Search Results - "Gaymon, Avery"

CRISPR-engineered T cells in patients with refractory cancer by Stadtmauer, Edward A, Fraietta, Joseph A, Davis, Megan M, Cohen, Adam D, Weber, Kristy L, Lancaster, Eric, Mangan, Patricia A, Kulikovskaya, Irina, Gupta, Minnal, Chen, Fang, Tian, Lifeng, Gonzalez, Vanessa E, Xu, Jun, Jung, In-Young, Melenhorst, J Joseph, Plesa, Gabriela, Shea, Joanne, Matlawski, Tina, Cervini, Amanda, Gaymon, Avery L, Desjardins, Stephanie, Lamontagne, Anne, Salas-Mckee, January, Fesnak, Andrew, Siegel, Donald L, Levine, Bruce L, Jadlowsky, Julie K, Young, Regina M, Chew, Anne, Hwang, Wei-Ting, Hexner, Elizabeth O, Carreno, Beatriz M, Nobles, Christopher L, Bushman, Frederic D, Parker, Kevin R, Qi, Yanyan, Satpathy, Ansuman T, Chang, Howard Y, Zhao, Yangbing, Lacey, Simon F, June, Carl H

“…CRISPR-Cas9 gene editing provides a powerful tool to enhance the natural ability of human T cells to fight cancer. We report a first-in-human phase 1 clinical…”
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Cytokine-mediated CAR T therapy resistance in AML by Bhagwat, Anand S, Torres, Leonel, Shestova, Olga, Shestov, Maksim, Mellors, Patrick W, Fisher, Han R, Farooki, Saamia N, Frost, Benjamin F, Loken, Michael R, Gaymon, Avery L, Frazee, Diane, Rogal, Walter, Frey, Noelle, Hexner, Elizabeth O, Luger, Selina M, Loren, Alison W, Martin, Mary Ellen, McCurdy, Shannon R, Perl, Alexander E, Stadtmauer, Edward A, Brogdon, Jennifer L, Fraietta, Joseph A, Hwang, Wei-Ting, Siegel, Don L, Plesa, Gabriela, Aplenc, Richard, Porter, David L, June, Carl H, Gill, Saar I

“…Acute myeloid leukemia (AML) is a rapidly progressive malignancy without effective therapies for refractory disease. So far, chimeric antigen receptor (CAR) T…”
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Anti-CD19 CAR T cells in combination with ibrutinib for the treatment of chronic lymphocytic leukemia by Gill, Saar, Vides, Vanessa, Frey, Noelle V., Hexner, Elizabeth O., Metzger, Susan, O'Brien, Megan, Hwang, Wei-Ting, Brogdon, Jennifer L., Davis, Megan M., Fraietta, Joseph A., Gaymon, Avery L., Gladney, Whitney L., Lacey, Simon F., Lamontagne, Anne, Mato, Anthony R., Maus, Marcela V., Melenhorst, J. Joseph, Pequignot, Edward, Ruella, Marco, Shestov, Maksim, Byrd, John C., Schuster, Stephen J., Siegel, Donald L., Levine, Bruce L., June, Carl H., Porter, David L.

“…•Autologous CART-19 can be safely added to ibrutinib.•Addition of CART-19 to ibrutinib leads to frequent, durable, and deep remissions in CLL. [Display…”
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A phase I trial of cyclosporine for hospitalized patients with COVID-19 by Blumberg, Emily A, Noll, Julia Han, Tebas, Pablo, Fraietta, Joseph A, Frank, Ian, Marshall, Amy, Chew, Anne, Veloso, Elizabeth A, Carulli, Alison, Rogal, Walter, Gaymon, Avery L, Schmidt, Aliza H, Barnette, Tiffany, Jurek, Renee, Martins, Rene, Hudson, Briana M, Chavda, Kalyan, Bailey, Christina M, Church, Sarah E, Noorchashm, Hooman, Hwang, Wei-Ting, June, Carl H, Hexner, Elizabeth O

“…BACKGROUNDCOVID-19 remains a global health emergency with limited treatment options, lagging vaccine rates, and inadequate healthcare resources in the face of…”
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Long-Term Outcomes From a Randomized Dose Optimization Study of Chimeric Antigen Receptor Modified T Cells in Relapsed Chronic Lymphocytic Leukemia by Frey, Noelle V, Gill, Saar, Hexner, Elizabeth O, Schuster, Stephen, Nasta, Sunita, Loren, Alison, Svoboda, Jakub, Stadtmauer, Edward, Landsburg, Daniel J, Mato, Anthony, Levine, Bruce L, Lacey, Simon F, Melenhorst, Jan Joseph, Veloso, Elizabeth, Gaymon, Avery, Pequignot, Edward, Shan, Xinhe, Hwang, Wei-Ting, June, Carl H, Porter, David L

“…To describe long-term outcomes of anti-CD19 chimeric antigen receptor T (CART) cells in patients with relapsed or refractory chronic lymphocytic leukemia…”
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First-in-Human Assessment of Feasibility and Safety of Multiplexed Genetic Engineering of Autologous T Cells Expressing NY-ESO -1 TCR and CRISPR/Cas9 Gene Edited to Eliminate Endogenous TCR and PD-1 (NYCE T cells) in Advanced Multiple Myeloma (MM) and Sarcoma by Stadtmauer, Edward A., Cohen, Adam D., Weber, Kristy, Lacey, Simon F, Gonzalez, Vanessa E., Melenhorst, J. Joseph, Fraietta, Joseph A, Plesa, Gabriela, Shea, Joanne, Matlawski, Tina, Cervini, Amanda, Mangan, Patricia, Gaymon, Avery, Desjardins, Stephanie, Lancaster, Eric, Salas-Mckee, January, Suhoski, Megan M., Fesnak, Andrew, O'Rourke, Matthew, Lamontagne, Anne, Siegel, Don L., Young, Regina M, Chew, Anne, Nobles, Christopher L, Bushman, Frederic D., Chang, Howard Y., Satpathy, Ansuman T., Zhao, Yangbing, Hwang, Wei-Ting, Hexner, Elizabeth O., June, Carl H

“…Background: Autologous T cells genetically modified with a lentiviral vector to express affinity-enhanced T cell receptors (TCR) or chimeric antigen receptors…”
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