Search Results - "Gause, Barry L."

Vaccination With Patient-Specific Tumor-Derived Antigen in First Remission Improves Disease-Free Survival in Follicular Lymphoma by SCHUSTER, Stephen J, NEELAPU, Sattva S, MCGAUGHEY, Dean S, JAFFE, Elaine S, CHONG, Elise A, REYNOLDS, Craig W, BERRY, Donald A, SANTOS, Carlos F, POPA, Mihaela A, MCCORD, Amy M, KWAK, Larry W, GAUSE, Barry L, JANIK, John E, MUGGIA, Franco M, GOCKERMAN, Jon P, WINTER, Jane N, FLOWERS, Christopher R, NIKCEVICH, Daniel A, SOTOMAYOR, Eduardo M

“…Vaccination with hybridoma-derived autologous tumor immunoglobulin (Ig) idiotype (Id) conjugated to keyhole limpet hemocyanin (KLH) and administered with…”
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Human Autologous Tumor-Specific T-Cell Responses Induced by Liposomal Delivery of a Lymphoma Antigen by NEELAPU, Sattva S, BASKAR, Sivasubramanian, POPESCU, Mircea C, KWAK, Larry W, GAUSE, Barry L, KOBRIN, Carol B, WATSON, Thelma M, FRYE, Andrea Robin, PENNINGTON, Robin, HARVEY, Linda, JAFFE, Elaine S, ROBB, Richard J

“…Purpose: The idiotype (Id) of the immunoglobulin on a given B-cell malignancy is a clonal marker that can serve as a tumor-specific antigen. We developed a…”
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Complete molecular remissions induced by patient-specific vaccination plus granulocyte-monocyte colony-stimulating factor against lymphoma by Kwak, Larry W, Bendandi, Maurizio, Gocke, Christopher D, Kobrin, Carol B, Benko, Floyd A, Sternas, Lars A, Pennington, Robin, Watson, Thelma M, Reynolds, Craig W, Gause, Barry L, Duffey, Patricia L, Jaffe, Elaine S, Creekmore, Stephen P, Longo, Dan L

“…Lymphomas express a tumor-specific antigen which can be targeted by cancer vaccination. We evaluated the ability of a new idiotype protein vaccine formulation…”
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A novel proteoliposomal vaccine induces antitumor immunity against follicular lymphoma by Neelapu, Sattva S., Gause, Barry L., Harvey, Linda, Lee, Seung-Tae, Frye, Andrea Robin, Horton, Jessie, Robb, Richard J., Popescu, Mircea C., Kwak, Larry W.

“…Clinical studies suggest that treatment with vaccines comprised of idiotype protein may be associated with improved clinical outcome in follicular lymphoma…”
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The Effects of Treatment with Interleukin-1α on Platelet Recovery after High-Dose Carboplatin by Smith, John W, Longo, Dan L, Alvord, W. Gregory, Janik, John E, Sharfman, William H, Gause, Barry L, Curti, Brendan D, Creekmore, Stephen P, Holmlund, Jon T, Fenton, Robert G, Sznol, Mario, Miller, Langdon L, Shimizu, Masanao, Oppenheim, Joost J, Fiem, Shelby J, Hursey, Jean C, Powers, Gerry C, Urba, Walter J

“…Escalation of the dose of many antineoplastic drugs is limited by granulocytopenia and thrombocytopenia. Although colony-stimulating factors 1 , 2 and the…”
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A prospective randomized phase II trial of GM-CSF priming to prevent topotecan-induced neutropenia in chemotherapy-naive patients with malignant melanoma or renal cell carcinoma by Janik, John E., Miller, Langdon L., Korn, Edward L., Stevens, Diane, Curti, Brendan D., Smith, John W., Sznol, Mario, Conlon, Kevin C., Sharfman, William, Urba, Walter J., Gause, Barry L., Longo, Dan L.

