Search Results - "Gaw, A."

‘The principles of a future pharmacology’: Johann Christian Reil (1759–1813) and his role in the development of clinical pharmacology by Gaw, A.

“…Aim Johann Christian Reil was an eighteenth-century German physician and clinical academic with wide interests. These included building the scientific…”
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Management of patients at risk of adrenal crisis in the dental setting: a review of current practice in UK dental teaching hospitals by Gaw, A Gemma, Wemyss, Callum, Bell, Aileen, Goodall, Christine A

“…Introduction Patients with impaired corticosteroid response due to Addison's disease or systemic glucocorticoid use are at risk of adrenal crisis when…”
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Dynamic Regulation of the Endocannabinoid System: Implications for Analgesia by Sagar, Devi Rani, Gaw, A Gemma, Okine, Bright N, Woodhams, Stephen G, Wong, Amy, Kendall, David A, Chapman, Victoria

“…The analgesic effects of cannabinoids are well documented, but these are often limited by psychoactive side-effects. Recent studies indicate that the…”
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En Bloc Transplantation of Horseshoe Kidney from Deceased Donor: An Unusual Transplantation Utilizing Kidneys with Congenital Fusion Abnormality by Sengupta, Bodhisatwa, Khan, Iftikhar, Saiaghi, Akram, Gaw, Ethar A., Tawfeeq, Mansour, AlQahtani, Mohammed S., Obeid, Mahmoud

“…Transplanting horseshoe kidneys is challenging and has higher complication rates due to the unusual anatomy of the vascular and urinary collecting systems…”
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The care gap: underuse of statin therapy in the elderly by Gaw, A

“…Atherosclerotic diseases are responsible for the majority of deaths in the elderly, and they can also increase the risk of disability. Statins are first-line…”
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Genetic variation in the interleukin-1β-converting enzyme associates with cognitive function. The PROSPER study by Trompet, S., de Craen, A. J. M., Slagboom, P., Shepherd, J., Blauw, G. J., Murphy, M. B., Bollen, E. L. E. M., Buckley, B. M., Ford, I., Gaw, A., Macfarlane, P. W., Packard, C. J., Stott, D. J., Jukema, J. W., Westendorp, R. G. J.

“…Inflammation is thought to play an important role in the development of cognitive decline and dementia in old age. The interleukin-1 signalling pathway may…”
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Healthy ageing: addressing acute coronary syndrome? by GAW, A

“…Acute coronary syndromes contribute significantly to the patterns of morbidity and mortality in the elderly. A meta-analysis of the pathology of acute…”
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Genetic variation in the interleukin-10 gene promoter and risk of coronary and cerebrovascular events: the PROSPER study by Trompet, S, Pons, D, DE Craen, A J M, Slagboom, P, Shepherd, J, Blauw, G J, Murphy, M B, Cobbe, S M, Bollen, E L E M, Buckley, B M, Ford, I, Hyland, M, Gaw, A, Macfarlane, P W, Packard, C J, Norrie, J, Perry, I J, Stott, D J, Sweeney, B J, Twomey, C, Westendorp, R G J, Jukema, J W

“…Proinflammatory cytokines, like interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-alpha), are implicated in the development of atherosclerosis. The…”
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Testing cognitive function in elderly populations: the PROSPER study by Houx, P J, Shepherd, J, Blauw, G-J, Murphy, M B, Ford, I, Bollen, E L, Buckley, B, Stott, D J, Jukema, W, Hyland, M, Gaw, A, Norrie, J, Kamper, A M, Perry, I J, MacFarlane, P W, Meinders, A Edo, Sweeney, B J, Packard, C J, Twomey, C, Cobbe, S M, Westendorp, R G

“…Objectives: For large scale follow up studies with non-demented patients in which cognition is an endpoint, there is a need for short, inexpensive, sensitive,…”
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Beyond consent: the potential for atrocity by Gaw, A.

