Search Results - "Gaydos, L."

Loose-coupling a cellular automaton model and GIS: long-term urban growth prediction for San Francisco and Washington/Baltimore by CLARKE, KEITH C., GAYDOS, LEONARD J.

“…Prior research developed a cellular automaton model, that was calibrated by using historical digital maps of urban areas and can be used to predict the future…”
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Driver trust in and training for advanced driver assistance systems in Real-World driving by Lubkowski, Steven D., Lewis, Bridget A., Gawron, Valerie J., Gaydos, Travis L., Campbell, Keith C., Kirkpatrick, Shelley A., Reagan, Ian J., Cicchino, Jessica B.

“…•Ratings of trust in ADAS technologies increased with length of ownership.•Just under half of participants reported experiencing unexpected ADAS…”
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Markers of bone resorption in patients treated with pamidronate by Lipton, A., Demers, L., Curley, E., Chinchilli, V., Gaydos, L., Hortobagyi, G., Theriault, R., Clemens, D., Costa, L., Seaman, J., Knight, R.

“…Pyridinoline (PYD), deoxypyridinoline (DPD), and N-telopeptide (NTX) are markers of bone resorption. In cancer patients with bone metastases, NTX is more often…”
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Measured variability and uncertainty in flight operations by Gaydos, Travis L, Kirkman, Worth, Shresta, Sanjiv, Blair, Eric, Kuchenbrod, John

“…Presents a collection of slides from the author's conference presentation. * Our model provides the flexibility to estimate uncertainty of several TBO…”
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Perspectives on Some Controversies in Cardiovascular Disease Risk Assessment in the Pharmaceutical Development of Glucose-Lowering Medications by Hoogwerf, Byron J, Manner, David H, Fu, Haoda, Moscarelli, Elena, Gaydos, Brenda L, Heine, Robert J

“…The U.S. Food and Drug Administration (FDA) issued guidance on requirements to assess cardiovascular disease (CVD) risk with drugs being developed for approval…”
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Dose-finding results in an adaptive, seamless, randomized trial of once-weekly dulaglutide combined with metformin in type 2 diabetes patients (AWARD-5) by Skrivanek, Z., Gaydos, B. L., Chien, J. Y., Geiger, M. J., Heathman, M. A., Berry, S., Anderson, J. H., Forst, T., Milicevic, Z., Berry, D.

“…Aims AWARD‐5 was an adaptive, seamless, double‐blind study comparing dulaglutide, a once‐weekly glucagon‐like peptide‐1 (GLP‐1) receptor agonist, with placebo…”
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Neuropsychological Test Performance in Healthy Volunteers Before and After Donepezil Administration by Beglinger, Leigh J., Gaydos, Brenda L., Kareken, David A., Tangphao-Daniels, Oranee, Siemers, Eric R., Mohs, Richard C.

“…Participants in early Phase I clinical trials for drugs designed to enhance cognition are typically healthy volunteers. If improvement can be detected with a…”
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Use of 0.3% triclosan (Bacti-Stat) to eradicate an outbreak of methicillin-resistant Staphylococcus aureus in a neonatal nursery by Zafar, A.B., Butler, R.C., Reese, D.J., Gaydos, L.A., Mennonna, P.A.

“…Background: Once established in an institution, methicillin-resistant Staphylococcus aureus (MRSA) outbreaks have proved difficult to eradicate, despite…”
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Effectiveness of infection control program in controlling nosocomial Clostridium difficile by Zafar, Abdul B., Gaydos, Larry A., Furlong, William B., Nguyen, Michelle H., Mennonna, Patricia A.

