Search Results - "Gava, Agata L."

Increased ROS production and DNA damage in monocytes are biomarkers of aging and atherosclerosis by Jacinto, Thais A, Meireles, Giselle S, Dias, Ananda T, Aires, Rafaela, Porto, Marcella L, Gava, Agata L, Vasquez, Elisardo C, Pereira, Thiago Melo C, Campagnaro, Bianca P, Meyrelles, Silvana S

“…New evidence demonstrates that aging and dyslipidemia are closely associated with oxidative stress, DNA damage and apoptosis in some cells and extravascular…”
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Sildenafil restores endothelial function in the apolipoprotein E knockout mouse by Balarini, Camille M, Leal, Marcos A, Gomes, Isabele B S, Pereira, Thiago M C, Gava, Agata L, Meyrelles, Silvana S, Vasquez, Elisardo C

“…Atherosclerosis is an inflammatory process of the arterial walls and is initiated by endothelial dysfunction accompanied by an imbalance in the production of…”
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Novel Therapeutic Targets for Phosphodiesterase 5 Inhibitors: current state-of-the-art on systemic arterial hypertension and atherosclerosis by Vasquez, Elisardo C, Gava, Agata L, Graceli, Jones B, Balarini, Camille M, Campagnaro, Bianca P, Pereira, Thiago Melo C, Meyrelles, Silvana S

“…The usefulness of selective inhibitors of phosphodiesterase 5 (PDE5) is well known, first for the treatment of male erectile dysfunction and more recently for…”
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Cardiac and vascular phenotypes in the apolipoprotein E-deficient mouse by Vasquez, Elisardo C, Peotta, Veronica A, Gava, Agata L, Pereira, Thiago Mc, Meyrelles, Silvana S

“…Cardiovascular death is frequently associated with atherosclerosis, a chronic multifactorial disease and a leading cause of death worldwide. Genetically…”
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Sildenafil (Viagra®) Prevents Cox-1/ TXA2 Pathway-Mediated Vascular Hypercontractility in ApoE-/- Mice by Leal, Marcos A.S., Dias, Ananda T., Porto, Marcella L., Brun, Bruna F., Gava, Agata L., Meyrelles, Silvana S., Gil-Longo, José, Campos-Toimil, Manuel, Pereira, Thiago M.C., Vasquez, Elisardo C 

“…Background/Aims: The atherosclerotic apolipoprotein E-deficient (apoE -/- ) mouse exhibits impaired vasodilation and enhanced vasoconstriction responsiveness…”
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Beneficial Morphofunctional Changes Promoted by Sildenafil in Resistance Vessels in the Angiotensin II-Induced Hypertension Model by Dias, Ananda T, Leal, Marcos A S, Zanardo, Tadeu C, Alves, Gisele M, Porto, Marcella L, Nogueira, Breno V, Gava, Agata L, Campagnaro, Bianca P, Pereira, Thiago M C, Meyrelles, Silvana S, Campos-Toimil, Manuel, Vasquez, Elisardo C

“…By acting on multiple targets and promoting diverse actions, angiotensin II (Ang II) plays a pivotal role in vascular function. Recent studies suggested that…”
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Mechanisms of enhanced vasoconstriction in the mouse model of atherosclerosis: the beneficial effects of sildenafil by Leal, Marcos A, Balarini, Camille M, Dias, Ananda T, Porto, Marcella L, Gava, Agata L, Pereira, Thiago M C, Meyrelles, Silvana S, Vasquez, Elisardo C

“…Sildenafil ameliorates aortic relaxations in apolipoprotein E knockout (apoE) mice. Now, we tested the hypothesis that endothelial dysfunction (ED) in this…”
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Sildenafil Improves Vascular Endothelial Structure and Function in Renovascular Hypertension by Fahning, Bernah M, Dias, Ananda T, Oliveira, Jairo P, Gava, Agata L, Porto, Marcella L, Gomes, Isabele B S, Nogueira, Breno V, Campagnaro, Bianca P, Pereira, Thiago M C, Vasquez, Elisardo C, Balarini, Camille M, Meyrelles, Silvana S

“…In translational medicine, the discovery of new drugs or new potential uses for currently available drugs is crucial for treating the resistant hypertension…”
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Increased Blood Pressure Variability Prior to Chronic Kidney Disease Exacerbates Renal Dysfunction in Rats by Freitas, Frederico F C T, Araujo, Gilberto, Porto, Marcella L, Freitas, Flavia P S, Graceli, Jones B, Balarini, Camille M, Vasquez, Elisardo C, Meyrelles, Silvana S, Gava, Agata L

“…Increased blood pressure variability (BPV), which can be experimentally induced by sinoaortic denervation (SAD), has emerged as a new marker of the prognosis…”
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Hypercholesterolemia promotes early renal dysfunction in apolipoprotein E-deficient mice by Balarini, Camille M, Oliveira, Mariana Zt, Pereira, Thiago Mc, Silva, Nyam F, Vasquez, Elisardo C, Meyrelles, Silvana S, Gava, Agata L

“…Aging and dyslipidemia are processes which can lead to deleterious consequences to renal function. Therefore, the aim of this study was to determine the…”
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Cardiac-Autonomic Imbalance and Baroreflex Dysfunction in the Renovascular Angiotensin-Dependent Hypertensive Mouse by Campagnaro, Bianca P., Gava, Agata L., Meyrelles, Silvana S., Vasquez, Elisardo C.

