Search Results - "Gay, Lauren"

Hybkit: a Python API and command-line toolkit for hybrid sequence data from chimeric RNA methods by Stribling, Daniel, Gay, Lauren A, Renne, Rolf

“…Experimental methods using microRNA/target ligation have recently provided significant insights into microRNA functioning through generation of chimeric…”
Get full text

Ago HITS-CLIP expands understanding of Kaposi's sarcoma-associated herpesvirus miRNA function in primary effusion lymphomas by Haecker, Irina, Gay, Lauren A, Yang, Yajie, Hu, Jianhong, Morse, Alison M, McIntyre, Lauren M, Renne, Rolf

“…KSHV is the etiological agent of Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and a subset of multicentricCastleman's disease (MCD). The fact that…”
Get full text

Computational analysis of ribonomics datasets identifies long non-coding RNA targets of γ-herpesviral miRNAs by Sethuraman, Sunantha, Thomas, Merin, Gay, Lauren A, Renne, Rolf

“…Abstract Ribonomics experiments involving crosslinking and immuno-precipitation (CLIP) of Ago proteins have expanded the understanding of the miRNA targetome…”
Get full text

Modified Cross-Linking, Ligation, and Sequencing of Hybrids (qCLASH) Identifies Kaposi's Sarcoma-Associated Herpesvirus MicroRNA Targets in Endothelial Cells by Gay, Lauren A, Sethuraman, Sunantha, Thomas, Merin, Turner, Peter C, Renne, Rolf

“…Kaposi's sarcoma (KS) tumors are derived from endothelial cells and express Kaposi's sarcoma-associated herpesvirus (KSHV) microRNAs (miRNAs). Although miRNA…”
Get full text

Kaposi's Sarcoma-associated Herpesvirus microRNA mutants modulate cancer hallmark phenotypic differences in human endothelial cells by Gay, Lauren A, Stribling, Daniel, Turner, Peter C, Renne, Rolf

“…Kaposi's sarcoma (KS) results from the transformation of Kaposi's sarcoma-associated herpesvirus (KSHV)-infected endothelial cells. The contribution of the…”
Get full text

Identification of murine gammaherpesvirus 68 miRNA-mRNA hybrids reveals miRNA target conservation among gammaherpesviruses including host translation and protein modification machinery by Bullard, Whitney L, Kara, Mehmet, Gay, Lauren A, Sethuraman, Sunantha, Wang, Yiping, Nirmalan, Shreya, Esemenli, Alim, Feswick, April, Hoffman, Brett A, Renne, Rolf, Tibbetts, Scott A

“…Gammaherpesviruses, including the human pathogens Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV), establish lifelong latent…”
Get full text

Cross-Linking Ligation and Sequencing of Hybrids (qCLASH) Reveals an Unpredicted miRNA Targetome in Melanoma Cells by Kozar, Ines, Philippidou, Demetra, Margue, Christiane, Gay, Lauren A, Renne, Rolf, Kreis, Stephanie

“…MicroRNAs are key post-transcriptional gene regulators often displaying aberrant expression patterns in cancer. As microRNAs are promising disease-associated…”
Get full text

DExD/H Box Helicases DDX24 and DDX49 Inhibit Reactivation of Kaposi's Sarcoma Associated Herpesvirus by Interacting with Viral mRNAs by Serfecz, Jacquelyn C, Hong, Yuan, Gay, Lauren A, Shekhar, Ritu, Turner, Peter C, Renne, Rolf

“…Kaposi's sarcoma-associated herpesvirus (KSHV) is an oncogenic gammaherpesvirus that is the causative agent of primary effusion lymphoma and Kaposi's sarcoma…”
Get full text

Age-Related Changes in miRNA Expression Influence GSTZ1 and Other Drug Metabolizing Enzymes by Jahn, Stephan, Gay, Lauren, Weaver, Claire, Renne, Rolf, Langaee, Taimour Y, Stacpoole, Peter W, James, Margaret O

“…Previous work has shown that hepatic levels of human glutathione transferase zeta 1 (GSTZ1) protein, involved in tyrosine catabolism and responsible for…”
Get full text

KSHV miRNAs decrease expression of lytic genes in latently infected PEL and endothelial cells by targeting host transcription factors by Plaisance-Bonstaff, Karlie, Choi, Hong Seok, Beals, Tyler, Krueger, Brian J, Boss, Isaac W, Gay, Lauren A, Haecker, Irina, Hu, Jianhong, Renne, Rolf

“…Kaposi's sarcoma-associated herpesvirus (KSHV) microRNAs are encoded in the latency-associated region. Knockdown of KSHV miR-K12-3 and miR-K12-11 increased…”
Get full text

