Search Results - "Gawrisch, K"

Liquid Domains in Vesicles Investigated by NMR and Fluorescence Microscopy by Veatch, S.L., Polozov, I.V., Gawrisch, K., Keller, S.L.

“…We use 2H-NMR, 1H-MAS NMR, and fluorescence microscopy to detect immiscibility in three particular phospholipid ratios mixed with 30% cholesterol: 2:1…”
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Membrane lateral compressibility determined by NMR and x-ray diffraction: effect of acyl chain polyunsaturation by Koenig, B.W., Strey, H.H., Gawrisch, K.

“…The elastic area compressibility modulus, Ka, of lamellar liquid crystalline bilayers was determined by a new experimental approach using 2H-NMR order…”
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Neutron Reflectivity and Atomic Force Microscopy Studies of a Lipid Bilayer in Water Adsorbed to the Surface of a Silicon Single Crystal by Koenig, B. W, Krueger, S, Orts, W. J, Majkrzak, C. F, Berk, N. F, Silverton, J. V, Gawrisch, K

“…Specular reflection of neutrons has been used to characterize the structure of single lipid bilayers adsorbed to a planar silicon surface from aqueous…”
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Dehydration Induces Lateral Expansion of Polyunsaturated 18:0–22:6 Phosphatidylcholine in a New Lamellar Phase by Binder, H., Gawrisch, K.

“…To gain a better understanding of the biological role of polyunsaturated phospholipids, infrared (IR) linear dichroism, NMR, and x-ray diffraction studies have…”
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Effect of unsaturation on the chain order of phosphatidylcholines in a dioleoylphosphatidylethanolamine matrix by Separovic, F., Gawrisch, K.

“…The properties of phosphatidylcholines (PCs) having a perdeuterated stearic acid, 18:0d35, in the sn-1 position and the fatty acid 18:0, 18:1 omega 9, 18:2…”
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Direct Measurement of Salt-Bridge Solvation Energies Using a Peptide Model System: Implications for Protein Stability by Wimley, William C., Gawrisch, Klaus, Creamer, Trevor P., White, Stephen H.

“…The solvation energies of salt bridges formed between the terminal carboxyl of the host pentapeptide AcWL-X-LL and the side chains of Arg or Lys in the guest…”
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2H nuclear magnetic resonance order parameter profiles suggest a change of molecular shape for phosphatidylcholines containing a polyunsaturated acyl chain by Holte, L.L., Peter, S.A., Sinnwell, T.M., Gawrisch, K.

“…Solid-state 2H nuclear magnetic resonance spectroscopy was used to determine the orientational order parameter profiles for a series of phosphatidylcholines…”
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Membrane dipole potentials, hydration forces, and the ordering of water at membrane surfaces by Gawrisch, K., Ruston, D., Zimmerberg, J., Parsegian, V.A., Rand, R.P., Fuller, N.

“…We have compared hydration forces, electrical dipole potentials, and structural parameters of dispersions of dipalmitoylphosphatidylcholine (DPPC) and…”
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Bond Orientational Order, Molecular Motion, and Free Energy of High-Density DNA Mesophases by Podgornik, R., Strey, H. H., Gawrisch, K., Rau, D. C., Rupprecht, A., Parsegian, V. A.

“…By equilibrating condensed DNA arrays against reservoirs of known osmotic stress and examining them with several structural probes, it has been possible to…”
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Why is docosahexaenoic acid essential for nervous system function? by Mitchell, D C, Gawrisch, K, Litman, B J, Salem, Jr, N

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Small concentrations of alamethicin induce a cubic phase in bulk phosphatidylethanolamine mixtures by Keller, S.L, Gruner, S.M, Gawrisch, K

“…Under normal conditions, excess water dispersions of liquid crystalline 1,2-dielaidoyl- sn-glycero-3-phosphoethanolamine (DEPE) are known to convert from a…”
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Nuclear magnetic resonance investigation of hydrocarbon chain packing in bilayers of polyunsaturated phospholipids by Holte, L. L., Separovic, F., Gawrisch, K.

“…2H nuclear magnetic resonance (NMR) on chaindeuterated phospholipids has been used to study the influence of the degree of unsaturation on lipid chain packing…”
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Increased adhesion between neutral lipid bilayers: interbilayer bridges formed by tannic acid by Simon, S.A., Disalvo, E.A., Gawrisch, K., Borovyagin, V., Toone, E., Schiffman, S.S., Needham, D., McIntosh, T.J.

“…Tannic acid (TA) is a naturally occurring polyphenolic compound that aggregates membranes and neutral phosolipid vesicles and precipitates many proteins. This…”
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Energetics of a hexagonal-lamellar-hexagonal-phase transition sequence in dioleoylphosphatidylethanolamine membranes by Gawrisch, Klaus, Parsegian, V. Adrian, Hajduk, Damian A, Tate, Mark W, Gruner, Sol M, Fuller, Nola L, Rand, R. Peter

“…The phase diagram of DOPE/water dispersions was investigated by NMR and X-ray diffraction in the water concentration range from 2 to 20 water molecules per…”
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Water permeability of polyunsaturated lipid membranes measured by 17O NMR by Huster, D., Jin, A.J., Arnold, K., Gawrisch, K.

“…Diffusion-controlled water permeation across bilayers of polyunsaturated phospholipids was measured by 17O nuclear magnetic resonance. In 100-nm extruded…”
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Polyunsaturated Fatty Acids in Lipid Bilayers:  Intrinsic and Environmental Contributions to Their Unique Physical Properties by Feller, Scott E, Gawrisch, Klaus, MacKerell, Alexander D

“…Polyunsaturated lipids are an essential component of biological membranes, influencing order and dynamics of lipids, protein−lipid interaction, and membrane…”
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Properties of docosahexaenoic-acid-containing lipids and their influence on the function of rhodopsin by Feller, Scott E, Gawrisch, Klaus

“…The importance of highly polyunsaturated fatty acids in health and development has been convincingly demonstrated by many studies over the past several…”
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Mechanisms of action of docosahexaenoic acid in the nervous system by Salem, Norman, Litman, Burton, Kim, Hee‐Yong, Gawrisch, Klaus

“…Abtract This review describes (from both the animal and human literature) the biological consequences of losses in nervous system docosahexaenoate (DHA). It…”
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Internal Hydration Increases during Activation of the G-Protein-Coupled Receptor Rhodopsin by Grossfield, Alan, Pitman, Michael C., Feller, Scott E., Soubias, Olivier, Gawrisch, Klaus

“…Rhodopsin, the membrane protein responsible for dim-light vision, until recently was the only G-protein-coupled receptor (GPCR) with a known crystal structure…”
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Lipid−Rhodopsin Hydrophobic Mismatch Alters Rhodopsin Helical Content by Soubias, Olivier, Niu, Shui-Lin, Mitchell, Drake C, Gawrisch, Klaus

“…The ability of photoactivated rhodopsin to achieve the enzymatically active metarhodopsin II conformation is exquisitely sensitive to bilayer hydrophobic…”
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