Search Results - "Gavil, Noah V"

Responsiveness to interleukin-15 therapy is shared between tissue-resident and circulating memory CD8 + T cell subsets by Jarjour, Nicholas N, Wanhainen, Kelsey M, Peng, Changwei, Gavil, Noah V, Maurice, Nicholas J, Borges da Silva, Henrique, Martinez, Ryan J, Dalzell, Talia S, Huggins, Matthew A, Masopust, David, Hamilton, Sara E, Jameson, Stephen C

“…Interleukin-15 (IL-15) is often considered a central regulator of memory CD8 T cells, based primarily on studies of recirculating subsets. However, recent work…”
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Depleting CD103+ resident memory T cells in vivo reveals immunostimulatory functions in oral mucosa by Stolley, J Michael, Scott, Milcah C, Joag, Vineet, Dale, Alexander J, Johnston, Timothy S, Saavedra, Flavia, Gavil, Noah V, Lotfi-Emran, Sahar, Soerens, Andrew G, Weyu, Eyob, Pierson, Mark J, Herzberg, Mark C, Zhang, Nu, Vezys, Vaiva, Masopust, David

“…The oral mucosa is a frontline for microbial exposure and juxtaposes several unique tissues and mechanical structures. Based on parabiotic surgery of mice…”
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Adoptive lymphocyte transfer to an HIV-infected progressor from an elite controller by Migueles, Stephen A, Chairez, Cheryl, Lin, Siying, Gavil, Noah V, Rosenthal, Danielle M, Pooran, Milad, Natarajan, Ven, Rupert, Adam, Dewar, Robin, Rehman, Tauseef, Sherman, Brad T, Adelsberger, Joseph, Leitman, Susan F, Stroncek, David, Morse, Caryn G, Connors, Mark, Lane, H Clifford, Kovacs, Joseph A

“…BACKGROUNDHIV-infected patients with poor virologic control and multidrug-resistant virus have limited therapeutic options. The current study was undertaken to…”
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Functional virus-specific memory T cells survey glioblastoma by Ning, Jianfang, Gavil, Noah V., Wu, Shaoping, Wijeyesinghe, Sathi, Weyu, Eyob, Ma, Jun, Li, Ming, Grigore, Florina-Nicoleta, Dhawan, Sanjay, Skorput, Alexander G. J., Musial, Shawn C., Chen, Clark C., Masopust, David, Rosato, Pamela C.

“…Glioblastoma multiforme (GBM) is among the most aggressive, treatment-resistant cancers, and despite standard of care surgery, radiation and chemotherapy, is…”
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Cutting Edge: Mouse SARS-CoV-2 Epitope Reveals Infection and Vaccine-Elicited CD8 T Cell Responses by Joag, Vineet, Wijeyesinghe, Sathi, Stolley, J Michael, Quarnstrom, Clare F, Dileepan, Thamotharampillai, Soerens, Andrew G, Sangala, Jules A, O'Flanagan, Stephen D, Gavil, Noah V, Hong, Sung-Wook, Bhela, Siddheshvar, Gangadhara, Sailaja, Weyu, Eyob, Matchett, William E, Thiede, Joshua, Krishna, Venkatramana, Cheeran, Maxim C-J, Bold, Tyler D, Amara, Rama, Southern, Peter, Hart, Geoffrey T, Schifanella, Luca, Vezys, Vaiva, Jenkins, Marc K, Langlois, Ryan A, Masopust, David

“…The magnitude of SARS-CoV-2-specific T cell responses correlates inversely with human disease severity, suggesting T cell involvement in primary control…”
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HIV vaccines induce CD8 + T cells with low antigen receptor sensitivity by Migueles, Stephen A, Nettere, Danielle M, Gavil, Noah V, Wang, Lawrence T, Toulmin, Sushila A, Kelly, Elizabeth P, Ward, Addison J, Lin, Siying, Thompson, Sarah A, Peterson, Bennett A, Abdeen, Cassidy S, Sclafani, Carina R, Pryal, Patrick F, Leach, Benjamin G, Ludwig, Amanda K, Rogan, Daniel C, Przygonska, Paulina A, Cattani, Angela, Imamichi, Hiromi, Sachs, Abraham, Cafri, Gal, Huang, Ning-Na, Patamawenu, Andy, Liang, C Jason, Hallahan, Claire W, Kambach, Diane M, Han, Edward X, Coupet, Tiffany, Chen, Jonathan, Moir, Susan L, Chun, Tae-Wook, Coates, Emily E, Ledgerwood, Julie, Schmidt, Julien, Taillandier-Coindard, Marie, Michaux, Justine, Pak, HuiSong, Bassani-Sternberg, Michal, Frahm, Nicole, McElrath, M Juliana, Connors, Mark

“…Current HIV vaccines designed to stimulate CD8 T cells have failed to induce immunologic control upon infection. The functions of vaccine-induced HIV-specific…”
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Correction to: Functional virus‑specific memory T cells survey glioblastoma by Ning, Jianfang, Gavil, Noah V., Wu, Shaoping, Wijeyesinghe, Sathi, Weyu, Eyob, Ma, Jun, Li, Ming, Grigore, Florina‑Nicoleta, Dhawan, Sanjay, Skorput, Alexander G. J., Musial, Shawn C., Chen, Clark C., Masopust, David, Rosato, Pamela C.

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Antigenic Restimulation of Virus-Specific Memory CD8 + T Cells Requires Days of Lytic Protein Accumulation for Maximal Cytotoxic Capacity by Migueles, Stephen A, Rogan, Daniel C, Gavil, Noah V, Kelly, Elizabeth P, Toulmin, Sushila A, Wang, Lawrence T, Lack, Justin, Ward, Addison J, Pryal, Patrick F, Ludwig, Amanda K, Medina, Renata G, Apple, Benjamin J, Toumanios, Christina N, Poole, April L, Rehm, Catherine A, Jones, Sara E, Liang, C Jason, Connors, Mark

“…In various infections or vaccinations of mice or humans, reports of the persistence and the requirements for restimulation of the cytotoxic mediators granzyme…”
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Chronic antigen in solid tumors drives a distinct program of T cell residence by Gavil, Noah V, Scott, Milcah C, Weyu, Eyob, Smith, Olivia C, O'Flanagan, Stephen D, Wijeyesinghe, Sathi, Lotfi-Emran, Sahar, Shiao, Stephen L, Vezys, Vaiva, Masopust, David

“…Analyses of healthy tissue reveal signatures that identify resident memory CD8 T cells (T ), which survey tissues without recirculating. The density of T…”
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Mouse SARS-CoV-2 epitope reveals infection and vaccine-elicited CD8 T cell responses by Joag, Vineet, Wijeyesinghe, Sathi, Stolley, J. Michael, Quarnstrom, Clare F., Dileepan, Thamotharampillai, Soerens, Andrew G., Sangala, Jules A., O’Flanagan, Stephen D., Gavil, Noah V., Hong, Sung-Wook, Bhela, Siddheshvar, Gangadhara, Sailaja, Weyu, Eyob, Matchett, William, Thiede, Joshua, Krishna, Venkatramana, Cheeran, Maxim C-J., Bold, Tyler, Amara, Rama, Southern, Peter, Hart, Geoffrey T., Schifanella, Luca, Vezys, Vaiva, Jenkins, Marc K., Langlois, Ryan A., Masopust, David

“…The magnitude of SARS-CoV-2-specific T cell responses correlates inversely with human disease severity, suggesting T cell involvement in primary control. While…”
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