Search Results - "Gautier, Emilie Fleur"

Proteomic analysis of neutrophils from patients with COVID‐19 by Romana, Marc, Leduc, Marjorie, Hermand, Patricia, Bruce, Johanna, Gautier, Emilie‐Fleur, Martino, Frédéric, Garnier, Yohann, Baccini, Véronique, Le Van Kim, Caroline

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Comprehensive Proteomic Analysis of Human Erythropoiesis by Gautier, Emilie-Fleur, Ducamp, Sarah, Leduc, Marjorie, Salnot, Virginie, Guillonneau, François, Dussiot, Michael, Hale, John, Giarratana, Marie-Catherine, Raimbault, Anna, Douay, Luc, Lacombe, Catherine, Mohandas, Narla, Verdier, Frédérique, Zermati, Yael, Mayeux, Patrick

“…Mass spectrometry-based proteomics now enables the absolute quantification of thousands of proteins in individual cell types. We used this technology to…”
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Phenotypic and proteomic characterization of the human erythroid progenitor continuum reveal dynamic changes in cell cycle and in metabolic pathways by Papoin, Julien, Yan, Hongxia, Leduc, Marjorie, Le Gall, Morgane, Narla, Anupama, Palis, James, Steiner, Laurie A., Gallagher, Patrick G., Hillyer, Christopher D., Gautier, Emilie‐Fleur, Mohandas, Narla, Blanc, Lionel

“…Human erythropoiesis is a complex process leading to the production of 2.5 million red blood cells per second. Following commitment of hematopoietic stem cells…”
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p53 activation during ribosome biogenesis regulates normal erythroid differentiation by Le Goff, Salomé, Boussaid, Ismael, Floquet, Celia, Raimbault, Anna, Hatin, Isabelle, Andrieu-Soler, Charlotte, Salma, Mohammad, Leduc, Marjorie, Gautier, Emilie-Fleur, Guyot, Boris, d'Allard, Diane, Montel-Lehry, Nathalie, Ducamp, Sarah, Houvert, Amandine, Guillonneau, François, Giraudier, Stéphane, Cramer-Bordé, Elisabeth, Morlé, François, Diaz, Jean-Jacques, Hermine, Olivier, Taylor, Naomi, Kinet, Sandrina, Verdier, Frédérique, Padua, Rose-Ann, Mohandas, Narla, Gleizes, Pierre-Emmanuel, Soler, Eric, Mayeux, Patrick, Fontenay, Michaela

“…The role of ribosome biogenesis in erythroid development is supported by the recognition of erythroid defects in ribosomopathies in both Diamond-Blackfan…”
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The proteome of neutrophils in sickle cell disease reveals an unexpected activation of interferon alpha signaling pathway by Hermand, Patricia, Azouzi, Slim, Gautier, Emilie-Fleur, Guillonneau, François, Bondet, Vincent, Duffy, Darragh, Dechavanne, Sebastien, Tharaux, Pierre-Louis, Mayeux, Patrick, Le Van Kim, Caroline, Koehl, Berengere

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Synergistic effect of sildenafil combined with controlled hypothermia to alleviate microglial activation after neonatal hypoxia-ischemia in rats by Julien, Pansiot, Zinni, Manuela, Bonnel, Natacha, El Kamouh, Marina, Odorcyk, Felipe, Peters, Lea, Gautier, Emilie-Fleur, Leduc, Marjorie, Broussard, Cédric, Baud, Olivier

“…The only validated treatment to prevent brain damage associated with hypoxia-ischemia (HI) encephalopathy of the newborn is controlled hypothermia with limited…”
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Integrated analyses of translatome and proteome identify the rules of translation selectivity in RPS14-deficient cells by Boussaid, Ismael, Le Goff, Salomé, Floquet, Célia, Gautier, Emilie-Fleur, Raimbault, Anna, Viailly, Pierre-Julien, Al Dulaimi, Dina, Burroni, Barbara, Dusanter-Fourt, Isabelle, Hatin, Isabelle, Mayeux, Patrick, Cosson, Bertrand, Fontenay, Michaela