“…We conducted a phase II randomized trial of recombinant granculocyte-macrophage colony-stimulating factor (GM-CSF) administered before topotecan chemotherapy…”
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The potential importance of swainsonine in therapy for cancers and immunology by Olden, K, Breton, P, Grzegorzewski, K, Yasuda, Y, Gause, B L, Oredipe, O A, Newton, S A, White, S L

“…Swainsonine, an indolizidine alkaloid, was initially used in biomedical research as a tool to investigate the biosynthesis and function of asparagine-linked…”
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Interactions between genetic and reproductive factors in breast cancer risk in a population-based sample of African-American families by Chaudru, Valérie, Laing, Amelia, Dunston, Georgia M., Adams-Campbell, Lucile L., Williams, Rosemary, Lynch, John J., Leffall, Lasalle D., Dewitty, Robert L., Gause, Barry L., Bonney, George E., Demenais, Florence

“…Incidence of breast cancer (BC) varies among ethnic groups, with higher rates in white than in African‐American women. Until now, most epidemiological and…”
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Interleukin 1α Increases Serum Leptin Concentrations in Humans by Janik, John E, Curti, Brendan D, Considine, Robert V, Rager, Helen C, Powers, Geraldine C, Alvord, W. Gregory, Smith, John W, Gause, Barry L, Kopp, William C

“…Leptin, the protein product of the ob gene, regulates appetite and body weight in animals. Endotoxin and cytokines, induced by endotoxin, interleukin (IL) 1…”
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Phase III Randomized Trial of Patient-Specific Vaccination for Previously Untreated Patients with Follicular Lymphoma in First Complete Remission: Protocol Summary and Interim Report by Neelapu, Sattva S., Gause, Barry L., Nikcevich, Daniel A., Schuster, Stephen J., Winter, Jane, Gockerman, Jon P., Loughran, Thomas, Takeshita, Ken, Inghirami, Giorgio, McGaughey, Dean, Watson, Thelma M., Snow, Sandra, Kubovic, Paula, Ferraro, Miriam, Jones, Elizabeth, Jaffe, Elaine S., Schwartzentruber, Douglas J., Danforth, David, Sherry, Richard, Kass, Erik, Van Waes, Carter, Reynolds, Craig W., Kwak, Larry W.

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Human Autologous Tumor-Specific T-Cell Responses Induced by Liposome Encapsulated Lymphoma Membrane Proteins by Neelapu, Sattva S., Gause, Barry L., Harvey, Linda, Frye, Andrea R., Horton, Jessie, Robb, Richard J., Popescu, Mircea C., Kwak, Larry W.

“…The unique antigenic determinants (Idiotype [Id]) of the immunoglobulin expressed on a given B cell malignancy can serve as a tumor-specific antigen for active…”
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Phase I trial of anti-CD3-stimulated CD4+ T cells, infusional interleukin-2, and cyclophosphamide in patients with advanced cancer by Curti, B D, Ochoa, A C, Powers, G C, Kopp, W C, Alvord, W G, Janik, J E, Gause, B L, Dunn, B, Kopreski, M S, Fenton, R, Zea, A, Dansky-Ullmann, C, Strobl, S, Harvey, L, Nelson, E, Sznol, M, Longo, D L

“…We performed a phase I trial to determine whether in vivo expansion of activated CD4+ T cells was possible in cancer patients. 111Indium labeling was used to…”
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Combination chemotherapy followed by an immunotoxin (anti-B4-blocked ricin) in patients with indolent lymphoma: results of a phase II study by Longo, D L, Duffey, P L, Gribben, J G, Jaffe, E S, Curti, B D, Gause, B L, Janik, J E, Braman, V M, Esseltine, D, Wilson, W H, Kaufman, D, Wittes, R E, Nadler, L M, Urba, W J

“…The purpose of this article was to evaluate the antitumor effects of a combination chemotherapy program based on ProMACE (prednisone, methotrexate, doxorubicin…”
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Abrogation of the Hematological and Biological Activities of the Interleukin-3/Granulocyte-Macrophage Colony-Stimulating Factor Fusion Protein PIXY321 by Neutralizing Anti-PIXY321 Antibodies in Cancer Patients Receiving High-Dose Carboplatin by Miller, Langdon L., Korn, Edward L., Stevens, Diane S., Janik, John E., Gause, Barry L., Kopp, William C., Holmlund, Jon T., Curti, Brendan D., Sznol, Mario, Smith, John W., Urba, Walter J., Donegan, Sarah E., Watson, Thelma M., Longo, Dan L.

