Search Results - "Gavilán, Elena"

MMP1 drives tumor progression in large cell carcinoma of the lung through fibroblast senescence by Gabasa, Marta, Radisky, Evette S., Ikemori, Rafael, Bertolini, Giulia, Arshakyan, Marselina, Hockla, Alexandra, Duch, Paula, Rondinone, Ornella, Llorente, Alejandro, Maqueda, Maria, Davalos, Albert, Gavilán, Elena, Perera, Alexandre, Ramírez, Josep, Gascón, Pere, Reguart, Noemí, Roz, Luca, Radisky, Derek C., Alcaraz, Jordi

“…Large cell carcinoma (LCC) is a rare and aggressive lung cancer subtype with poor prognosis and no targeted therapies. Tumor-associated fibroblasts (TAFs)…”
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Protein Quality Control Systems and ER Stress as Key Players in SARS-CoV-2-Induced Neurodegeneration by Gavilán, Elena, Medina-Guzman, Rafael, Bahatyrevich-Kharitonik, Bazhena, Ruano, Diego

“…The COVID-19 pandemic has brought to the forefront the intricate relationship between SARS-CoV-2 and its impact on neurological complications, including…”
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Communication in Weighted Networks: A Game Theoretic Approach by Gavilán, Elena C., Manuel, Conrado, Martín, Daniel

“…In this paper we generalize the allocation rule (point solution or value) known as the mixed value by introducing the weighted mixed value.The proposed…”
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Neuroprotective effect of rice bran enzymatic extract-supplemented diets in a murine model of Parkinson's disease by Gavilán, Elena, Flores, Alicia, Castaño, Angélica, Martin-Presas, Luis, Bahatyrevich-Kharitonik, Bazhena, Medina-Guzman, Rafael, Parrado, Juan, Burguillos, Miguel Ángel

“…[Display omitted] •RBEE contains bioactive compounds, including γ-oryzanol, tocopherols and tocotrienols.•RBEE exhibits neuroprotection and decreases…”
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mTOR Inhibition and T-DM1 in HER2-Positive Breast Cancer by Casadevall, David, Hernández-Prat, Anna, García-Alonso, Sara, Arpí-Llucià, Oriol, Menéndez, Silvia, Qin, Mengjuan, Guardia, Cristina, Morancho, Beatriz, Sánchez-Martín, Francisco Javier, Zazo, Sandra, Gavilán, Elena, Sabbaghi, Mohammad A., Eroles, Pilar, Cejalvo, Juan Miguel, Lluch, Ana, Rojo, Federico, Pandiella, Atanasio, Rovira, Ana, Albanell, Joan

“…In patients with trastuzumab-resistant HER2-positive breast cancer, the combination of everolimus (mTORC1 inhibitor) with trastuzumab failed to show a…”
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Age-related dysfunctions of the autophagy lysosomal pathway in hippocampal pyramidal neurons under proteasome stress by Gavilán, Elena, Pintado, Cristina, Gavilan, Maria P, Daza, Paula, Sánchez-Aguayo, Inmaculada, Castaño, Angélica, Ruano, Diego

“…Abstract Autophagy plays a key role in the maintenance of cellular homeostasis, and autophagy deregulation gives rise to severe disorders. Many of the…”
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Breast cancer cell line MCF7 escapes from G1/S arrest induced by proteasome inhibition through a GSK-3β dependent mechanism by Gavilán, Elena, Giráldez, Servando, Sánchez-Aguayo, Inmaculada, Romero, Francisco, Ruano, Diego, Daza, Paula

“…Targeting the ubiquitin proteasome pathway has emerged as a rational approach in the treatment of human cancers. Autophagy has been described as a…”
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Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus by Pintado, Cristina, Gavilán, María P, Gavilán, Elena, García-Cuervo, Luisa, Gutiérrez, Antonia, Vitorica, Javier, Castaño, Angélica, Ríos, Rosa M, Ruano, Diego

“…Neuroinflammation and protein accumulation are characteristic hallmarks of both normal aging and age-related neurodegenerative diseases. However, the…”
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A Family of Position Values for Directed Communication Situations by Gavilán, Elena C., Manuel, Conrado M., Van Den Brink, René

“…In this paper, we define a family of values for directed communication situations that are inspired by the position value. We use the concept of directed…”
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Dysfunction of the unfolded protein response increases neurodegeneration in aged rat hippocampus following proteasome inhibition by Paz Gavilán, María, Pintado, Cristina, Gavilán, Elena, Jiménez, Sebastián, Ríos, Rosa M., Vitorica, Javier, Castaño, Angélica, Ruano, Diego

“…Summary Dysfunctions of the ubiquitin proteasome system (UPS) have been proposed to be involved in the aetiology and/or progression of several age‐related…”
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Neuron specific toxicity of oligomeric amyloid-β: role for JUN-kinase and oxidative stress by Ebenezer, Philip J, Weidner, Adam M, LeVine, 3rd, Harry, Markesbery, William R, Murphy, M Paul, Zhang, Le, Dasuri, Kalavathi, Fernandez-Kim, Sun Ok, Bruce-Keller, Annadora J, Gavilán, Elena, Keller, Jeffrey N

“…Recent studies have demonstrated a potential role for oligomeric forms of amyloid-β (Aβ) in the pathogenesis of Alzheimer's disease (AD), although it remains…”
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Amino acid analog toxicity in primary rat neuronal and astrocyte cultures: Implications for protein misfolding and TDP-43 regulation by Dasuri, Kalavathi, Ebenezer, Philip J., Uranga, Romina M., Gavilán, Elena, Zhang, Le, Fernandez-Kim, Sun O.K., Bruce-Keller, Annadora J., Keller, Jeffrey N.