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Vacuum Ultraviolet Spectroscopy and Mass Spectrometry: A Tandem Detection Approach for Improved Identification of Gas Chromatography-Eluting Compounds by Anthony, Ian G. M, Brantley, Matthew R, Gaw, Christina A, Floyd, Adam R, Solouki, Touradj

“…For wide class characterizations of volatile organic compounds (VOCs), conventional gas chromatography mass spectrometry (GC-MS)-based techniques are utilized…”
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Effect of individualizing starting doses of a statin according to baseline LDL-cholesterol levels on achieving cholesterol targets: The Achieve Cholesterol Targets Fast with Atorvastatin Stratified Titration (ACTFAST) study by Martineau, P, Gaw, A, de Teresa, E, Farsang, C, Gensini, G.F, Leiter, L.A, Langer, A

“…Abstract Aims To investigate whether selecting the starting dose of atorvastatin according to baseline and target (<2.6 mmol/L) LDL-cholesterol (LDL-C) values…”
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Primary prevention: a simple, effective means of risk reduction by Gaw, A

“…Individuals without overt coronary heart disease (CHD) may nevertheless be at significant risk for future CHD events based on lipid and other risk factors…”
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A multicentre, open study to assess the effect of individualizing starting doses of atorvastatin according to baseline LDL-C levels on achieving cholesterol targets: the Achieve Cholesterol Targets Fast with Atorvastatin Stratified Titration (ACTFAST-2) study by Farsang, C., Athyros, V., Gaw, A.

“…ABSTRACT Objectives: ACTFAST-2 was designed to match the starting dose of a statin to the baseline low density lipoprotein-cholesterol (LDL-C) value, to allow…”
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Effect of atorvastatin on circulating hsCRP concentrations: A sub-study of the Achieve Cholesterol Targets Fast with Atorvastatin Stratified Titration (ACTFAST) study by Gensini, G.F, Gori, A.M, Dilaghi, B, Rostagno, C, Gaw, A, Blanco-Colio, L.M, de Teresa, E, Egido, J, Farsang, C, Leiter, L.A, Martineau, P, Nozza, A, Langer, A

“…Abstract Background Elevated C-reactive protein (CRP) concentration is a risk factor for cardiovascular events that may add prognostic information. Statin…”
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Improving Accuracy and Confidence of Chemical Identification by Gas Chromatography/Vacuum Ultraviolet Spectroscopy-Mass Spectrometry: Parallel Gas Chromatography, Vacuum Ultraviolet, and Mass Spectrometry Library Searches by Anthony, Ian G. M, Brantley, Matthew R, Floyd, Adam R, Gaw, Christina A, Solouki, Touradj

“…Chemical identification often relies on matching measured chemical properties and/or spectral “fingerprints” of unknowns against their precompiled libraries…”
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Parathyroid hormone potentiates nucleotide-induced [Ca2+](i) release in rat osteoblasts independently of G(q) activation or cyclic monophosphate accumulation - A mechanism for localizing systemic responses in bone by Buckley, K. A., Wagstaff, S. C., Mckay, G., Gaw, A., Hipskind, R. A., Bilbe, G., Gallagher, J. A., Bowler, W. B.

“…The regulation of tissue turnover requires the coordinated activity of both local and systemic factors. Nucleotides exist transiently in the extracellular…”
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Suicide among immigrants from the Indian subcontinent: a review by Patel, S P, Gaw, A C

“…Studies of suicide among immigrants from the Indian subcontinent (India, Pakistan, Bangladesh, and Sri Lanka) were examined to increase awareness of suicide…”
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Lymphotoxin-alpha C804A polymorphism is a risk factor for stroke. The PROSPER study by Trompet, S., de Craen, A.J.M., Slagboom, P., Shepherd, J., Blauw, G.J., Murphy, M.B., Bollen, E.L.E.M., Buckley, B.M., Ford, I., Gaw, A., Macfarlane, P.W., Packard, C.J., Stott, D.J., Westendorp, R.G.J., Jukema, J.W.

“…Inflammation plays a prominent role in the development of atherosclerosis, which is the most important risk factor for vascular events. Lymphotoxin-alpha (LTA)…”
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Can the clinical efficacy of the HMG CoA reductase inhibitors be explained solely by their effects on LDL-cholesterol? by Gaw, Allan

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