Search Results - "Gazzaniga, Francesca S."

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    Symbionts exploit complex signaling to educate the immune system by Erturk-Hasdemir, Deniz, Oh, Sungwhan F., Okan, Nihal A., Stefanetti, Giuseppe, Gazzaniga, Francesca S., Seeberger, Peter H., Plevy, Scott E., Kasper, Dennis L.

    “…The mammalian immune system is tolerized to trillions of microbes residing on bodily surfaces and can discriminate between symbionts and pathogens despite…”
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    The Major Reverse Transcriptase―Incompetent Splice Variant of the Human Telomerase Protein Inhibits Telomerase Activity but Protects from Apoptosis by LISTERMAN, Imke, JIE SUN, GAZZANIGA, Francesca S, LUKAS, Jason L, BLACKBURN, Elizabeth H

    Published in Cancer research (Chicago, Ill.) (01-05-2013)
    “…Human telomerase reverse transcriptase (hTERT; the catalytic protein subunit of telomerase) is subjected to numerous alternative splicing events, but the…”
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    Microbiota-dependent regulation of costimulatory and coinhibitory pathways via innate immune sensors and implications for immunotherapy by Park, Joon Seok, Gazzaniga, Francesca S., Kasper, Dennis L., Sharpe, Arlene H.

    Published in Experimental & molecular medicine (01-09-2023)
    “…Our bodies are inhabited by trillions of microorganisms. The host immune system constantly interacts with the microbiota in barrier organs, including the…”
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    An Investigation of the Effects of the Core Protein Telomerase Reverse Transcriptase on Wnt Signaling in Breast Cancer Cells by Listerman, Imke, Gazzaniga, Francesca S., Blackburn, Elizabeth H.

    Published in Molecular and Cellular Biology (01-01-2014)
    “…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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    Harnessing Colon Chip Technology to Identify Commensal Bacteria That Promote Host Tolerance to Infection by Gazzaniga, Francesca S, Camacho, Diogo M, Wu, Meng, Silva Palazzo, Matheus F, Dinis, Alexandre L M, Grafton, Francis N, Cartwright, Mark J, Super, Michael, Kasper, Dennis L, Ingber, Donald E

    “…Commensal bacteria within the gut microbiome contribute to development of host tolerance to infection, however, identifying specific microbes responsible for…”
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    Sharing the load in NAD metabolism by Gazzaniga, Francesca S.

    Published in Cell host & microbe (14-12-2022)
    “…Recently in Cell Metabolism, Challapa et al. used isotope labeling to track NAD metabolism in host tissues and the gut microbiota. They describe a symbiotic…”
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    An antiapoptotic role for telomerase RNA in human immune cells independent of telomere integrity or telomerase enzymatic activity by Gazzaniga, Francesca S., Blackburn, Elizabeth H.

    Published in Blood (11-12-2014)
    “…Telomerase is a ribonucleoprotein complex that adds telomeric DNA to the ends of linear chromosomes. It contains two core canonical components: the essential…”
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    Targeting PD-L2–RGMb overcomes microbiome-related immunotherapy resistance by Park, Joon Seok, Gazzaniga, Francesca S., Wu, Meng, Luthens, Amalia K., Gillis, Jacob, Zheng, Wen, LaFleur, Martin W., Johnson, Sarah B., Morad, Golnaz, Park, Elizabeth M., Zhou, Yifan, Watowich, Stephanie S., Wargo, Jennifer A., Freeman, Gordon J., Kasper, Dennis L., Sharpe, Arlene H.

    Published in Nature (London) (11-05-2023)
    “…The gut microbiota is a crucial regulator of anti-tumour immunity during immune checkpoint inhibitor therapy. Several bacteria that promote an anti-tumour…”
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    Gut microbial fatty acid isomerization modulates intraepithelial T cells by Song, Xinyang, Zhang, Haohao, Zhang, Yanbo, Goh, Byoungsook, Bao, Bin, Mello, Suelen S., Sun, Ximei, Zheng, Wen, Gazzaniga, Francesca S., Wu, Meng, Qu, Fangfang, Yin, Qiangzong, Gilmore, Michael S., Oh, Sungwhan F., Kasper, Dennis L.

    Published in Nature (London) (27-07-2023)
    “…The human gut microbiome constantly converts natural products derived from the host and diet into numerous bioactive metabolites 1 – 3 . Dietary fats are…”
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    Microbial transmission in the social microbiome and host health and disease by Sarkar, Amar, McInroy, Cameron J A, Harty, Siobhán, Raulo, Aura, Ibata, Neil G O, Valles-Colomer, Mireia, Johnson, Katerina V-A, Brito, Ilana L, Henrich, Joseph, Archie, Elizabeth A, Barreiro, Luis B, Gazzaniga, Francesca S, Finlay, B Brett, Koonin, Eugene V, Carmody, Rachel N, Moeller, Andrew H

    Published in Cell (04-01-2024)
    “…Although social interactions are known to drive pathogen transmission, the contributions of socially transmissible host-associated mutualists and commensals to…”
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    Establishment of a Modular Anaerobic Human Intestine Chip by Jalili-Firoozinezhad, Sasan, Bein, Amir, Gazzaniga, Francesca S, Fadel, Cicely W, Novak, Richard, Ingber, Donald E

    “…It is impossible to analyze human-specific host-microbiome interactions using animal models and existing in vitro methods fail to support survival of human…”
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    Veggies and Intact Grains a Day Keep the Pathogens Away by Gazzaniga, Francesca S., Kasper, Dennis L.

    Published in Cell (17-11-2016)
    “…In this issue of Cell, Desai et al. compare how dietary fiber affects the gut microbiota and susceptibility to disease. They find that a fiber-free diet…”
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    Wild gut microbiota protects from disease by Gazzaniga, Francesca S, Kasper, Dennis L

    Published in Cell research (01-02-2018)
    “…Wild mice are genetically similar to laboratory mice, but have a distinct gut microbiota that protects from disease. There is no doubt that the trillions of…”
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    Heterogeneous dysregulation of microRNAs across the autism spectrum by Abu-Elneel, Kawther, Liu, Tsunglin, Gazzaniga, Francesca S., Nishimura, Yuhei, Wall, Dennis P., Geschwind, Daniel H., Lao, Kaiqin, Kosik, Kenneth S.

    Published in Neurogenetics (01-07-2008)
    “…microRNAs (miRNAs) are ~21 nt transcripts capable of regulating the expression of many mRNAs and are abundant in the brain. miRNAs have a role in several…”
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    Abstract A58: Wnt signaling pathway components are associated with telomerase activity in breast cancer by Listerman, Imke, Gazzaniga, Francesca S., Heiser, Laura M., Lukas, Jason J., Goldstein, Ted, Haussler, David, Gray, Joe W., Blackburn, Elizabeth H.

    Published in Cancer research (Chicago, Ill.) (15-09-2011)
    “…Abstract Telomerase is a ribonucleoprotein complex that adds TTAGGG repeats to telomeres in a highly regulated fashion. Telomerase activity is absent in normal…”
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