Search Results - "Gaut, J. P."

Differentiation of human bone marrow mesenchymal stem cells on decellularized extracellular matrix materials by Hoganson, D. M., Meppelink, A. M., Hinkel, C. J., Goldman, S. M., Liu, X.-H., Nunley, R. M., Gaut, J. P., Vacanti, J. P.

“…Mesenchymal bone marrow stromal cells may be a source of cells to preseed decellularized biologic mesh materials for improved cellularization and promote a…”
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Banff Histopathological Consensus Criteria for Preimplantation Kidney Biopsies by Liapis, H., Gaut, J. P., Klein, C., Bagnasco, S., Kraus, E., Farris, A. B., Honsova, E., Perkowska‐Ptasinska, A., David, D., Goldberg, J., Smith, M., Mengel, M., Haas, M., Seshan, S., Pegas, K. L., Horwedel, T., Paliwa, Y., Gao, X., Landsittel, D., Randhawa, P.

“…The Banff working group on preimplantation biopsy was established to develop consensus criteria (best practice guidelines) for the interpretation of…”
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Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions by Hazen, S L, Gaut, J P, Crowley, J R, Hsu, F F, Heinecke, J W

“…Reactive aldehydes might have a pivotal role in the pathogenesis of atherosclerosis by covalently modifying low-density lipoprotein (LDL). However, the…”
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Neutrophils Employ the Myeloperoxidase System to Generate Antimicrobial Brominating and Chlorinating Oxidants during Sepsis by Gaut, Joseph P., Yeh, George C., Tran, Hung Duy, Byun, Jaeman, Henderson, Jeffrey P., Richter, Grace M., Brennan, Marie-Luise, Lusis, Aldons J., Belaaouaj, Abderrazzaq, Hotchkiss, Richard S., Heinecke, Jay W.

“…The myeloperoxidase system of neutrophils uses hydrogen peroxide and chloride to generate hypochlorous acid, a potent bactericidal oxidant in vitro. In a mouse…”
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Mechanisms for Oxidizing Low-Density Lipoprotein: Insights from Patterns of Oxidation Products in the Artery Wall and from Mouse Models of Atherosclerosis by Gaut, Joseph P, Heinecke, Jay W

“…The oxidation hypothesis proposes that oxidative modification of low density lipoprotein (LDL) plays a critical role in atherogenesis. This review critically…”
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Electron Paramagnetic Resonance Detection of Free Tyrosyl Radical Generated by Myeloperoxidase, Lactoperoxidase, and Horseradish Peroxidase by McCormick, Michael L., Gaut, Joseph P., Lin, Tien-Sung, Britigan, Bradley E., Buettner, Garry R., Heinecke, Jay W.

“…Phagocytes secrete the heme protein myeloperoxidase, which is present and active in human atherosclerotic tissue. These cells also generate hydrogen peroxide…”
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Modification of proteins and lipids by myeloperoxidase by Hazen, S L, Hsu, F F, Gaut, J P, Crowley, J R, Heinecke, J W

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p-Hydroxyphenylacetaldehyde, the Major Product of l-Tyrosine Oxidation by the Myeloperoxidase-H2O2-Chloride System of Phagocytes, Covalently Modifies ε-Amino Groups of Protein Lysine Residues by Hazen, Stanley L., Gaut, Joseph P., Hsu, Fong F., Crowley, Jan R., d'Avignon, Andre, Heinecke, Jay W.

“…Activated human phagocytes employ the myeloperoxidase-H2O2-Cl−system to convert l-tyrosine top-hydroxyphenylacetaldehyde (pHA). We have explored the…”
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Differentiation of human bone marrow mesenchymal stem cells on decellularized extracellular matrix materials by Hoganson, D. M., Meppelink, A. M., Hinkel, C. J., Goldman, S. M., Liu, X.-H., Nunley, R. M., Gaut, J. P., Vacanti, J. P.

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Myeloperoxidase Plays Critical Roles in Killing Klebsiella pneumoniae and Inactivating Neutrophil Elastase: Effects on Host Defense by Hirche, Tim O, Gaut, Joseph P, Heinecke, Jay W, Belaaouaj, Azzaq

“…Activated neutrophils use myeloperoxidase (MPO) to generate an array of potent toxic oxidants. In the current studies we used genetically altered mice…”
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Artifact-Free Quantification of Free 3-Chlorotyrosine, 3-Bromotyrosine, and 3-Nitrotyrosine in Human Plasma by Electron Capture–Negative Chemical Ionization Gas Chromatography Mass Spectrometry and Liquid Chromatography–Electrospray Ionization Tandem Mass Spectrometry by Gaut, Joseph P., Byun, Jaeman, Tran, Hung D., Heinecke, Jay W.

“…Halogenation and nitration of biomolecules have been proposed as key mechanisms of host defense against bacteria, fungi, and viruses. Reactive oxidants also…”
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p-Hydroxyphenylacetaldehyde, the major product of L-tyrosine oxidation by the myeloperoxidase-H sub(2)O sub(2)-chloride system of phagocytes, covalently modifies epsilon -amino groups of protein lysine residues by Hazen, S L, Gaut, J P, Hsu, Fong F, Crowley, J R, D'Avignon, A, Heinecke, J W

“…Activated human phagocytes employ the myeloperoxidase-H sub(2)O sub(2)-Cl super(-) system to convert L-tyrosine to p-hydroxyphenylacetaldehyde (pHA). We have…”
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Artifact-Free Quantification of Free 3-Chlorotyrosine, 3-Bromotyrosine, and 3-Nitrotyrosine in Human Plasma by Electron Capture–Negative Chemical Ionization Gas Chromatography Mass Spectrometry and Liquid Chromatography–Electrospray Ionization Tandem Mass Spectrometry by Gaut, Joseph P., Byun, Jaeman, Tran, Hung D., Heinecke, Jay W.

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