“…In ribosomopathies, the Diamond-Blackfan anemia (DBA) or 5q- syndrome, ribosomal protein (RP) genes are affected by mutation or deletion, resulting in bone…”
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XPO1 regulates erythroid differentiation and is a new target for the treatment of β-thalassemia by Guillem, Flavia, Dussiot, Michaël, Colin, Elia, Suriyun, Thunwarat, Arlet, Jean Benoit, Goudin, Nicolas, Marcion, Guillaume, Seigneuric, Renaud, Causse, Sebastien, Gonin, Patrick, Gastou, Marc, Deloger, Marc, Rossignol, Julien, Lamarque, Mathilde, Choucair, Zakia Belaid, Gautier, Emilie Fleur, Ducamp, Sarah, Vandekerckhove, Julie, Moura, Ivan C, Maciel, Thiago Trovati, Garrido, Carmen, An, Xiuli, Mayeux, Patrick, Mohandas, Narla, Courtois, Geneviève, Hermine, Olivier

“…β-thalassemia major (β-TM) is an inherited hemoglobinopathy caused by a quantitative defect in the synthesis of β-globin chains of hemoglobin, leading to the…”
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Infected erythrocytes and plasma proteomics reveal a specific protein signature of severe malaria by Fraering, Jeremy, Salnot, Virginie, Gautier, Emilie-Fleur, Ezinmegnon, Sem, Argy, Nicolas, Peoc’h, Katell, Manceau, Hana, Alao, Jules, Guillonneau, François, Migot-Nabias, Florence, Bertin, Gwladys I, Kamaliddin, Claire

“…Cerebral malaria (CM), the most lethal complication of Plasmodium falciparum severe malaria (SM), remains fatal for 15–25% of affected children despite the…”
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The epigenetic regulator RINF (CXXC5) maintains SMAD7 expression in human immature erythroid cells and sustains red blood cell expansion by Astori, Audrey, Matherat, Gabriel, Munoz, Isabelle, Gautier, Emilie-Fleur, Surdez, Didier, Zermati, Yaël, Verdier, Frédérique, Zaidi, Sakina, Feuillet, Vincent, Kadi, Amir, Lauret, Evelyne, Delattre, Olivier, Lefèvre, Carine, Fontenay, Michaela, Ségal-Bendirdjian, Evelyne, Dusanter-Fourt, Isabelle, Bouscary, Didier, Hermine, Olivier, Mayeux, Patrick, Pendino, Frédéric

“…The gene CXXC5, encoding a retinoid-inducible nuclear factor (RINF), is located within a region at 5q31.2 commonly deleted in myelodysplastic syndrome and…”
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Multiparametric characterization of red blood cell physiology after hypotonic dialysis based drug encapsulation process by Robert, Mélanie, Laperrousaz, Bastien, Piedrahita, Diana, Gautier, Emilie-Fleur, Nemkov, Travis, Dupuy, Florian, Nader, Elie, Salnot, Virginie, Mayeux, Patrick, D'Alessandro, Angelo, Lavazec, Catherine, Joly, Philippe, Scheer, Alexander, Connes, Philippe, Cibiel, Agnès

“…Red blood cells (RBCs) can act as carriers for therapeutic agents and can substantially improve the safety, pharmacokinetics, and pharmacodynamics of many…”
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Comprehensive proteomic analysis of murine terminal erythroid differentiation by Gautier, Emilie-Fleur, Leduc, Marjorie, Ladli, Meriem, Schulz, Vincent P., Lefèvre, Carine, Boussaid, Ismael, Fontenay, Michaela, Lacombe, Catherine, Verdier, Frédérique, Guillonneau, François, Hillyer, Christopher D., Mohandas, Narla, Gallagher, Patrick G., Mayeux, Patrick

“…Murine-based cellular models have provided and continue to provide many useful insights into the fundamental mechanisms of erythropoiesis, as well as insights…”
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S163: POLYSOME INTERACTOME IN RPS14‐DEFICIENT CELLS REVEALS THE INVOLVEMENT OF THE MRNA DECAY MACHINERY IN TRANSLATION SELECTIVITY by Tuerdi, Zubaidan, Levavasseur, Françoise, Falceto‐Font, Laura, Kinyua, Malaïka, Gautier, Emilie‐Fleur, Fourt, Isabelle Dusanter, Fontenay, Michaela, Lauret, Evelyne, Boussaid, Ismael

