Thompson, Melanie A, Vella, Stefano, Yeni, Patrick G, Volberding, Paul A

“…OBJECTIVE To update recommendations for antiretroviral therapy for adult human immunodeficiency virus type 1 (HIV-1) infection, based on new information and…”
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The Changing Pattern of AIDS-defining Illnesses with the Introduction of Highly Active Antiretroviral Therapy (HAART)in a London Clinic by Ives, N.J., Gazzard, B.G., Easterbrook, P.J.

“…Objectives:To quantify the progressive impact of combination antiretroviral therapy (ART) on the incidence of AIDS-defining illnesses (ADIs) over a 9-year…”
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Switching from twice‐daily abacavir and lamivudine to the once‐daily fixed‐dose combination tablet of abacavir and lamivudine improves patient adherence and satisfaction with therapy by Maitland, D, Jackson, A, Osorio, J, Mandalia, S, Gazzard, BG, Moyle, GJ

“…Background Patients prefer fewer pills and once‐daily (qd) dosing without food restrictions. We assessed the impact on adherence [by Medication Event…”
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Paclitaxel for anthracycline-resistant AIDS-related Kaposi’s sarcoma: clinical and angiogenic correlations by Stebbing, J., Wildfire, A., Portsmouth, S., Powles, T., Thirlwell, C., Hewitt, P., Nelson, M., Patterson, S., Mandalia, S., Gotch, F., Gazzard, B. G., Bower, M.

“…Background: Murine data indicate that angiogenesis is central to the aetiopathogenesis of Kaposi’s sarcoma (KS). Therefore, we measured angiogenic cytokines…”
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Pancreatic insufficiency in patients with HIV infection: role of didanosine questioned by Martin, TCS, Scourfield, A, Rockwood, N, Martin, NK, Patel, N, Nelson, M, Gazzard, BG

“…Objectives The aim of the study was to identify possible causes of pancreatic insufficiency in patients with HIV infection. Methods A retrospective analysis of…”
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A Compartmental Pharmacokinetic Evaluation of Long-Acting Rilpivirine in HIV-Negative Volunteers for Pre-Exposure Prophylaxis by Jackson, A G A, Else, L J, Mesquita, P M M, Egan, D, Back, D J, Karolia, Z, Ringner-Nackter, L, Higgs, C J, Herold, B C, Gazzard, B G, Boffito, M

“…Rilpivirine long‐acting (RPV‐LA) is a parenteral formulation enabling prolonged plasma exposure. We explored its multiple‐compartment pharmacokinetics (PK)…”
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Better maintained adherence on switching from twice‐daily to once‐daily therapy for HIV: a 24‐week randomized trial of treatment simplification using stavudine prolonged‐release capsules by Portsmouth, SD, Osorio, J, McCormick, K, Gazzard, BG, Moyle, GJ

“…Background Adherence to antiretroviral therapy is critical to treatment outcomes. Adherence studies in other therapeutic areas of medicine suggest that…”
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Itraconazole solution: higher serum drug concentrations and better clinical response rates than the capsule formulation in acquired immunodeficiency syndrome patients with candidosis by Cartledge, J D, Midgely, J, Gazzard, B G

“…AIMS: To compare the serum concentrations of itraconazole and hydroxyitraconazole after treatment with itraconazole cyclodextrin solution and itraconazole…”
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Reasons for non-adherence to antiretroviral therapy: Patients' perspectives provide evidence of multiple causes by Walsh, J. C., Horne, R., Dalton, M., Burgess, A. P., Gazzard, B. G.

“…The objective of the study was to define common reasons for non-adherence (NA) to highly active antiretroviral therapy (HAART) and the number of reasons…”
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British HIV Association and Children's HIV Association position statement on infant feeding in the UK 2011 by Taylor, GP, Anderson, J, Clayden, P, Gazzard, BG, Fortin, J, Kennedy, J, Lazarus, L, Newell, M‐L, Osoro, B, Sellers, S, Tookey, PA, Tudor‐Williams, G, Williams, A

“…To prevent the transmission of HIV infection during the postpartum period, the British HIV Association and Children's HIV Association (BHIVA/CHIVA) continue to…”
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Investigation of chronic diarrhoea in acquired immunodeficiency syndrome. A prospective study of 155 patients by Blanshard, C, Francis, N, Gazzard, B G

“…BACKGROUND AND AIMS: The optimum diagnostic investigation for patients with acquired immunodeficiency syndrome (AIDS) and diarrhoea is not known. Often no…”
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Immunological and virological consequences of patient‐directed antiretroviral therapy interruption during chronic HIV‐1 infection by Burton, C. T., Nelson, M. R., Hay, P., Gazzard, B. G., Gotch, F. M., Imami, N.

“…Summary Increasing numbers of patients are choosing to interrupt highly active antiretroviral therapy (HAART). We describe the effect of patient‐directed…”
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Intestinal absorptive capacity, intestinal permeability and jejunal histology in HIV and their relation to diarrhoea by Keating, J, Bjarnason, I, Somasundaram, S, Macpherson, A, Francis, N, Price, A B, Sharpstone, D, Smithson, J, Menzies, I S, Gazzard, B G

“…Intestinal function is poorly defined in patients with HIV infection. Absorptive capacity and intestinal permeability were assessed using 3-O-methyl-D-glucose,…”
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Impact of antiretroviral choice on hypercholesterolaemia events: the role of the nucleoside reverse transcriptase inhibitor backbone by Jones, R, Sawleshwarkar, S, Michailidis, C, Jackson, A, Mandalia, S, Stebbing, J, Bower, M, Nelson, M, Gazzard, BG, Moyle, GJ

“…Background The use of highly active antiretroviral therapy (HAART) has profoundly altered the life expectancy of individuals infected with HIV. Metabolic…”
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Reconstitution of CD4+ T cell responses in HIV‐1 infected individuals initiating highly active antiretroviral therapy (HAART) is associated with renewed interleukin‐2 production and responsiveness by HARDY, G. A. D., IMAMI, N., SULLIVAN, A. K., PIRES, A., BURTON, C. T., NELSON, M. R., GAZZARD, B. G., GOTCH, F. M.

“…SUMMARY Reconstitution of functional CD4+ T cell responsiveness to in vitro stimuli is associated with continuous highly active antiretroviral therapy (HAART)…”
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