“…This dose-escalation study was performed to evaluate the hematologic activity, biological effects, immunogenicity, and toxicity of PIXY321 (an…”
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Treatment with Tumor Necrosis Factor-α and Granulocyte–Macrophage Colony-Stimulating Factor Increases Epidermal Langerhans' Cell Numbers in Cancer Patients by Janik, John E., Miller, Langdon L., Kopp, William C., Taub, Dennis D., Dawson, Harry, Stevens, Diane, Kostboth, Paige, Curti, Brendan D., Conlon, Kevin C., Dunn, Barbara K., Donegan, Sarah E., Ullrich, Robert, Alvord, W.Gregory, Gause, Barry L., Longo, Dan L.

“…Dendritic cells (DCs) initiate primary and stimulate secondary T-cell responses. We conducted a phase I trial of tumor necrosis factor (TNF-α) and…”
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Development of rheumatoid arthritis after treatment of large granular lymphocyte leukemia with deoxycoformycin by Yoe, Joe, Gause, Barry L., Curti, Brendan D., Longo, Dan L., Bagg, Adam, Kopp, William C., Janik, John E.

“…The association of T‐cell large granular lymphocyte (LGL) leukemia and rheumatoid arthritis is well described and it is now recognized that these patients and…”
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A Phase II Study of Carboplatin, Cisplatin, Interferon-a, and Tamoxifen for Patients with Metastatic Melanoma by Gause, Barry L., Sharfman, William H., Janik, John E., Curti, Brendan D., Steis, Ronald G., Urba, Walter J., Smith, John W., Alvord, W. Gregory, Longo, Dan L.

“…The purpose of this trial was to determine the toxicity and antineoplastic activity of cisplatin, carboplatin, tamoxifen, and interferon-α (IFN-α) in patients…”
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Phase II Trial of Interleukin 1α and Indomethacin in Treatment of Metastatic Melanoma by Janik, John E., Miller, Langdon L., Longo, Dan L., Powers, Geraldine C., Urba, Walter J., Kopp, William C., Gause, Barry L., Curti, Brendan D., Fenton, Robert G., Oppenheim, Joost J., Conlon, Kevin C., Holmlund, Jon T., Sznol, Mario, Sharfman, William H., Steis, Ronald G., Creekmore, Stephen P., Alvord, W. Gregory, Beauchamp, Ann E., Smith, John W.

“…Background: The rising incidence of malignant melanoma and the lack of curative therapies for metastatic disease represent a therapeutic challenge. New agents…”
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A phase II study of carboplatin, cisplatin, interferon-α, and tamoxifen for patients with metastatic melanoma by GAUSE, B. L, SHARFMAN, W. H, JANIK, J. E, CURTI, B. D, RONALD, STEIS, G, URBA, W. J, SMITH, J. W, ALVORD, W. G, ONGO, D. L

“…The purpose of this trial was to determine the toxicity and antineoplastic activity of cisplatin, carboplatin, tamoxifen, and interferon-alpha (IFN-alpha) in…”
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Protective effects of swainsonine on murine survival and bone marrow proliferation during cytotoxic chemotherapy by Oredipe, O A, White, S L, Grzegorzewski, K, Gause, B L, Cha, J K, Miles, V A, Olden, K

“…We have investigated the ability of swainsonine, an indolizidine alkaloid with pleiotropic in vivo effects, to confer protection against the cytotoxic effects…”
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