“…Amino acid analogs promote translational errors that result in aberrant protein synthesis and have been used to understand the effects of protein misfolding in…”
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Selective vulnerability of neurons to acute toxicity after proteasome inhibitor treatment: Implications for oxidative stress and insolubility of newly synthesized proteins by Dasuri, Kalavathi, Ebenezer, Philip J., Zhang, Le, Fernandez-Kim, Sun Ok, Uranga, Romina M., Gavilán, Elena, Di Blasio, Alessia, Keller, Jeffrey N.

“…Maintaining protein homeostasis is vital to cell viability, with numerous studies demonstrating a role for proteasome inhibition occurring during the aging of…”
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Learning improvement after PI3K activation correlates with de novo formation of functional small spines by Enriquez-Barreto, Lilian, Cuesto, Germán, Dominguez-Iturza, Nuria, Gavilán, Elena, Ruano, Diego, Sandi, Carmen, Fernández-Ruiz, Antonio, Martín-Vázquez, Gonzalo, Herreras, Oscar, Morales, Miguel

“…PI3K activation promotes the formation of synaptic contacts and dendritic spines, morphological features of glutamatergic synapses that are commonly known to…”
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Age-related differences in the dynamics of hippocampal proteasome recovery by Gavilán, M. Paz, Pintado, Cristina, Gavilán, Elena, García-Cuervo, Luisa M., Castaño, Angelica, Ríos, Rosa M., Ruano, Diego

“…Regulation of proteasome abundance to meet cell needs under stress conditions is critical for maintaining cellular homeostasis. However, the effects of aging…”
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Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer by Arena, Sabrina, Bellosillo, Beatriz, Siravegna, Giulia, Martínez, Alejandro, Cañadas, Israel, Lazzari, Luca, Ferruz, Noelia, Russo, Mariangela, Misale, Sandra, González, Iria, Iglesias, Mar, Gavilan, Elena, Corti, Giorgio, Hobor, Sebastijan, Crisafulli, Giovanni, Salido, Marta, Sánchez, Juan, Dalmases, Alba, Bellmunt, Joaquim, De Fabritiis, Gianni, Rovira, Ana, Di Nicolantonio, Federica, Albanell, Joan, Bardelli, Alberto, Montagut, Clara

“…Patients with colorectal cancer who respond to the anti-EGFR antibody cetuximab often develop resistance within several months of initiating therapy. To design…”
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Neuroprotective effect of rice bran enzymatic extract-supplemented diets in a murine model of Parkinsońs disease by Elena Gavilán, Alicia Flores, Angélica Castaño, Luis Martin-Presas, Bazhena Bahatyrevich-Kharitonik, Rafael Medina-Guzman, Juan Parrado, Miguel Ángel Burguillos

“…Neurodegenerative disorders such as Parkinson's disease, present a global health concern with limited therapeutic options. In this context, dietary…”
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Abstract P5-13-04: NF1 mutations render HER2+ breast cancer highly sensitive to T-DM1 by altering microtubule dynamics by Duso, Bruno A, Dorronzoro, Elena Gavilán, Tini, Giulia, de Filippo, Maria R, Bonetti, Emanuele, Ippolito, Maria R, Soriani, Chiara, D'Amico, Paolo, Rodighiero, Simona, Curigliano, Giuseppe, Santaguida, Stefano, Cristofanilli, Massimo, Pelicci, Pier Giuseppe, Mazzarella, Luca

“…Background: Despite major technological and conceptual advancements, treatment decisions in HER2+ metastatic breast cancer (mBC) remain largely based on…”
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Breast cancer cell line MCF7 escapes from G1/S arrest induced by proteasome inhibition through a GSK-3[beta] dependent mechanism by Gavilán, Elena, Giráldez, Servando, Sánchez-aguayo, Inmaculada, Romero, Francisco, Ruano, Diego, Daza, Paula

“…Targeting the ubiquitin proteasome pathway has emerged as a rational approach in the treatment of human cancers. Autophagy has been described as a…”
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Selective vulnerability of neurons to acute toxicity following proteasome inhibitor treatment: Implications for oxidative stress and insolubility of newly synthesized proteins by Dasuri, Kalavathi, Ebenezer, Philip J., Zhang, Le, Fernandez-Kim, Sun Ok, Uranga, Romina M., Gavilán, Elena, Di Blasio, Alessia, Keller, Jeffrey N

“…Maintaining protein homeostasis is vital to cell viability, with numerous studies demonstrating a role for proteasome inhibition occurring during the aging of…”
Get full text