Search Results - "Gavioli, Riccardo"

Impaired Priming of SARS-CoV-2-Specific Naive CD8+ T Cells in Older Subjects by Gallerani, Eleonora, Proietto, Davide, Dallan, Beatrice, Campagnaro, Marco, Pacifico, Salvatore, Albanese, Valentina, Marzola, Erika, Marconi, Peggy, Caputo, Antonella, Appay, Victor, Gavioli, Riccardo, Nicoli, Francesco

“…Advanced age is associated with severe symptoms and death upon SARS-CoV-2 infection. Virus-specific CD8 + T-cell responses have shown to be protective toward…”
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Age-related decline of de novo T cell responsiveness as a cause of COVID-19 severity by Nicoli, Francesco, Solis-Soto, Maria Teresa, Paudel, Deepak, Marconi, Peggy, Gavioli, Riccardo, Appay, Victor, Caputo, Antonella

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Rational Design of Nucleoside-Bile Acid Conjugates Incorporating a Triazole Moiety for Anticancer Evaluation and SAR Exploration by Navacchia, Maria Luisa, Marchesi, Elena, Mari, Lara, Chinaglia, Nicola, Gallerani, Eleonora, Gavioli, Riccardo, Capobianco, Massimo Luigi, Perrone, Daniela

“…Herein we report a study on the synthesis and biological evaluation of a library of nucleoside-bile acid conjugates prepared by combining 2'-deoxyadenosine,…”
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Effects of the age of vaccination on the humoral responses to a human papillomavirus vaccine by Nicoli, Francesco, Mantelli, Barbara, Gallerani, Eleonora, Telatin, Valentina, Squarzon, Laura, Masiero, Serena, Gavioli, Riccardo, Palù, Giorgio, Barzon, Luisa, Caputo, Antonella

“…Adult vaccination programs are receiving increasing attention however, little is known regarding the impact of age on the maintenance of the immune response…”
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The HIV-1 Tat protein induces the activation of CD8+ T cells and affects in vivo the magnitude and kinetics of antiviral responses by Nicoli, Francesco, Finessi, Valentina, Sicurella, Mariaconcetta, Rizzotto, Lara, Gallerani, Eleonora, Destro, Federica, Cafaro, Aurelio, Marconi, Peggy, Caputo, Antonella, Ensoli, Barbara, Gavioli, Riccardo

“…T cells are functionally compromised during HIV infection despite their increased activation and proliferation. Although T cell hyperactivation is one of the…”
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New Scaffolds of Proteasome Inhibitors: Boosting Anticancer Potential by Exploiting the Synergy of In Silico and In Vitro Methodologies by Guedes, Romina A, Grilo, Jorge H, Carvalho, Andreia N, Fernandes, Pedro M. P, Ressurreição, Ana S, Brito, Vanessa, Santos, Adriana O, Silvestre, Samuel, Gallerani, Eleonora, Gama, Maria João, Gavioli, Riccardo, Salvador, Jorge A. R, Guedes, Rita C

“…Cancer is a complex multifactorial disease whose pathophysiology involves multiple metabolic pathways, including the ubiquitin–proteasome system, for which…”
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Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors by Marastoni, Mauro, Trapella, Claudio, Scotti, Alessandra, Fantinati, Anna, Ferretti, Valeria, Marzola, Erika, Eleonora, Gallerani, Gavioli, Riccardo, Preti, Delia

“…The ubiquitin-proteasome system has been largely investigated for its key role in protein degradation mechanisms that regulate both apoptosis and cell…”
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Ageing Curtails the Diversity and Functionality of Nascent CD8 + T Cell Responses against SARS-CoV-2 by Proietto, Davide, Dallan, Beatrice, Gallerani, Eleonora, Albanese, Valentina, Llewellyn-Lacey, Sian, Price, David A, Appay, Victor, Pacifico, Salvatore, Caputo, Antonella, Nicoli, Francesco, Gavioli, Riccardo

“…Age-related changes in the immune system are thought to underlie the vulnerability of elderly individuals to emerging viral diseases, such as coronavirus…”
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A New Approach to UV Protection by Direct Surface Functionalization of TiO2 with the Antioxidant Polyphenol Dihydroxyphenyl Benzimidazole Carboxylic Acid by Battistin, Mattia, Dissette, Valeria, Bonetto, Alessandro, Durini, Elisa, Manfredini, Stefano, Marcomini, Antonio, Casagrande, Elisa, Brunetta, Andrea, Ziosi, Paola, Molesini, Sonia, Gavioli, Riccardo, Nicoli, Francesco, Vertuani, Silvia, Baldisserotto, Anna

“…Skin cancer is the most common malignant cancer with an incidence of 1 million cases/year. It is well known that exposure to UV radiation from sunlight leads…”
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HPV-Specific Systemic Antibody Responses and Memory B Cells are Independently Maintained up to 6 Years and in a Vaccine-Specific Manner Following Immunization with Cervarix and Gardasil in Adolescent and Young Adult Women in Vaccination Programs in Italy by Nicoli, Francesco, Mantelli, Barbara, Gallerani, Eleonora, Telatin, Valentina, Bonazzi, Irene, Marconi, Peggy, Gavioli, Riccardo, Gabrielli, Liliana, Lazzarotto, Tiziana, Barzon, Luisa, Palù, Giorgio, Caputo, And Antonella

“…Human papillomavirus (HPV) persistent infections are associated with cervical cancer and other HPV-related diseases and tumors. Thus, the characterization of…”
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Focus group study on perceptions and information needs regarding vaccines targeting the older population: a cross-country comparison in four European countries by Wennekes, Manuela Dominique, Eilers, Renske, Caputo, Antonella, Gagneux-Brunon, Amandine, Gavioli, Riccardo, Nicoli, Francesco, Vokó, Zoltán, Timen, Aura