“…Objective: To report the effectiveness of use of comprehensive infection control measures to reduce the incidence of Clostridium difficile (CD) in an…”
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A clinical utility index for selecting an optimal insulin dosing algorithm for LY2605541 in patients with type 2 diabetes pretreated with basal insulin by Manner, David H, Luo, Junxiang, Qu, Yongming, Berry, Scott, Gaydos, Brenda L, Jacober, Scott J

“…Because insulin dosing requires optimization of glycemic control, it is important to use a single metric of benefit and risk to determine best insulin dosing…”
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Dependence and Reversal of Nitric Oxide Production on NF-κ-B in Silica and Lipopolysaccharide Induced Macrophages by Chen, F., Kuhn, D.C., Sun, S.C., Gaydos, L.J., Demers, L.M.

“…In this report the differential regulation of NF-κB and nitric oxide (NO) was investigated in the mouse macrophage cell line RAW 264.7 following exposure to a…”
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VISUALIZING GENETIC CONSTRAINTS by Gaydos, Travis L., Heckman, Nancy E., Kirkpatrick, Mark, Stinchcombe, J. R., Schmitt, Johanna, Kingsolver, Joel, Marron, J. S.

“…Principal Components Analysis (PCA) is a common way to study the sources of variation in a high-dimensional data set. Typically, the leading principal…”
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Induction of nitric oxide and nitric oxide synthase mRNA by silica and lipopolysaccharide in PMA-primed THP-1 cells by Chen, F, Kuhn, D C, Gaydos, L J, Demers, L M

“…Nitric oxide (NO), a nitrogen-free radical, plays an important role in mediating inflammatory reaction and cytotoxicity of tissue. To determine whether NO was…”
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Effect of a Comprehensive Program to Reduce Needlestick Injuries by Zafar, Abdul B., Butler, R. Christopher, Podgorny, Judith M., Mennonna, Patricia A., Gaydos, Larry A., Sandiford, John A.

“…The Arlington Hospital Needlestick Injury (NSI) Prevention Program was created to protect healthcare workers from NSI and to assess the effectiveness of our…”
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Essential Role of NF-κB Activation in Silica-Induced Inflammatory Mediator Production in Macrophages by Chen, F., Sun, S.C., Kuh, D.C., Gaydos, L.J., Demers, L.M.

“…In this report, we demonstrate that NF-κB, a ubiquitous transcription factor, plays an essential role in silica-induced inflammatory mediator production in the…”
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Tetrandrine Inhibits Signal-Induced NF-κB Activation in Rat Alveolar Macrophages by Chen, Fei, Sun, Shaocong, Kuhn, Douglas C., Lu, Yongju, Gaydos, Lesley J., Shi, Xianglin, Demers, Laurence M.

“…Tetrandrine is a bisbenzylisoquinoline alkaloid isolated from a natural Chinese herbal medicine. While this alkaloid has been shown to exhibit antifibrotic and…”
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Involvement of NF-kappaB in silica-induced cyclooxygenase II gene expression in rat alveolar macrophages by Chen, F, Sun, S, Kuhn, D C, Gaydos, L J, Shi, X, Lu, Y, Demers, L M

“…The role of nuclear factor (NF)-kappaB transcription factor in silica-induced cyclooxygenase (COX) II gene expression was examined in the rat alveolar…”
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An inhibitor of thromboxane production attenuates tumor necrosis factor release by activated human alveolar macrophages by Kuhn, D C, Stauffer, J L, Gaydos, L J, Lacey, S L, Demers, L M

“…Tumor necrosis factor alpha (TNF alpha) and thromboxane A2 (TXA2) are major products of the activated alveolar macrophage and serve as key mediators of lung…”
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Flexible schedules for managers by Gaydos, L S, Ritter, M G

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Reliability and Validity Testing of the CDC Worksite Health ScoreCard: An Assessment Tool to Help Employers Prevent Heart Disease, Stroke, and Related Health Conditions by Roemer, Enid Chung, Kent, Karen B., Samoly, Daniel K., Gaydos, Laura M., Smith, Kristyn J., Agarwal, Amol, Matson-Koffman, Dyann M., Goetzel, Ron Z.

“…OBJECTIVE:To develop, evaluate, and improve the reliability and validity of the CDC Worksite Health ScoreCard (HSC). METHODS:We tested interrater reliability…”
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