Search Results - "Gawell, L"

New Diarylmethylpiperazines as Potent and Selective Nonpeptidic δ Opioid Receptor Agonists with Increased In Vitro Metabolic Stability by Plobeck, Niklas, Delorme, Daniel, Wei, Zhong-Yong, Yang, Hua, Zhou, Fei, Schwarz, Peter, Gawell, Lars, Gagnon, Hélène, Pelcman, Benjamin, Schmidt, Ralf, Yue, Shi Yi, Walpole, Christopher, Brown, William, Zhou, Edward, Labarre, Maryse, Payza, Kemal, St-Onge, Stephane, Kamassah, Augustus, Morin, Pierre-Emmanuel, Projean, Denis, Ducharme, Julie, Roberts, Edward

“…Nonpeptide δ opioid agonists are analgesics with a potentially improved side-effect and abuse liability profile, compared to classical opioids. Andrews…”
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N,N-Diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide:  A Novel, Exceptionally Selective, Potent δ Opioid Receptor Agonist with Oral Bioavailability and Its Analogues by Wei, Zhong-Yong, Brown, William, Takasaki, Bryan, Plobeck, Niklas, Delorme, Daniel, Zhou, Fei, Yang, Hua, Jones, Paul, Gawell, Lars, Gagnon, Helene, Schmidt, Ralf, Yue, Shi-Yi, Walpole, Chris, Payza, Kemal, St-Onge, Stephane, Labarre, Maryse, Godbout, Claude, Jakob, Andrea, Butterworth, Joanne, Kamassah, Augustus, Morin, Pierre-Emmanuel, Projean, Denis, Ducharme, Julie, Roberts, Edward

“…The design, synthesis, and pharmacological evaluation of a novel class of δ opioid receptor agonists, N,N-diethyl-4-(phenylpiperidin-4-ylidenemethyl)benzamide…”
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Binding of a specific 5-HT uptake inhibitor, [3H]norzimelidine, to rat brain homogenates by Hall, H, Ross, S, Ogren, S O, Gawell, L

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Synthesis of N, N-diethyl-4-[phenyl-(piperidin-4-ylidene)methyl]-[carboxy-14C]benzamide, a potent δ opioid receptor agonist by Gawell, Lars

“…The synthesis of carbon‐14 labelled N,N‐diethyl‐4‐[phenyl‐(piperidin‐4‐ylidene)methyl]‐benzamide is described. The radioisotope is introduced via an…”
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Preventing Biomolecular Adsorption in Electrowetting-Based Biofluidic Chips by Yoon, Jeong-Yeol, Garrell, Robin L

“…Electrowetting-on-dielectric (EWOD) is a new method for moving liquids in biofluidic chips through electrical modification of the surface hydrophobicity…”
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Synthesis of 5-substituted 5-hydroxy-2-pyrrolidones, metabolites of the antipsychotic benzamide remoxipride by Gawell, L, Hagberg, C E, Högberg, T, Widman, M

“…This paper describes the synthesis of 5-[(3-bromo-2,6-dimethoxybenzamido)-methyl]-5-hydroxy-2-pyrrolidon e (3) and its 1-ethyl analogue 2, two urinary…”
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Studies on orchidaceae alkaloids. XXII. Synthesis and absolute configuration of pierardine. Lactone-betaine isomerization of shihunine by Elander, M, Gawell, L, Leander, K

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Studies on orchidaceae alkaloids. XXXVII. Dendrowardine, a quaternary alkaloid from Dendrobium wardianum Wr by Glomqvist, L, Brandänge, S, Gawell, L, Leander, K, Lüning, B

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Functional genomics of the GPCR family: Identification of novel drug targets for CNS diseases and pain control by Walker, P., Lembo, P., O'Donnell, D., Groblewski, T., Hoffert, C., Grazzini, E., Pelletier, M., Schmidt, R., Duchesne, M., Payza, K., Gawell, L., Ahmad, S.

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Some in vitro receptor binding properties of [3H]eticlopride, a novel substituted benzamide, selective for dopamine-D2 receptors in the rat brain by Hall, H, Köhler, C, Gawell, L

“…The substituted benzamide compound eticlopride, (S)-(-)-5-chloro-3-ethyl-N-[(1-ethyl-2-pyrrolidinyl) methyl]-6-methoxysalicylamide hydrochloride (FLB 131), has…”
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Regional in vivo binding of the substituted benzamide [3H]eticlopride in the rat brain: evidence for selective labelling of dopamine receptors by Köhler, C, Hall, H, Gawell, L

“…The novel substituted benzamide eticlopride, (S)-(-)-5-chloro-3-ethyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-6-methoxy salicylamide hydrochloride (A38503; FLB…”
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Raclopride, a new selective ligand for the dopamine-D2 receptors by Hall, H, Köhler, C, Gawell, L, Farde, L, Sedvall, G

“…1. The use of raclopride, a new compound of the salicylamide series, as a ligand for the labelling of dopamine-D2 receptors in vitro and in vivo is described…”
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Specific in vitro and in vivo binding of 3H-raclopride. A potent substituted benzamide drug with high affinity for dopamine D-2 receptors in the rat brain by Köhler, C, Hall, H, Ogren, S O, Gawell, L

“…The substituted benzamide drug raclopride, [((-)-(S)-3,5-dichloro-N-((1-ethyl-2-pyrrolidinyl) methyl)-6-methoxy-salicylamide tartrate; FLA 870(-); A40664] was…”
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Studies on orchidaceae alkaloids. 33. Two new alkaloids, N-cis- and N-trans-cinnamoyl-norcuskhygrine from Dendrobium chrysanthum Wall by Ekevåg, U, Elander, M, Gawell, L, Leander, K, Lüning, B

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Stereoselective high-affinity binding of 3H-alaproclate to membranes from rat cerebral cortex by Ross, S B, Gawell, L, Hall, H

“…The binding of 3H-alaproclate, a selective 5-hydroxytryptamine uptake inhibitor, to membranes prepared from the rat cerebral cortex was investigated by a…”
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