Search Results - "Gavlock, Dillon C."

Comparison of wild-type and high-risk PNPLA3 variants in a human biomimetic liver microphysiology system for metabolic dysfunction-associated steatotic liver disease precision therapy by Xia, Mengying, Varmazyad, Mahboubeh, Pla-Palacín, Iris, Gavlock, Dillon C, DeBiasio, Richard, LaRocca, Gregory, Reese, Celeste, Florentino, Rodrigo M, Faccioli, Lanuza A P, Brown, Jacquelyn A, Vernetti, Lawrence A, Schurdak, Mark, Stern, Andrew M, Gough, Albert, Behari, Jaideep, Soto-Gutierrez, Alejandro, Taylor, D Lansing, Miedel, Mark T

“…Metabolic dysfunction-associated steatotic liver disease (MASLD) is a worldwide health epidemic with a global occurrence of approximately 30%. The pathogenesis…”
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Human induced pluripotent stem cell based hepatic-modeling of lipid metabolism associated TM6SF2 E167K variant by Faccioli, Lanuza Ap, Sun, Yiyue, Animasahun, Olamide, Motomura, Takashi, Liu, Zhenghao, Kurihara, Takeshi, Hu, Zhiping, Yang, Bo, Cetin, Zeliha, Baratta, Annalisa M, Shankaran, Ajay, Nenwani, Minal, Altay, Leyla Nurcihan, Huang, Linqi, Meurs, Noah, Franks, Jonathan, Stolz, Donna, Gavlock, Dillon C, Miedel, Mark T, Ostrowska, Alina, Florentino, Rodrigo M, Fox, Ira J, Nagrath, Deepak, Soto-Gutierrez, Alejandro

“…TM6SF2 rs58542926 (E167K) is related to increased prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD). Conflicting mouse study…”
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Modeling the Effect of the Metastatic Microenvironment on Phenotypes Conferred by Estrogen Receptor Mutations Using a Human Liver Microphysiological System by Miedel, Mark T., Gavlock, Dillon C., Jia, Shanhang, Gough, Albert, Taylor, D. Lansing, Stern, Andrew M.

“…Reciprocal coevolution of tumors and their microenvironments underlies disease progression, yet intrinsic limitations of patient-derived xenografts and simpler…”
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