Search Results - "Gavin, William G"

Adeno-associated virus (AAV)-mediated transduction of male germ line stem cells results in transgene transmission after germ cell transplantation by Honaramooz, Ali, Megee, Susan, Zeng, Wenxian, Destrempes, Margret M, Overton, Susan A, Luo, Jinping, Galantino-Homer, Hannah, Modelski, Mark, Chen, Fangping, Blash, Stephen, Melican, David T, Gavin, William G, Ayres, Sandra, Yang, Fang, Wang, P. Jeremy, Echelard, Yann, Dobrinski, Ina

“…We explored whether exposure of mammalian germ line stem cells to adeno-associated virus (AAV), a gene therapy vector, would lead to stable transduction and…”
Get full text

Transgenic goats producing an improved version of cetuximab in milk by Laible, Götz, Cole, Sally, Brophy, Brigid, Maclean, Paul, How Chen, Li, Pollock, Dan P., Cavacini, Lisa, Fournier, Nathalie, De Romeuf, Christophe, Masiello, Nicholas C., Gavin, William G., Wells, David N., Meade, Harry M.

“…Therapeutic monoclonal antibodies (mAbs) represent one of the most important classes of pharmaceutical proteins to treat human diseases. Most are produced in…”
Get full text

Production of recombinant albumin by a herd of cloned transgenic cattle by Echelard, Yann, Williams, Jennifer L, Destrempes, Margaret M, Koster, Julie A, Overton, Susan A, Pollock, Daniel P, Rapiejko, Karen T, Behboodi, Esmail, Masiello, Nicholas C, Gavin, William G, Pommer, Jerry, Van Patten, Scott M, Faber, David C, Cibelli, Jose B, Meade, Harry M

“…Purified plasma derived human albumin has been available as a therapeutic product since World War II. However, cost effective recombinant production of albumin…”
Get full text

Induction of parturition in a large number of pregnant dairy goats and its benefits as a management tool in a commercial scale goat operation by Pollock, John M., Miner, Kerry, Buzzell, Nathan, Schofield, Michael, Hawkins, Nathan, Blash, Stephen, Barton, Bruce, Gavin, William G.

“…At LFB USA, Inc., transgenic goats are utilized for the production of recombinant human protein therapeutics in their milk through the rPRO™ Technology…”
Get full text

Johne’s disease: a successful eradication programme in a dairy goat herd by Gavin, William G, Porter, Catherine A, Hawkins, Nathan, Schofield, Michael J, Pollock, John M

“…This retrospective analysis and report describes the successful eradication and posteradication surveillance programme for Johne’s disease (Mycobacterium avium…”
Get full text

Competitive-inhibition enzyme-linked immunosorbent assay for detection of serum antibodies to caprine arthritis-encephalitis virus: diagnostic tool for successful eradication by Herrmann, Lynn M, Cheevers, William P, McGuire, Travis C, Adams, D Scott, Hutton, Melinda M, Gavin, William G, Knowles, Donald P

“…A competitive-inhibition enzyme-linked immunosorbent assay (cELISA) was evaluated for the detection of serum antibodies to the surface envelope (SU) of caprine…”
Get full text

Production of goats by somatic cell nuclear transfer by Baguisi, A, Behboodi, E, Melican, D.T, Pollock, J.S, Destrempes, M.M, Cammuso, C, Williams, J.L, Nims, S.D, Porter, C.A, Midura, P

“…In this study, we demonstrate the production of transgenic goats by nuclear transfer of fetal somatic cells. Donor karyoplasts were obtained from a primary…”
Get full text

Neospora caninum: A successful testing and eradication program in a dairy goat herd by Altbuch, Jennifer A., Schofield, Michael J., Porter, Catherine A., Gavin, William G.

“…This report describes the detection and epidemiology of Neospora caninum (N. caninum) within a closed dairy goat herd and the successful eradication and…”
Get full text

Cloned Transgenic Offspring Resulting from Somatic Cell Nuclear Transfer in the Goat: Oocytes Derived from Both Follicle-Stimulating Hormone-Stimulated and Nonstimulated Abattoir-Derived Ovaries1 by Reggio, Brett C, James, Aidita N, Green, Heather L, Gavin, William G, Behboodi, Esmail, Echelard, Yann, Godke, Robert A

“…The use of nuclear transfer (NT) techniques to create transgenic offspring capable of producing valuable proteins may have a major impact on the pharmaceutical…”
Get full text

Cloned Transgenic Offspring Resulting from Somatic Cell Nuclear Transfer in the Goat: Oocytes Derived from Both Follicle-Stimulating Hormone-Stimulated and Nonstimulated Abattoir-Derived Ovaries by REGGIO, Brett C, JAMES, Aidita N, GREEN, Heather L, GAVIN, William G, BEHBOODI, Esmail, ECHELARD, Yann, GODKE, Robert A

“…The use of nuclear transfer (NT) techniques to create transgenic offspring capable of producing valuable proteins may have a major impact on the pharmaceutical…”
Get full text

Goat embryonic stem-like cell derivation and characterization by Behboodi, Esmail, Lam, Louise, Gavin, William G, Bondareva, Alla, Dobrinski, Ina

“…Embryonic stem (ES) cells are derived from the inner cell masses of preimplantation embryos. ES cells are pluripotent cells with the capacity for long-term…”
Get more information

Viable transgenic goats derived from skin cells by Behboodi, E, Memili, E, Melican, D.T, Destrempes, M.M, Overton, S.A, Williams, J.L, Flanagan, P.A, Butler, R.E, Liem, H, Chen, L.H

“…The current study was undertaken to evaluate the possibility of expanding transgenic goat herds by means of somatic cell nuclear transfer (NT) using transgenic…”
Get full text

Reestablishment of a transgenic rabbit line by artificial insemination using cryopreserved semen by Blash, Stephen, Chen, Lihow, Harvey, Merry, Gavin, William G

“…The production of recombinant proteins in the milk of transgenic animals is an alternative to traditional cell culture methodology. Transgenic rabbits can…”
Get full text

Caprine herpesvirus 1: A successful eradication program in dairy goat herd by Pollock, John M., Schofield, Michael J., Porter, Catherine, Miner, Kerry, Blash, Stephen, Gavin, William G.

“…•Caprine herpesvirus 1: a successful eradication program in a dairy goat herd.•Serum neutralization assay was a useful screening test for caprine herpesvirus…”
Get full text

TG20, a Transgenically-Derived Anti-CD20 Monoclonal Antibody, Exhibits Enhanced Cytotoxicity Against Cells with Low Levels of CD20 by Echelard, Yann, Pollock, Daniel P., Coupade, Catherine De, Olivier, Aurélie Groseil, Brune, Frédérique, Chen, LiHow, Masiello, Nicholas C., Williams, Jennifer L., Gavin, William G., Chtourou, Sami, Meade, Harry M.

“…Abstract 2730 CD20 is a cell-surface glycoprotein that is highly expressed on most B-cells, tightly restricted to the B-cell lineage, and not expressed on…”
Get full text