“…Mouse models provide powerful tools for studying the mechanisms underlying the dysfunction of the autonomic reflex control of cardiovascular function and those…”
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Endothelial dysfunction of resistance vessels in female apolipoprotein E-deficient mice by Cola, Maine S, Gava, Agata L, Meyrelles, Silvana S, Vasquez, Elisardo C

“…The effects of hypercholesterolemia on vasomotricity in apolipoprotein E-deficient (ApoE) mice, a murine model of spontaneous atherosclerosis, are still…”
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Tributyltin chloride leads to adiposity and impairs metabolic functions in the rat liver and pancreas by Bertuloso, Bruno D., Podratz, Priscila L., Merlo, Eduardo, de Araújo, Julia F.P., Lima, Leandro C.F., de Miguel, Emilio C., de Souza, Leticia N., Gava, Agata L., de Oliveira, Miriane, Miranda-Alves, Leandro, Carneiro, Maria T.W.D., Nogueira, Celia R., Graceli, Jones B.

“…Diagram of the tissue–tissue cross-talk in tributyltin chloride (TBT) and metabolic homeostasis. TBT derived from exogenous sources stimulates (green line) or…”
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Chronic administration of the probiotic kefir improves the endothelial function in spontaneously hypertensive rats by Friques, Andreia G F, Arpini, Clarisse M, Kalil, Ieda C, Gava, Agata L, Leal, Marcos A, Porto, Marcella L, Nogueira, Breno V, Dias, Ananda T, Andrade, Tadeu U, Pereira, Thiago Melo C, Meyrelles, Silvana S, Campagnaro, Bianca P, Vasquez, Elisardo C

“…The beverage obtained by fermentation of milk with kefir grains, a complex matrix containing acid bacteria and yeasts, has been shown to have beneficial…”
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Reactive oxygen species contribute to dysfunction of bone marrow hematopoietic stem cells in aged C57BL/6 J mice by Porto, Marcella L, Rodrigues, Bianca P, Menezes, Thiago N, Ceschim, Sara L, Casarini, Dulce E, Gava, Agata L, Pereira, Thiago Melo C, Vasquez, Elisardo C, Campagnaro, Bianca P, Meyrelles, Silvana S

“…Stem cells of intensely regenerative tissues are susceptible to cellular damage. Although the response to this process in hematopoietic stem cells (HSCs) is…”
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Eugenia uniflora (pitanga) leaf extract prevents the progression of experimental acute kidney injury by Meira, Eduardo F., Oliveira, Nayara D., Mariani, Noemia P., Porto, Marcella L., Severi, Juliana A., Siman, Fabiana D.M., Meyrelles, Silvana S., Vasquez, Elisardo C., Gava, Agata L.

“…[Display omitted] •Preserved renal function and hemodynamics.•Reduced reactive oxygen species formation and apoptosis within the kidney.•Increased antioxidant…”
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Effects of Kefir on the Cardiac Autonomic Tones and Baroreflex Sensitivity in Spontaneously Hypertensive Rats by Klippel, Brunella F, Duemke, Licia B, Leal, Marcos A, Friques, Andreia G F, Dantas, Eduardo M, Dalvi, Rodolfo F, Gava, Agata L, Pereira, Thiago M C, Andrade, Tadeu U, Meyrelles, Silvana S, Campagnaro, Bianca P, Vasquez, Elisardo C

“…It has been previously shown that the probiotic kefir (a symbiotic matrix containing acid bacteria and yeasts) attenuated the hypertension and the endothelial…”
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Tributyltin chloride induces renal dysfunction by inflammation and oxidative stress in female rats by Coutinho, João V.S., Freitas-Lima, Leandro C., Freitas, Frederico F.C.T., Freitas, Flávia P.S., Podratz, Priscila L., Magnago, Rafaella P.L., Porto, Marcella L., Meyrelles, Silvana S., Vasquez, Elisardo C., Brandão, Poliane A.A., Carneiro, Maria T.W.D., Paiva-Melo, Francisca D., Miranda-Alves, Leandro, Silva, Ian V., Gava, Agata L., Graceli, Jones B.

“…[Display omitted] •TBT reduced GFR and increased proteinuria levels in female rats.•TBT increased renal mensagial expansion and collagen deposition.•TBT…”
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Sildenafil ameliorates oxidative stress and DNA damage in the stenotic kidneys in mice with renovascular hypertension by Dias, Ananda T, Rodrigues, Bianca P, Porto, Marcella L, Gava, Agata L, Balarini, Camille M, Freitas, Flavia P S, Palomino, Zaira, Casarini, Dulce E, Campagnaro, Bianca P, Pereira, Thiago M C, Meyrelles, Silvana S, Vasquez, Elisardo C

“…Oxidative stress and DNA damage have been implicated in the pathogenesis of renovascular hypertension induced by renal artery stenosis in the two-kidney,…”
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The protective effects of oral low-dose quercetin on diabetic nephropathy in hypercholesterolemic mice by Gomes, Isabele B S, Porto, Marcella L, Santos, Maria C L F S, Campagnaro, Bianca P, Gava, Agata L, Meyrelles, Silvana S, Pereira, Thiago M C, Vasquez, Elisardo C

“…Diabetic nephropathy (DN) is one of the most important causes of chronic renal disease, and the incidence of DN is increasing worldwide. Considering our…”
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