Search Results - "Gay, RE"

Expression and Regulation of Toll-Like Receptor 2 in Rheumatoid Arthritis Synovium by Seibl, Reinhart, Birchler, Thomas, Loeliger, Susanne, Hossle, Johann Peter, Gay, Renate E., Saurenmann, Traudl, Michel, Beat A., Seger, Reinhard A., Gay, Steffen, Lauener, Roger P.

“…Toll-like receptors (TLRs) are involved in mediating cell activation on stimulation with microbial constituents. We investigated the role for TLRs in synovial…”
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Immunohistologic Demonstration of Platelet-derived Growth Factor (PDGF) and sis-Oncogene Expression in Scleroderma by Gay, Steffen, Jones, Robert E., Huang, Guo-qiang, Gay, Renate E.

“…Although the pathogenesis and mechanisms responsible for excessive connective tissue deposition are not known, it has been thought that specific growth factors…”
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Downregulation of miR-193b in systemic sclerosis regulates the proliferative vasculopathy by urokinase-type plasminogen activator expression by Iwamoto, Naoki, Vettori, Serena, Maurer, Britta, Brock, Matthias, Pachera, Elena, Jüngel, Astrid, Calcagni, Maurizio, Gay, Renate E, Whitfield, Michael L, Distler, Jörg H W, Gay, Steffen, Distler, Oliver

“…To investigate the role of microRNA-193b-3p (miR-193b) in the vascular pathophysiology of systemic sclerosis (SSc). Expression of miR-193b in skin biopsies and…”
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The epigenetic architecture at gene promoters determines cell type-specific LPS tolerance by Klein, Kerstin, Frank-Bertoncelj, Mojca, Karouzakis, Emmanuel, Gay, Renate E., Kolling, Christoph, Ciurea, Adrian, Bostanci, Nagihan, Belibasakis, Georgios N., Lin, Lih-Ling, Distler, Oliver, Gay, Steffen, Ospelt, Caroline

“…Synovial fibroblasts (SF) drive inflammation and joint destruction in chronic arthritis. Here we show that SF possess a distinct type of LPS tolerance compared…”
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Mechanisms of Disease: the molecular and cellular basis of joint destruction in rheumatoid arthritis by Gay, Steffen, Müller-Ladner, Ulf, Pap, Thomas, Gay, Renate E, Neidhart, Michel

“…Rheumatoid arthritis is a complex systemic disease that ultimately leads to the progressive destruction of articular and periarticular structures. Novel data…”
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Anti-tumor necrosis factor-α treatment improves endothelial function in patients with rheumatoid arthritis by HÜRLIMANN, David, FORSTER, Adrian, GAY, Renate E, LÜSCHER, Thomas F, GAY, Steffen, RUSCHITZKA, Frank, NOLL, Georg, ENSELEIT, Frank, CHENEVARD, Rémy, DISTLER, Oliver, BECHIR, Markus, SPIEKER, Lukas E, NEIDHART, Michel, MICHEL, Beat A

“…Rheumatoid arthritis (RA) is associated with accelerated atherosclerosis and increased cardiovascular morbidity and mortality. Striking similarities exist in…”
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Uncontrolled Expression of Vascular Endothelial Growth Factor and Its Receptors Leads to Insufficient Skin Angiogenesis in Patients With Systemic Sclerosis by Distler, Oliver, Distler, Jörg H.W, Scheid, Annette, Acker, Till, Hirth, Astrid, Rethage, Janine, Michel, Beat A, Gay, Renate E, Müller-Ladner, Ulf, Matucci-Cerinic, Marco, Plate, Karl H, Gassmann, Max, Gay, Steffen

“…Systemic sclerosis (SSc) skin lesions are characterized by disturbed vessel morphology with enlarged capillaries and an overall reduction in capillary density,…”
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The Induction of Matrix Metalloproteinase and Cytokine Expression in Synovial Fibroblasts Stimulated with Immune Cell Microparticles by Jörg H. W. Distler, Jüngel, Astrid, Huber, Lars C., Seemayer, Christian A., Reich, Charles F., Gay, Renate E., Michel, Beat A., Fontana, Adriano, Gay, Steffen, Pisetsky, David S., Distler, Oliver, Dinarello, Charles A.

“…Rheumatoid arthritis is a chronic inflammatory disease characterized by destruction of cartilage and bone that is mediated by synovial fibroblasts. To…”
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Chemokine Secretion of Rheumatoid Arthritis Synovial Fibroblasts Stimulated by Toll-Like Receptor 2 Ligands by Pierer, Matthias, Rethage, Janine, Seibl, Reinhart, Lauener, Roger, Brentano, Fabia, Wagner, Ulf, Hantzschel, Holm, Michel, Beat A, Gay, Renate E, Gay, Steffen, Kyburz, Diego

“…To analyze the role of Toll-like receptors (TLR) in the pathogenesis of rheumatoid arthritis, we have assessed the effects of stimulation of cultured synovial…”
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Selective COX-2 inhibition improves endothelial function in coronary artery disease by CHENEVARD, Rémy, HÜRLIMANN, David, MICHEL, Beat, LÜSCHER, Thomas F, NOLL, Georg, RUSCHITZKA, Frank, BECHIR, Markus, ENSELEIT, Frank, SPIEKER, Lukas, HERMANN, Matthias, RIESEN, Walter, GAY, Steffen, GAY, Renate E, NEIDHART, Michel

