Search Results - "Gaul, S"

Deletion of fibroblast activation protein provides atheroprotection by Stein, Sokrates, Weber, Julien, Nusser-Stein, Stefanie, Pahla, Jürgen, Zhang, Hui E, Mohammed, Shafeeq A, Oppi, Sara, Gaul, Daniel S, Paneni, Francesco, Tailleux, Anne, Staels, Bart, von Meyenn, Ferdinand, Ruschitzka, Frank, Gorrell, Mark D, Lüscher, Thomas F, Matter, Christian M

“…Abstract Aims Fibroblast activation protein (FAP) is upregulated at sites of tissue remodelling including chronic arthritis, solid tumours, and fibrotic…”
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Deleterious role of endothelial lectin-like oxidized low-density lipoprotein receptor-1 in ischaemia/reperfusion cerebral injury by Akhmedov, Alexander, Bonetti, Nicole R, Reiner, Martin F, Spescha, Remo D, Amstalden, Heidi, Merlini, Mario, Gaul, Daniel S, Diaz-Cañestro, Candela, Briand-Schumacher, Sylvie, Spescha, Rebecca S, Semerano, Aurora, Giacalone, Giacomo, Savarese, Gianluigi, Montecucco, Fabrizio, Kulic, Luka, Nitsch, Roger M, Matter, Christian M, Kullak-Ublick, Gerd A, Sessa, Maria, Lüscher, Thomas F, Beer, Jürg H, Liberale, Luca, Camici, Giovanni G

“…Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is implicated in cardiovascular disease by modulating apoptosis and oxidative stress. We…”
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Ticagrelor, but not clopidogrel, reduces arterial thrombosis via endothelial tissue factor suppression by Reiner, Martin F, Akhmedov, Alexander, Stivala, Simona, Keller, Stephan, Gaul, Daniel S, Bonetti, Nicole R, Savarese, Gianluigi, Glanzmann, Martina, Zhu, Cuicui, Ruf, Wolfram, Yang, Zhihong, Matter, Christian M, Lüscher, Thomas F, Camici, Giovanni G, Beer, Juerg H

“…The P2Y antagonist ticagrelor reduces mortality in patients with acute coronary syndrome (ACS), compared with clopidogrel, and the mechanisms underlying this…”
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Neutrophils in cardiovascular disease by Gaul, Daniel S, Stein, Sokrates, Matter, Christian M

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Effect of direct-fed microbial Bacillus subtilis C-3102 on enteric health in nursery pigs after challenge with porcine epidemic diarrhea virus by Canning, Paisley, Ruston, Chelsea, Madson, Daren, Bates, Jessica, Skoland, Kristin, Davenport, Jessica, Gaul, S, Wang, C, Chen, Q, Zhang, J, Karriker, Locke

“…Objective: To examine the effects of feeding Bacillus subtilis C-3102 at the target inclusion rates of 0 colony forming units (CFU) per g, 500,000 CFU per g,…”
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Endothelial SIRT6 blunts stroke size and neurological deficit by preserving blood–brain barrier integrity: a translational study by Liberale, Luca, Gaul, Daniel S, Akhmedov, Alexander, Bonetti, Nicole R, Nageswaran, Vanasa, Costantino, Sarah, Pahla, Jürgen, Weber, Julien, Fehr, Vera, Vdovenko, Daria, Semerano, Aurora, Giacalone, Giacomo, Kullak-Ublick, Gerd A, Sessa, Maria, Eriksson, Urs, Paneni, Francesco, Ruschitzka, Frank, Montecucco, Fabrizio, Beer, Jürg H, Lüscher, Thomas F, Matter, Christian M, Camici, Giovanni G

“…Abstract Aims Aging is an established risk factor for stroke; genes regulating longevity are implicated in the pathogenesis of ischaemic stroke where to date,…”
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Erysipelothrix rhusiopathiae: genetic characterization of midwest US isolates and live commercial vaccines using pulsed-field gel electrophoresis by Opriessnig, T, Hoffman, LJ, Harris, DL, Gaul, SB, Halbur, PG

“…Department of Veterinary Diagnostic and Production Animal Medicine, Iowa State University, Ames, IA 50011, USA. This is the first report of molecular…”
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Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity by Gaul, Daniel S, Weber, Julien, van Tits, Lambertus J, Sluka, Susanna, Pasterk, Lisa, Reiner, Martin F, Calatayud, Natacha, Lohmann, Christine, Klingenberg, Roland, Pahla, Jürgen, Vdovenko, Daria, Tanner, Felix C, Camici, Giovanni G, Eriksson, Urs, Auwerx, Johan, Mach, François, Windecker, Stephan, Rodondi, Nicolas, Lüscher, Thomas F, Winnik, Stephan, Matter, Christian M

