Search Results - "Gawor, Klara"

TDP-43 pathology is associated with increased tau burdens and seeding by Tomé, Sandra O, Tsaka, Grigoria, Ronisz, Alicja, Ospitalieri, Simona, Gawor, Klara, Gomes, Luis Aragão, Otto, Markus, von Arnim, Christine A. F, Van Damme, Philip, Van Den Bosch, Ludo, Ghebremedhin, Estifanos, Laureyssen, Celeste, Sleegers, Kristel, Vandenberghe, Rik, Rousseau, Frederic, Schymkowitz, Joost, Thal, Dietmar Rudolf

“…Background Most Alzheimer's Disease (AD) cases also exhibit limbic predominant age-related TDP-43 encephalopathy neuropathological changes (LATE-NC), besides…”
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LATE-NC aggravates GVD-mediated necroptosis in Alzheimer's disease by Koper, Marta J, Tomé, Sandra O, Gawor, Klara, Belet, Annelies, Van Schoor, Evelien, Schaeverbeke, Jolien, Vandenberghe, Rik, Vandenbulcke, Mathieu, Ghebremedhin, Estifanos, Otto, Markus, von Arnim, Christine A F, Balusu, Sriram, Blaschko, Matthew B, De Strooper, Bart, Thal, Dietmar Rudolf

“…It has become evident that Alzheimer's Disease (AD) is not only linked to its hallmark lesions-amyloid plaques and neurofibrillary tangles (NFTs)-but also to…”
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Regulated cell death and its role in Alzheimer’s disease and amyotrophic lateral sclerosis by Thal, Dietmar Rudolf, Gawor, Klara, Moonen, Sebastiaan

“…Despite considerable research efforts, it is still not clear which mechanisms underlie neuronal cell death in neurodegenerative diseases. During the last…”
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LATE‐NC in Alzheimer's disease: Molecular aspects and synergies by Tomé, Sandra O., Gawor, Klara, Thal, Dietmar Rudolf

“…Alzheimer's disease (AD) is classically characterized by senile plaques and neurofibrillary tangles (NFTs). However, multiple copathologies can be observed in…”
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Association of hippocampal neuron loss, pTDP‐43, and Alzheimer’s disease pathology with the presence of cerebral Lewy bodies by Gawor, Klara, Tomé, Sandra O., Ronisz, Alicja, Ospitalieri, Simona, Vandenberghe, Rik, von Arnim, Christina, Otto, Markus, Thal, Dietmar Rudolf

“…Background The presence of multiple brain pathologies in patients with late‐onset dementia was shown to be a rule rather than an exception. Studies have shown…”
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The impact of co‐morbid LATE‐NC pathology in Alzheimer’s Disease by Tomé, Sandra O., Tsaka, Grigoria, Ronisz, Alicja, Ospitalieri, Simona, Gawor, Klara, von Arnim, Christina, Otto, Markus, Vandenberghe, Rik, Schymkowitz, Joost, Rousseau, Frederic, Thal, Dietmar Rudolf

“…Background TDP‐43 is known to co‐accumulate in the brains of most Alzheimer’s Disease (AD) cases, in addition to amyloid‐β plaques and tau tangles, and it has…”
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Hypothesis-based investigation of known AD risk variants reveals the genetic underpinnings of neuropathological lesions observed in Alzheimer’s-type dementia by Laureyssen, Celeste, Küçükali, Fahri, Van Dongen, Jasper, Gawor, Klara, Tomé, Sandra O., Ronisz, Alicja, Otto, Markus, von Arnim, Christine A. F., Van Damme, Philip, Vandenberghe, Rik, Thal, Dietmar Rudolf, Sleegers, Kristel

“…Alzheimer’s disease (AD) is the leading cause of dementia worldwide. Besides neurofibrillary tangles and amyloid beta (A β ) plaques, a wide range of co-morbid…”
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Single nucleotide polymorphisms linked to Alzheimer’s disease are associated with distinct neuropathological phenotypes by Laureyssen, Celeste, Gawor, Klara, Van Dongen, Jasper, Kucukali, Fahri, Koper, Marta J, Ronisz, Alicja, Otto, Markus, von Arnim, Christine, Van Damme, Philip, Vandenberghe, Rik, Thal, Dietmar Rudolf, Sleegers, Kristel

“…Background Neurodegenerative brain diseases (NBDs) ultimately result in neuronal loss and subsequent cognitive decline. In Alzheimer’s disease, tau…”
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Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology (vol 53, pg 1636, 2021) by van, Rheenen W, van, der Spek RAA, Bakker, MK, van, Vugt JJFA, Hop, PJ, Zwamborn, RAJ, de, Klein N, Westra, H-J, Bakker, OB, Deelen, P

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Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology by van Rheenen, Wouter, van der Spek, Rick a A, Bakker, Mark K, van Vugt, Joke J F A, Hop, Paul J, Zwamborn, Ramona a J, de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B, Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M, Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H P, van Eijk, Kristel R, Kooyman, Maarten, Byrne, Ross P, Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola, Cooper-Knock, Johnathan, Smith, Bradley N, Gromicho, Marta, Chandran, Siddharthan, Pal, Suvankar, Morrison, Karen E, Shaw, Pamela J, Hardy, John, Orrell, Richard W, Sendtner, Michael, Meyer, Thomas, Başak, Nazli, van der Kooi, Anneke J, Ratti, Antonia, Fogh, Isabella, Gellera, Cinzia, Lauria, Giuseppe, Corti, Stefania, Cereda, Cristina, Sproviero, Daisy, d'Alfonso, Sandra, Sorarù, Gianni, Siciliano, Gabriele, Filosto, Massimiliano, Padovani, Alessandro, Chiò, Adriano, Calvo, Andrea, Moglia, Cristina, Brunetti, Maura, Canosa, Antonio, Grassano, Maurizio, Beghi, Ettore, Pupillo, Elisabetta, Logroscino, Giancarlo, Nefussy, Beatrice, Osmanovic, Alma, Nordin, Angelica, Lerner, Yossef, Zabari, Michal, Gotkine, Marc, Baloh, Robert H, Bell, Shaughn, Vourc'H, Patrick, Corcia, Philippe, Couratier, Philippe, Millecamps, Stéphanie, Meininger, Vincent, Salachas, François, Mora Pardina, Jesus S, Assialioui, Abdelilah, Rojas-García, Ricardo, Dion, Patrick A, Ross, Jay P, Ludolph, Albert C, Weishaupt, Jochen H, Brenner, David, Freischmidt, Axel, Bensimon, Gilbert, Brice, Alexis, Durr, Alexandra, Payan, Christine a M, Saker-Delye, Safa, Wood, Nicholas W, Topp, Simon, Rademakers, Rosa, Tittmann, Lukas, Lieb, Wolfgang, Franke, Andre, Ripke, Stephan, Braun, Alice, Kraft, Julia

“…Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a lifetime risk of one in 350 people and an unmet need for disease-modifying…”
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