Sequencing of Argonaute-bound microRNA/mRNA hybrids reveals regulation of the unfolded protein response by microRNA-320a by Fields, Christopher J, Li, Lu, Hiers, Nicholas M, Li, Tianqi, Sheng, Peike, Huda, Taha, Shan, Jixiu, Gay, Lauren, Gu, Tongjun, Bian, Jiang, Kilberg, Michael S, Renne, Rolf, Xie, Mingyi

“…MicroRNAs (miRNA) are short non-coding RNAs widely implicated in gene regulation. Most metazoan miRNAs utilize the RNase III enzymes Drosha and Dicer for…”
Get full text

PDGFRA defines the mesenchymal stem cell Kaposi's sarcoma progenitors by enabling KSHV oncogenesis in an angiogenic environment by Naipauer, Julian, Rosario, Santas, Gupta, Sachin, Premer, Courtney, Méndez-Solís, Omayra, Schlesinger, Mariana, Ponzinibbio, Virginia, Jain, Vaibhav, Gay, Lauren, Renne, Rolf, Chan, Ho Lam, Morey, Lluis, Salyakina, Daria, Abba, Martin, Williams, Sion, Hare, Joshua M, Goldschmidt-Clermont, Pascal J, Mesri, Enrique A

“…Kaposi's sarcoma (KS) is an AIDS-defining cancer caused by the KS-associated herpesvirus (KSHV). Unanswered questions regarding KS are its cellular ontology…”
Get full text

Contemporary Ribonomics Methods for Viral microRNA Target Analysis by Gay, Lauren A, Turner, Peter C, Renne, Rolf

“…Numerous cellular processes are regulated by microRNAs (miRNAs), both cellular and viral. Elucidating the targets of miRNAs has become an active area of…”
Get full text

Attachment Style and Early Maladaptive Schemas as Mediators of the Relationship between Childhood Emotional Abuse and Intimate Partner Violence by Gay, Lauren E., Harding, Hilary G., Jackson, Joan L., Burns, Erin E., Baker, Brittany D.

“…Theoretical and empirical research suggests possible pathways between women's experiences of childhood emotional abuse (CEA) and later intimate partner…”
Get full text

microRNA dependent and independent deregulation of long non-coding RNAs by an oncogenic herpesvirus by Sethuraman, Sunantha, Gay, Lauren Appleby, Jain, Vaibhav, Haecker, Irina, Renne, Rolf

“…Kaposi's sarcoma (KS) is a highly prevalent cancer in AIDS patients, especially in sub-Saharan Africa. Kaposi's sarcoma-associated herpesvirus (KSHV) is the…”
Get full text

Human Cytomegalovirus Latency and Myelosuppression: A microRNA-Dependent Yin and Yang Regulatory Loop by Gay, Lauren, Renne, Rolf

“…In this issue of Cell Host & Microbe, Hancock et al., 2020 show that latent HCMV infection, and specifically miR-US5-2, induces TGF-β secretion, which inhibits…”
Get full text

Construction and utilization of a new generation of bacteriophage-based particles, or TPA, for guided systemic delivery of nucleic acids to tumors by Gay, Lauren, Suwan, Keittisak, Hajitou, Amin

“…Successful delivery of nucleic acid therapeutics to diseased sites would present a pivotal advancement in cancer treatment. However, progress has been hindered…”
Get full text

Abstract 1690 Repression of cancer-immunity regulator STING by Kaposi's Sarcoma-Associated Herpesvirus (KSHV) microRNA by Paulsen, Kimberly, Chan, Rosenna, Gay, Lauren, Renne, Rolf, Ma, Zhe

Get full text

Correction: Ago HITS-CLIP Expands Understanding of Kaposi's Sarcoma-associated Herpesvirus miRNA Function in Primary Effusion Lymphomas by Haecker, Irina, Gay, Lauren A., Yang, Yajie, Hu, Jianhong, Morse, Alison M., McIntyre, Lauren M., Renne, Rolf

Get full text

Political Polarization, Ingroup Bias, and Helping Behavior: Do We Help Others Who Are “on the Other Political Team?” by Fitapelli, Brianna, Hewett, Samantha, McQuade, Briana, Berg, Emma, Thaler, Dalia, Gay, Lauren, Rodriguez, Tiana, Thomas, Dayna M., Akhmadi, Ferdaus, Geher, Glenn

“…The American social and political climate has become increasingly polarized. To explore the effects of politically based ingroup biases as they relate to…”
Get full text