Search Results - "Gauthier, Theresa W"
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Hyperoxia induces alveolar epithelial-to-mesenchymal cell transition
Published in American journal of physiology. Lung cellular and molecular physiology (15-02-2014)“…Myofibroblast accumulation is a pathological feature of lung diseases requiring oxygen therapy. One possible source for myofibroblasts is through the…”
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Liposomal Glutathione Augments Immune Defenses against Respiratory Syncytial Virus in Neonatal Mice Exposed in Utero to Ethanol
Published in Antioxidants (01-01-2024)“…We previously reported that maternal alcohol use increased the risk of sepsis in premature and term newborns. In the neonatal mouse, fetal ethanol (ETOH)…”
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Placental Fatty Acid ethyl esters are elevated with maternal alcohol use in pregnancies complicated by prematurity
Published in PloS one (15-05-2015)“…The accumulation of fatty acid ethyl esters (FAEEs) in meconium of term newborns has been described as one potential biomarker of maternal alcohol use during…”
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Maternal Alcohol Use During Pregnancy and Associated Morbidities in Very Low Birth Weight Newborns
Published in The American journal of the medical sciences (01-10-2016)“…Abstract Background We hypothesized that maternal alcohol use occurs in pregnancies that end prematurely and that in utero alcohol exposure is associated with…”
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In utero nicotine exposure promotes M2 activation in neonatal mouse alveolar macrophages
Published in Pediatric research (01-08-2012)“…Background: Maternal smoking in utero has been associated with adverse health outcomes including lower respiratory tract infections in infants and children,…”
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Correction: Placental Fatty Acid Ethyl Esters Are Elevated with Maternal Alcohol Use in Pregnancies Complicated by Prematurity
Published in PloS one (19-08-2015)Get full text
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Maternal Alcohol Abuse and Neonatal Infection
Published in Alcoholism, clinical and experimental research (01-06-2005)“…Background: Since chronic alcohol use suppresses the adult immune system, we tested the hypothesis that maternal alcohol ingestion increases the risk of…”
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Comparison of Glutathione, Cysteine, and Their Redox Potentials in the Plasma of Critically Ill and Healthy Children
Published in Frontiers in pediatrics (26-05-2015)“…Oxidative stress is known to play a role in critical illness due to an imbalance in reactive oxygen species and reactive nitrogen species, and the body's…”
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TGF-β1 Suppresses the Type I IFN Response and Induces Mitochondrial Dysfunction in Alveolar Macrophages
Published in The Journal of immunology (1950) (15-03-2018)“…TGF-β1 is a pleiotropic cytokine with an established role in fibrosis; however, the immunosuppressive effects of TGF-β1 are less characterized. Elevated levels…”
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In utero alcohol effects on foetal, neonatal and childhood lung disease
Published in Paediatric respiratory reviews (01-01-2017)“…Summary Maternal alcohol use during pregnancy exposes both premature and term newborns to the toxicity of alcohol and its metabolites. Foetal alcohol exposure…”
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Nitric Oxide Protects Against Leukocyte-Endothelium Interactions in the Early Stages of Hypercholesterolemia
Published in Arteriosclerosis, thrombosis, and vascular biology (01-10-1995)“…We studied the effects of CAS1609, a nitric oxide donor, on leukocyte-endothelial interactions during the early stages of hypercholesterolemia in rat…”
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Role of zinc insufficiency in fetal alveolar macrophage dysfunction and RSV exacerbation associated with fetal ethanol exposure
Published in Alcohol (Fayetteville, N.Y.) (01-11-2019)“…We previously reported that maternal alcohol use significantly increases the risk of sepsis in premature and term newborns. In the mouse, fetal ethanol…”
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Ethyl linolenate is elevated in meconium of very-low-birth-weight neonates exposed to alcohol in utero
Published in Pediatric research (01-03-2017)“…Background: The health implications of in utero alcohol exposure have been difficult to study in very-low-birth-weight newborns (VLBW) because of an inability…”
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Fatty Acid Ethyl Esters Disrupt Neonatal Alveolar Macrophage Mitochondria and Derange Cellular Functioning
Published in Alcoholism, clinical and experimental research (01-03-2015)“…Background Chronic alcohol exposure alters the function of alveolar macrophages (AM), impairing immune defenses in both adult and neonatal lungs. Fatty acid…”
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Glutathione availability modulates alveolar macrophage function in the chronic ethanol-fed rat
Published in American journal of physiology. Lung cellular and molecular physiology (01-04-2007)“…We have previously demonstrated that chronic alcohol exposure decreases glutathione in the alveolar space. Although alcohol use is associated with decreased…”
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Impaired Terminal Differentiation of Pulmonary Macrophages in a Guinea Pig Model of Chronic Ethanol Ingestion
Published in Alcoholism, clinical and experimental research (01-10-2009)“…Background: Alcoholic patients have an increased risk of respiratory infections, which is partially due to an impaired immune response of alveolar…”
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Delayed neonatal lung macrophage differentiation in a mouse model of in utero ethanol exposure
Published in American journal of physiology. Lung cellular and molecular physiology (01-07-2010)“…We have previously demonstrated that fetal ethanol exposure deranges the function and viability of the neonatal alveolar macrophage. Although altered…”
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Prenatal Alcohol Exposure and the Developing Immune System
Published in Alcohol research (22-06-2015)“…Evidence from research in humans and animals suggest that ingesting alcohol during pregnancy can disrupt the fetal immune system and result in an increased…”
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Zinc insufficiency mediates ethanol-induced alveolar macrophage dysfunction in the pregnant female mouse
Published in Alcohol and alcoholism (Oxford) (01-01-2015)“…(a) Establish the minimum number of weeks of chronic ethanol ingestion needed to perturb zinc homeostasis, (b) Examine intracellular zinc status in the…”
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