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Absolute proteome quantification of highly purified populations of circulating reticulocytes and mature erythrocytes by Gautier, Emilie-Fleur, Leduc, Marjorie, Cochet, Sylvie, Bailly, Karine, Lacombe, Catherine, Mohandas, Narla, Guillonneau, François, El Nemer, Wassim, Mayeux, Patrick

“…Reticulocytes produced in the bone marrow undergo maturation in the bloodstream to give rise to erythrocytes. Although the proteome of circulating red cells…”
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Adenosine signaling inhibits erythropoiesis and promotes myeloid differentiation by Mikdar, Mahmoud, Serra, Marion, Colin, Elia, Duval, Romain, Gauthier, Emilie-Fleur, Lamarre, Yann, Colin, Yves, Le Van Kim, Caroline, Peyrard, Thierry, Koehl, Bérengère, Azouzi, Slim

“…Intracellular uptake of adenosine is essential for optimal erythroid commitment and differentiation of hematopoietic progenitor cells. The role of adenosine…”
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Role of Caspase-10-P13tBID axis in erythropoiesis regulation by Lamarque, Mathilde, Gautier, Emilie-Fleur, Rodrigues, François, Guillem, Flavia, Bayard, Elisa, Broussard, Cédric, Maciel Trovati, Thiago, Arlet, Jean-Benoît, Mayeux, Patrick, Hermine, Olivier, Courtois, Geneviève

“…Red blood cell production is negatively controlled by the rate of apoptosis at the stage of CFU-E/pro-erythroblast differentiation, depending on the balance…”
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Lack of the multidrug transporter MRP4/ABCC4 defines the PEL-negative blood group and impairs platelet aggregation by Azouzi, Slim, Mikdar, Mahmoud, Hermand, Patricia, Gautier, Emilie-Fleur, Salnot, Virginie, Willemetz, Alexandra, Nicolas, Gaël, Vrignaud, Cédric, Raneri, Alexandre, Mayeux, Patrick, Bole‐Feysot, Christine, Nitschké, Patrick, Cartron, Jean-Pierre, Colin, Yves, Hermine, Olivier, Jedlitschky, Gabriele, Cloutier, Marc, Constanzo-Yanez, Jessica, Ethier, Carole, Robitaille, Nancy, St-Louis, Maryse, Le Van Kim, Caroline, Peyrard, Thierry

“…The rare PEL-negative phenotype is one of the last blood groups with an unknown genetic basis. By combining whole-exome sequencing and comparative global…”
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Red blood cell proteomics reveal remnant protein biosynthesis and folding pathways in PIEZO1-related hereditary xerocytosis by Caulier, Alexis, Jankovsky, Nicolas, Gautier, Emilie Fleur, El Nemer, Wassim, Guitton, Corinne, Ouled-Haddou, Hakim, Guillonneau, François, Mayeux, Patrick, Salnot, Virginie, Bruce, Johanna, Picard, Véronique, Garçon, Loïc

“…Hereditary xerocytosis is a dominant red cell membrane disorder characterized by an increased leak of potassium from the inside to outside the red blood cell…”
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Altered Ca2+ Homeostasis in Red Blood Cells of Polycythemia Vera Patients Following Disturbed Organelle Sorting during Terminal Erythropoiesis by Buks, Ralfs, Dagher, Tracy, Rotordam, Maria, Monedero Alonso, David, Cochet, Sylvie, Gautier, Emilie-Fleur, Chafey, Philippe, Cassinat, Bruno, Kiladjian, Jean-Jacques, Becker, Nadine, Plo, Isabelle, Egée, Stéphane, El Nemer, Wassim

“…Over 95% of Polycythemia Vera (PV) patients carry the V617F mutation in the tyrosine kinase Janus kinase 2 (JAK2), resulting in uncontrolled erythroid…”
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Upregulation of the CDC25A phosphatase down-stream of the NPM/ALK oncogene participates to anaplastic large cell lymphoma enhanced proliferation by Fernandez-Vidal, Anne, Mazars, Anne, Gautier, Emilie-Fleur, Prévost, Grégoire, Payrastre, Bernard, Manenti, Stéphane

“…Here, we demonstrate that the expression of the dual specificity phosphatase CDC25A, a key regulator of cell cycle progression, is deregulated in Ba/F3 cells…”
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