Search Results - "Gaya, Anna"

Persistent replication of SARS-CoV-2 in a severely immunocompromised patient treated with several courses of remdesivir by Camprubí, Daniel, Gaya, Anna, Marcos, Maria Angeles, Martí-Soler, Helena, Soriano, Alex, Mosquera, Maria del Mar, Oliver, Aina, Santos, Marta, Muñoz, Jose, García-Vidal, Carol

“…•Clinical and microbiological response of SARS-CoV-2 to remdesivir in immunocompromised patients has not been fully evaluated.•Persistent viral replication…”
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Patient preferences and quality of life implications of ravulizumab (every 8 weeks) and eculizumab (every 2 weeks) for the treatment of paroxysmal nocturnal hemoglobinuria by Peipert, John Devin, Kulasekararaj, Austin G., Gaya, Anna, Langemeijer, Saskia M. C., Yount, Susan, Gonzalez-Fernandez, F. Ataulfo, Ojeda Gutierrez, Emilio, Martens, Christa, Sparling, Amy, Webster, Kimberly A., Cella, David, Tomazos, Ioannis, Ogawa, Masayo, Piatek, Caroline I., Wells, Richard, Sicre de Fontbrune, Flore, Röth, Alexander, Mitchell, Lindsay, Hill, Anita, Kaiser, Karen

“…Background Eculizumab has transformed management of paroxysmal nocturnal hemoglobinuria (PNH) since its approval. However, its biweekly dosing regimen remains…”
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Prolonged viral replication in patients with hematologic malignancies hospitalized with COVID-19 by Garcia-Vidal, Carolina, Puerta-Alcalde, Pedro, Mateu, Aina, Cuesta-Chasco, Genoveva, Meira, Fernanda, Lopera, Carlos, Monzo, Patricia, Santos-Bravo, Marta, Duenas, Gerard, Chumbita, Mariana, Garcia-Pouton, Nicole, Gaya, Anna, Bodro, Marta, Herrera, Sabina, Mosquera, Mar, Fernandez-Aviles, Francesc, Martinez, Jose Antonio, Mensa, Josep, Gine, Eva, Marcos, Maria Angeles, Soriano, Alex

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Regulation of JAK2 by miR-135a: prognostic impact in classic Hodgkin lymphoma by Navarro, Alfons, Diaz, Tania, Martinez, Antonio, Gaya, Anna, Pons, Aina, Gel, Bernat, Codony, Carles, Ferrer, Gerardo, Martinez, Carmen, Montserrat, Emili, Monzo, Mariano

“…The behavior of classic Hodgkin lymphoma (cHL) is determined by both the intrinsic features of the tumor cells and the characteristics of the microenvironment,…”
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Efficacy and tolerability of hydroxyurea in the treatment of the hyperproliferative manifestations of myelofibrosis: results in 40 patients by Martínez-Trillos, Alejandra, Gaya, Anna, Maffioli, Margherita, Arellano-Rodrigo, Eduardo, Calvo, Xavier, Díaz-Beyá, Marina, Cervantes, Francisco

“…Hydroxyurea (HU) is frequently given as treatment for myelofibrosis (MF), but data on its efficacy and tolerability are scarce. The results of HU therapy were…”
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MicroRNA expression profiling in classic Hodgkin lymphoma by Navarro, Alfons, Gaya, Anna, Martinez, Antonio, Urbano-Ispizua, Alvaro, Pons, Aina, Balagué, Olga, Gel, Bernat, Abrisqueta, Pau, Lopez-Guillermo, Armando, Artells, Rosa, Montserrat, Emili, Monzo, Mariano

“…MicroRNAs (miRNAs) are negative regulators of gene expression that play an important role in hematopoiesis and tumorigenesis. We analyzed miRNA expression in…”
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Lestaurtinib inhibition of the Jak/STAT signaling pathway in hodgkin lymphoma inhibits proliferation and induces apoptosis by Diaz, Tania, Navarro, Alfons, Ferrer, Gerardo, Gel, Bernat, Gaya, Anna, Artells, Rosa, Bellosillo, Beatriz, Garcia-Garcia, Mar, Serrano, Sergi, Martínez, Antonio, Monzo, Mariano