“…The increasing life expectancy leads to more older adults suffering from infectious diseases. Vaccines are available against diverse infections such as…”
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An attenuated herpes simplex virus type 1 (HSV1) encoding the HIV-1 Tat protein protects mice from a deadly mucosal HSV1 challenge by Sicurella, Mariaconcetta, Nicoli, Francesco, Gallerani, Eleonora, Volpi, Ilaria, Berto, Elena, Finessi, Valentina, Destro, Federica, Manservigi, Roberto, Cafaro, Aurelio, Ensoli, Barbara, Caputo, Antonella, Gavioli, Riccardo, Marconi, Peggy C

“…Herpes simplex virus types 1 and 2 (HSV1 and HSV2) are common infectious agents in both industrialized and developing countries. They cause recurrent…”
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Stressing the ubiquitin-proteasome system without 20S proteolytic inhibition selectively kills cervical cancer cells by Anchoori, Ravi K, Khan, Saeed R, Sueblinvong, Thanasak, Felthauser, Alicia, Iizuka, Yoshie, Gavioli, Riccardo, Destro, Federica, Isaksson Vogel, Rachel, Peng, Shiwen, Roden, Richard B S, Bazzaro, Martina

“…Cervical cancer cells exhibit an increased requirement for ubiquitin-dependent protein degradation associated with an elevated metabolic turnover rate, and for…”
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The Tat Protein of HIV-1 Prevents the Loss of HSV-Specific Memory Adaptive Responses and Favors the Control of Viral Reactivation by Nicoli, Francesco, Gallerani, Eleonora, Sicurella, Mariaconcetta, Pacifico, Salvatore, Cafaro, Aurelio, Ensoli, Barbara, Marconi, Peggy, Caputo, Antonella, Gavioli, Riccardo

“…The development of therapeutic strategies to control the reactivation of the Herpes Simplex Virus (HSV) is an unaddressed priority. In this study, we evaluated…”
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Time Trend Analysis of Tuberculosis Treatment While Using Digital Adherence Technologies-An Individual Patient Data Meta-Analysis of Eleven Projects across Ten High Tuberculosis-Burden Countries by de Groot, Liza M, Straetemans, Masja, Maraba, Noriah, Jennings, Lauren, Gler, Maria Tarcela, Marcelo, Danaida, Mekoro, Mirchaye, Steenkamp, Pieter, Gavioli, Riccardo, Spaulding, Anne, Prophete, Edwin, Bury, Margarette, Banu, Sayera, Sultana, Sonia, Onjare, Baraka, Efo, Egwuma, Alacapa, Jason, Levy, Jens, Morales, Mona Lisa L, Katamba, Achilles, Bogdanov, Aleksey, Gamazina, Kateryna, Kumarkul, Dzhumagulova, Ekaterina, Orechova-Li, Cattamanchi, Adithya, Khan, Amera, Bakker, Mirjam I

“…Worldwide, non-adherence to tuberculosis (TB) treatment is problematic. Digital adherence technologies (DATs) offer a person-centered approach to support and…”
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Use of a Novel Peptide Welding Technology Platform for the Development of B- and T-Cell Epitope-Based Vaccines by Nicoli, Francesco, Pacifico, Salvatore, Gallerani, Eleonora, Marzola, Erika, Albanese, Valentina, Finessi, Valentina, Llewellyn-Lacey, Sian, Price, David A., Appay, Victor, Marconi, Peggy, Guerrini, Remo, Caputo, Antonella, Gavioli, Riccardo

“…Peptide vaccines incorporating B- and T-cell epitopes have shown promise in the context of various cancers and infections. These vaccines are relatively simple…”
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Nafion®-Containing Solid Lipid Nanoparticles as a Tool for Anticancer Pt Delivery: Preliminary Studies by Bergamini, Paola, Cortesi, Rita, Mariani, P., Gavioli, Riccardo, Gallerani, Eleonora, Drechsler, Marcus, Esposito, Elisabetta, Sguizzato, Maddalena, Carducci, Federica

“…Preliminary studies of nanoparticles based on the perfluorosulfonic acid resin Nafion have been carried out with the aim of establishing an ionic connection…”
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Expression of A3 adenosine receptors in human lymphocytes: up-regulation in T cell activation by Gessi, Stefania, Varani, Katia, Merighi, Stefania, Cattabriga, Elena, Avitabile, Arianna, Gavioli, Riccardo, Fortini, Cinzia, Leung, Edward, Mac Lennan, Stephen, Borea, Pier Andrea

“…The present study investigates mRNA and protein levels of A3 adenosine receptors in resting (R) and activated (A) human lymphocytes. The receptors were…”
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c- myc overexpression activates alternative pathways for intracellular proteolysis in lymphoma cells by Masucci, Maria G, Gavioli, Riccardo, Frisan, Teresa, Vertuani, Simona, Bornkamm, Georg W

“…Burkitt's lymphoma (BL) is a highly malignant B-cell tumour characterized by chromosomal translocations that constitutively activate the c-myc oncogene. Here…”
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The Toll‐like receptor ligand MALP‐2 stimulates dendritic cell maturation and modulates proteasome composition and activity by Link, Claudia, Gavioli, Riccardo, Ebensen, Thomas, Canella, Alessandro, Reinhard, Elena, Guzmán, Carlos A.

“…A 2‐kDa synthetic derivative of the macrophage‐activating lipopeptide (MALP‐2) from Mycoplasma fermentans is a potent inducer of monocytes/macrophages and…”
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