Search Results - "Gavis, Elizabeth R."

Plasticity of Drosophila germ granules during germ cell development by Hakes, Anna C, Gavis, Elizabeth R

“…Compartmentalization of RNAs and proteins into membraneless structures called granules is a ubiquitous mechanism for organizing and regulating cohorts of RNAs…”
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Localization of oskar mRNA by agglomeration in ribonucleoprotein granules by Eichler, Catherine E, Li, Hui, Grunberg, Michelle E, Gavis, Elizabeth R

“…Localization of oskar mRNA to the posterior of the Drosophila oocyte is essential for abdominal patterning and germline development. oskar localization is a…”
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Ribosome profiling reveals pervasive and regulated stop codon readthrough in Drosophila melanogaster by Dunn, Joshua G, Foo, Catherine K, Belletier, Nicolette G, Gavis, Elizabeth R, Weissman, Jonathan S

“…Ribosomes can read through stop codons in a regulated manner, elongating rather than terminating the nascent peptide. Stop codon readthrough is essential to…”
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Transport of Germ Plasm on Astral Microtubules Directs Germ Cell Development in Drosophila by Lerit, Dorothy A., Gavis, Elizabeth R.

“…In many organisms, germ cells are segregated from the soma through the inheritance of the specialized germ plasm, which contains mRNAs and proteins that…”
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Lighting up mRNA localization in Drosophila oogenesis by Becalska, Agata N, Gavis, Elizabeth R

“…The asymmetric localization of four maternal mRNAs - gurken, bicoid, oskar and nanos - in the Drosophila oocyte is essential for the development of the…”
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Fixed and live visualization of RNAs in Drosophila oocytes and embryos by Abbaszadeh, Evan K., Gavis, Elizabeth R.

“…•smFISH and genetically encoded fluorescent RNA tagging provide complementary tools to visualize RNA in situ.•smFISH provides quantitative detection of…”
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The translational repressor Glorund uses interchangeable RNA recognition domains to recognize Drosophila nanos by Warden, Meghan S, DeRose, Eugene F, Tamayo, Joel V, Mueller, Geoffrey A, Gavis, Elizabeth R, Hall, Traci M Tanaka

“…Abstract The Drosophila melanogaster protein Glorund (Glo) represses nanos (nos) translation and uses its quasi-RNA recognition motifs (qRRMs) to recognize…”
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Compartmentalized oskar degradation in the germ plasm safeguards germline development by Eichler, Catherine E, Hakes, Anna C, Hull, Brooke, Gavis, Elizabeth R

“…Partitioning of mRNAs into ribonucleoprotein (RNP) granules supports diverse regulatory programs within the crowded cytoplasm. At least two types of RNP…”
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The ELAV/Hu protein Found in neurons regulates cytoskeletal and ECM adhesion inputs for space-filling dendrite growth by Alizzi, Rebecca A, Xu, Derek, Tenenbaum, Conrad M, Wang, Wei, Gavis, Elizabeth R

“…Dendritic arbor morphology influences how neurons receive and integrate extracellular signals. We show that the ELAV/Hu family RNA-binding protein Found in…”
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Enclosure of Dendrites by Epidermal Cells Restricts Branching and Permits Coordinated Development of Spatially Overlapping Sensory Neurons by Tenenbaum, Conrad M., Misra, Mala, Alizzi, Rebecca A., Gavis, Elizabeth R.

“…Spatial arrangement of different neuron types within a territory is essential to neuronal development and function. How development of different neuron types…”
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Specific Localization of the Drosophila Telomere Transposon Proteins and RNAs, Give Insight in Their Behavior, Control and Telomere Biology in This Organism by López-Panadès, Elisenda, Gavis, Elizabeth R, Casacuberta, Elena

“…Drosophila telomeres constitute a remarkable exception to the telomerase mechanism. Although maintaining the same cytological and functional properties as…”
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Germ Plasm Anchoring Is a Dynamic State that Requires Persistent Trafficking by Sinsimer, Kristina S., Lee, Jack J., Thiberge, Stephan Y., Gavis, Elizabeth R.

“…Localized cytoplasmic determinants packaged as ribonucleoprotein (RNP) particles direct embryonic patterning and cell fate specification in a wide range of…”
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Localization of bicoid mRNA in Late Oocytes Is Maintained by Continual Active Transport by Weil, Timothy T., Forrest, Kevin M., Gavis, Elizabeth R.

“…Localization of bicoid mRNA to the anterior of the Drosophila oocyte is essential to produce the Bicoid protein gradient that patterns the anterior-posterior…”
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Regional Modulation of a Stochastically Expressed Factor Determines Photoreceptor Subtypes in the Drosophila Retina by Thanawala, Shivani U., Rister, Jens, Goldberg, Gregory W., Zuskov, Andrey, Olesnicky, Eugenia C., Flowers, Jonathan M., Jukam, David, Purugganan, Michael D., Gavis, Elizabeth R., Desplan, Claude, Johnston, Robert J.

“…Stochastic mechanisms are sometimes utilized to diversify cell fates, especially in nervous systems. In the Drosophila retina, stochastic expression of the…”
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bicoid mRNA localises to the Drosophila oocyte anterior by random Dynein-mediated transport and anchoring by Trovisco, Vítor, Belaya, Katsiaryna, Nashchekin, Dmitry, Irion, Uwe, Sirinakis, George, Butler, Richard, Lee, Jack J, Gavis, Elizabeth R, St Johnston, Daniel

“…mRNA localises to the oocyte anterior from stage 9 of oogenesis onwards to provide a local source for Bicoid protein for embryonic patterning. Live imaging at…”
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Removal of Drosophila Muscle Tissue from Larval Fillets for Immunofluorescence Analysis of Sensory Neurons and Epidermal Cells by Tenenbaum, Conrad M, Gavis, Elizabeth R

“…Drosophila larval dendritic arborization (da) neurons are a popular model for investigating mechanisms of neuronal morphogenesis. Da neurons develop in…”
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Germ Cell-less Promotes Centrosome Segregation to Induce Germ Cell Formation by Lerit, Dorothy A., Shebelut, Conrad W., Lawlor, Kristen J., Rusan, Nasser M., Gavis, Elizabeth R., Schedl, Paul, Deshpande, Girish

“…The primordial germ cells (PGCs) specified during embryogenesis serve as progenitors to the adult germline stem cells. In Drosophila, the proper specification…”
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Spatial Regulation of nanos Is Required for Its Function in Dendrite Morphogenesis by Brechbiel, Jillian L., Gavis, Elizabeth R.

“…Spatial control of mRNA translation can generate cellular asymmetries and functional specialization of polarized cells like neurons. A requirement for the…”
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A late phase of germ plasm accumulation during Drosophila oogenesis requires lost and rumpelstiltskin by Sinsimer, Kristina S, Jain, Roshan A, Chatterjee, Seema, Gavis, Elizabeth R

“…Asymmetric mRNA localization is an effective mechanism for establishing cellular and developmental polarity. Posterior localization of oskar in the Drosophila…”
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The Drosophila hnRNP F/H Homolog Glorund Uses Two Distinct RNA-Binding Modes to Diversify Target Recognition by Tamayo, Joel V., Teramoto, Takamasa, Chatterjee, Seema, Hall, Traci M. Tanaka, Gavis, Elizabeth R.

“…The Drosophila hnRNP F/H homolog, Glorund (Glo), regulates nanos mRNA translation by interacting with a structured UA-rich motif in the nanos 3′ untranslated…”
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