“…Standard cytotoxic chemotherapy for Hodgkin Lymphoma (HL) has changed little in 30 years; the treatment for patients with relapsed or refractory disease…”
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The management of pregnancy in paroxysmal nocturnal haemoglobinuria on long term eculizumab by Kelly, Richard, Arnold, Louise, Richards, Stephen, Hill, Anita, Bomken, Charlotte, Hanley, John, Loughney, Andrew, Beauchamp, Jon, Khursigara, Gus, Rother, Russell P., Chalmers, Elizabeth, Fyfe, Andrew, Fitzsimons, Edward, Nakamura, Ryotaro, Gaya, Anna, Risitano, Antonio M., Schubert, Jörg, Norfolk, Derek, Simpson, Nigel, Hillmen, Peter

“…Summary In Paroxysmal nocturnal haemoglobinuria (PNH), pregnancy is associated with increased maternal and foetal complications to such an extent that the…”
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PB2064: THE COMPLETE STUDY: A SINGLE ARM, MULTICENTER OBSERVATIONAL STUDY TO EVALUATE EFFECTIVENESS OF PEGCETACOPLAN UNDER REAL WORLD CONDITIONS IN PATIENTS WITH PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) by Latour, Régis Peffault, Szer, Jeff, Kulasekararaj, Austin, Gaya, Anna, Sica, Simona, Nölte, Matthias, Horneff, Regina, Stefan, Lethagen

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Results of a phase 1/2 study of cemdisiran in healthy subjects and patients with paroxysmal nocturnal hemoglobinuria by Gaya, Anna, Munir, Talha, Urbano‐Ispizua, Alvaro, Griffin, Morag, Taubel, Jorg, Bush, Jim, Bhan, Ishir, Borodovsky, Anna, Wang, Yue, Badri, Prajakta, Garg, Pushkal

“…Complement dysregulation underpins the physiopathology of paroxysmal nocturnal hemoglobinuria (PNH). Cemdisiran, an RNA interference investigational treatment,…”
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MiR-SNPs as markers of toxicity and clinical outcome in Hodgkin lymphoma patients by Navarro, Alfons, Muñoz, Carmen, Gaya, Anna, Díaz-Beyá, Marina, Gel, Bernat, Tejero, Rut, Díaz, Tania, Martinez, Antonio, Monzó, Mariano

“…In recent years, microRNA (miRNA) pathways have emerged as a crucial system for the regulation of tumorogenesis. miR-SNPs are a novel class of single…”
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Hematopoiesis-related microRNA expression in myelodysplastic syndromes by Pons, Aina, Nomdedeu, Benet, Navarro, Alfons, Gaya, Anna, Gel, Bernat, Diaz, Tania, Valera, Sandra, Rozman, María, Belkaid, Mohamed, Montserrat, Emili, Monzo, Mariano

“…MicroRNAs (miRNAs) are negative regulators of expression of genes involved in hematopoiesis. The present study sought to link hematopoiesis-relevant miRNAs…”
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S181: THE PHASE III, RANDOMIZED COMMODORE 2 TRIAL: RESULTS FROM A MULTICENTER STUDY OF CROVALIMAB VS ECULIZUMAB IN PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) PATIENTS NAIVE TO COMPLEMENT INHIBITORS by Röth, Alexander, He, Guangsheng, Brodsky, Andres, Chai‐Adisaksopha, Chatree Chatree, Dumagay, Teresita, Demichelis, Roberta, Höglund, Martin, Kelly, Richard, Lee, Je‐Hwan, Nishimura, Jun‐Ichi, Obara, Naoshi, Risitano, Antonio Maria, Gaya, Anna, Appius, Anita, Gentile, Brittany, Negricea, Raluca, Zhang, Zilu, Buatois, Simon, Han, Bing