“…There is an ongoing debate as to whether the gastrointestinal safety of COX-2 inhibition compared with nonsteroidal antiinflammatory drugs (NSAIDs) may come at…”
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Detection of interleukin 1β (IL-1β), IL-6, and tumor necrosis factor-α in skin of patients with fibromyalgia by SALEMI, Souzan, RETHAGE, Janine, WOLLINA, Uwe, MICHEL, Beat A, GAY, Renate E, GAY, Steffen, SPROTT, Haiko

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Comparative responsiveness of the disabilities of the arm, shoulder, and hand, the carpal tunnel questionnaire, and the SF-36 to clinical change after carpal tunnel release by Gay, Ralph E., Amadio, Peter C., Johnson, Jane C.

“…Purpose: The objective of this study was to compare the responsiveness (ability to accurately detect change) of 3 self-administered questionnaires to changes…”
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Angiogenic and angiostatic factors in systemic sclerosis: increased levels of vascular endothelial growth factor are a feature of the earliest disease stages and are associated with the absence of fingertip ulcers by Distler, Oliver, Del Rosso, Angela, Giacomelli, Roberto, Cipriani, Paola, Conforti, Maria L, Guiducci, Serena, Gay, Renate E, Michel, Beat A, Brühlmann, Pius, Müller-Ladner, Ulf, Gay, Steffen, Matucci-Cerinic, Marco

“…To examine whether the lack of sufficient neoangiogenesis in systemic sclerosis (SSc) is caused by a decrease in angiogenic factors and/or an increase in…”
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Synovial activation in rheumatoid arthritis by Ospelt, Caroline, Neidhart, Michel, Gay, Renate E, Gay, Steffen

“…Rheumatoid arthritis (RA) is a chronic inflammatory disease with progressive articular damage. Activated cells of the synovium produce pro-inflammatory and…”
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Simvastatin improves endothelial function in patients with rheumatoid arthritis by Hermann, Frank, Forster, Adrian, Chenevard, Rémy, Enseleit, Frank, Hürlimann, David, Corti, Roberto, Spieker, Lukas E., Frey, Diana, Hermann, Matthias, Riesen, Walter, Neidhart, Michel, Michel, Beat A., Hellermann, Jens P., Gay, Renate E., Lüscher, Thomas F., Gay, Steffen, Noll, Georg, Ruschitzka, Frank

“…[...]the aim of the present study was to evaluate the effects of statin therapy on vascular function, plasma lipids, and oxidative stress in patients with RA…”
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Synovial fibroblasts of patients with rheumatoid arthritis attach to and invade normal human cartilage when engrafted into SCID mice by Muller-Ladner, U, Kriegsmann, J, Franklin, BN, Matsumoto, S, Geiler, T, Gay, RE, Gay, S

“…Rheumatoid arthritis (RA) has been thought to be largely a T-cell-mediated disease. To evaluate the role of T-cell-independent pathways in RA, we examined the…”
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Differential effects of selective cyclooxygenase-2 inhibitors on endothelial function in salt-induced hypertension by HERMANN, Matthias, CAMICI, Giovanni, GAY, Steffen, LÜSCHER, Thomas F, RUSCHITZKA, Frank, FRATTON, Aisha, HURLIMANN, David, TANNER, Felix C, HELLERMANN, Jens P, FIEDLER, Martin, THIERY, Joachim, NEIDHART, Michel, GAY, Renate E

“…In view of the ongoing controversy about potential differences in cardiovascular safety of selective cyclooxygenase (COX)-2 inhibitors (coxibs), we compared…”
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Galectin-3 is induced in rheumatoid arthritis synovial fibroblasts after adhesion to cartilage oligomeric matrix protein by Neidhart, M, Zaucke, F, von Knoch, R, Jüngel, A, Michel, B A, Gay, R E, Gay, S

“…Background: Galectin-3 is expressed in the synovial tissue of patients with rheumatoid arthritis (RA), particularly at sites of joint destruction. Objective:…”
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Detection of synovial macrophages in an experimental rabbit model of antigen-induced arthritis: ultrasmall superparamagnetic iron oxide-enhanced MR imaging by Lutz, Amelie M, Seemayer, Christian, Corot, Claire, Gay, Renate E, Goepfert, Kerstin, Michel, Beat A, Marincek, Borut, Gay, Steffen, Weishaupt, Dominik

“…To evaluate intravenously administered ultrasmall superparamagnetic iron oxide (USPIO) as a marker of macrophage activity in an experimental rabbit model of…”
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Increased DNA fragmentation and ultrastructural changes in fibromyalgic muscle fibres by Sprott, H, Salemi, S, Gay, R E, Bradley, L A, Alarcón, G S, Oh, S J, Michel, B A, Gay, S

“…Objective: To determine whether there is evidence of increased DNA fragmentation and ultrastructural changes in muscle tissue of patients with fibromyalgia…”
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