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S182: ORAL IPTACOPAN MONOTHERAPY INCREASES PAROXYSMAL NOCTURNAL HEMOGLOBINURIA (PNH) RED BLOOD CELL CLONE SIZE VIA CONTROL OF INTRA‐ AND EXTRAVASCULAR HEMOLYSIS IN ANTI‐C5‐TREATED PNH PATIENTS WITH ANEMIA by Risitano, Antonio Maria, Röth, Alexander, Kulasekararaj, Austin, Scheinberg, Phillip, Ueda, Yasutaka, Castro, Carlos, Bona, Eros DI, Griffin, Morag, Langemeijer, Saskia, Schrezenmeier, Hubert, Barcellini, Wilma, Mauad, Vitor Aq, Panse, Jens, Schafhausen, Philippe, Tavitian, Suzanne, Beggiato, Eloise, Gaya, Anna, Huang, Wei‐Han, Kitawaki, Toshio, Kutlar, Abdullah, Maciejewski, Jaroslaw P, Notaro, Rosario, Pullarkat, Vinod, Schubert, Jörg, Terriou, Louis, Uchiyama, Michihiro, Fontbrune, Flore Sicre, Marano, Luana, Alashkar, Ferras, Gandhi, Shreyans, Kerloëguen, Cécile, Kumar, Rakesh, Thorburn, Christine, Maitra, Samopriyo, Dahlke, Marion, Latour, Régis Peffault

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Piwirna-651 Expression Influences Treatment Response and Impacts Survival in Classical Hodgkin Lymphoma Patients through Regulation of ABCC5 by Navarro, Alfons, Cordeiro, Anna, Gaya, Anna, Gonzalez-Farre, Blanca, Díaz-Beyá, Marina, Fuster, Dolors, Martínez, Carmen, Esteve, Jordi, Martinez, Antonio, Monzó, Mariano

“…Introduction: PiwiRNAs (piRNAs) are small non-coding RNAs processed by PIWI proteins, a subfamily of Argonaute proteins. The main functions of piRNAs include…”
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Mannan-binding lectin pathway deficiencies and invasive fungal infections following allogeneic stem cell transplantation by Granell, Miquel, Urbano-Ispizua, Alvaro, Suarez, Belén, Rovira, Montserrat, Fernández-Avilés, Francesc, Martínez, Carmen, Ortega, Mar, Uriburu, Carla, Gaya, Anna, Roncero, Josep M a., Navarro, Alfons, Carreras, Enric, Mensa, Josep, Vives, Jordi, Rozman, Ciril, Montserrat, Emili, Lozano, Francisco

“…The Mannan-binding lectin (MBL) pathway involves recognition of fungal surfaces by MBL and cleavage of C2 and C4 by MBL-associated serine protease (namely,…”
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Case-Control Comparison of At-Home to Total Hospital Care for Autologous Stem-Cell Transplantation for Hematologic Malignancies by FERNANDEZ-AVILES, Francesc, CARRERAS, Enric, SEGURA, Susana, GARCIA, Lourdes, GONZALEZ, Manel, VALVERDE, Montserrat, MONTSERRAT, Emili, URBANO-ISPIZUA, Alvaro, ROVIRA, Montserrat, MARTINEZ, Carmen, GAYA, Anna, GRANELL, Miquel, RAMIRO, Laia, GALLEGO, Cristina, HERNANDO, Adela

“…One of the most significant limitations of at-home autologous stem-cell transplantation (ASCT) is the necessity for hospital readmission. We developed an…”
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Pegcetacoplan: climbing up the complement cascade by Gaya, Anna

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Role of kidney MRI to monitoring clearance of hemosiderin deposits in paroxysmal nocturnal hemoglobinuria by Piñeiro, Gaston Julio, Nicolau, Carlos, Gaya, Anna, Buñesch, Laura, Poch, Esteban

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Common variants in NLRP2 and NLRP3 genes are strong prognostic factors for the outcome of HLA-identical sibling allogeneic stem cell transplantation by Granell, Miquel, Urbano-Ispizua, Álvaro, Pons, Aina, Aróstegui, Juan Ignacio, Gel, Bernat, Navarro, Alfons, Jansa, Sonia, Artells, Rosa, Gaya, Anna, Talarn, Carme, Fernández-Avilés, Francesc, Martínez, Carmen, Rovira, Montserrat, Carreras, Enric, Rozman, Ciril, Juan, Manel, Yagüe, Jordi, Montserrat, Emili, Monzó, Mariano

“…The inflammasomes are macromolecular cytosolic complexes involved in the production of interleukin-1β (IL-1β) and IL-18 in response to several pathogen-derived…”
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