“…Abstract Aims Sirtuin 3 (Sirt3) is a mitochondrial, nicotinamide adenine dinucleotide (NAD+)-dependent deacetylase that reduces oxidative stress by activation…”
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Endothelial SIRT6 deficiency promotes arterial thrombosis in mice by Gaul, Daniel S., Calatayud, Natacha, Pahla, Jürgen, Bonetti, Nicole R., Wang, Yu-Jen, Weber, Julien, Ambrosini, Samuele, Liberale, Luca, Costantino, Sarah, Mohammed, Shafeeq A., Kraler, Simon, Van Tits, Lambertus J., Pasterk, Lisa, Vdovenko, Daria, Akhmedov, Alexander, Ruschitzka, Frank, Paneni, Francesco, Lüscher, Thomas F., Camici, Giovanni G., Matter, Christian M.

“…Arterial thrombosis may be initiated by endothelial inflammation or denudation, activation of blood-borne elements or the coagulation system. Tissue factor…”
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Sirt6 deletion in bone marrow-derived cells increases atherosclerosis – Central role of macrophage scavenger receptor 1 by Arsiwala, Tasneem, Pahla, Jürgen, van Tits, Lambertus J., Bisceglie, Lavinia, Gaul, Daniel S., Costantino, Sarah, Miranda, Melroy X., Nussbaum, Kathrin, Stivala, Simona, Blyszczuk, Przemyslaw, Weber, Julien, Tailleux, Anne, Stein, Sokrates, Paneni, Francesco, Beer, Jürg H., Greter, Melanie, Becher, Burkhard, Mostoslavsky, Raul, Eriksson, Urs, Staels, Bart, Auwerx, Johan, Hottiger, Michael O., Lüscher, Thomas F., Matter, Christian M.

“…Sirtuin 6 (Sirt6) is a NAD+-dependent deacetylase that plays a key role in DNA repair, inflammation and lipid regulation. Sirt6-null mice show severe metabolic…”
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Pyridinone Derivatives: Specific Human Immunodeficiency Virus Type 1 Reverse Transcriptase Inhibitors with Antiviral Activity by Goldman, Mark E., Nunberg, Jack H., O'Brien, Julie A., Quintero, Julio C., Schleif, William A., Freund, Kurt F., Gaul, S. Lee, Saari, Walfred S., Wai, John S., Hoffman, Jacob M., Anderson, Paul S., Hupe, Donald J., Emini, Emilio A., Stern, Andrew M.

“…Derivatives of pyridinones were found to inhibit human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) activity and prevent the spread of…”
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Deletion of Sirt3 does not affect atherosclerosis but accelerates weight gain and impairs rapid metabolic adaptation in LDL receptor knockout mice: implications for cardiovascular risk factor development by Winnik, Stephan, Gaul, Daniel S., Preitner, Frédéric, Lohmann, Christine, Weber, Julien, Miranda, Melroy X., Liu, Yilei, van Tits, Lambertus J., Mateos, José María, Brokopp, Chad E., Auwerx, Johan, Thorens, Bernard, Lüscher, Thomas F., Matter, Christian M.

“…Sirt3 is a mitochondrial NAD + -dependent deacetylase that governs mitochondrial metabolism and reactive oxygen species homeostasis. Sirt3 deficiency has been…”
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Mild endothelial dysfunction in Sirt3 knockout mice fed a high-cholesterol diet: protective role of a novel C/EBP-β-dependent feedback regulation of SOD2 by Winnik, Stephan, Gaul, Daniel S., Siciliani, Giovanni, Lohmann, Christine, Pasterk, Lisa, Calatayud, Natacha, Weber, Julien, Eriksson, Urs, Auwerx, Johan, van Tits, Lambertus J., Lüscher, Thomas F., Matter, Christian M.

“…Sirtuin 3 (Sirt3) is an NAD + -dependent mitochondrial deacetylase associated with superoxide dismutase 2 (SOD2)-mediated protection from oxidative stress. We…”
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Integrated Pest Management of Rhagoletis mendax (Diptera: Tephritidae) in Lowbush Blueberry using Vegetative Field Management by Gaul, S. O, Mcrae, K. B, Estabrooks, E. N

“…Economic control of Rhagoletis mendax was achieved by applying insecticidal sprays to commercial lowbush blueberry vegetative fields, in a biennial production…”
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Compound screening identifies novel inhibitors of monocyte pyroptosis and interleukin 1-beta release by Kogel, A., Baumann, R., Gaul, S., Schaefer, M., Kalwa, H., Laufs, U.

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Identification of low molecular weight GP IIb/IIIa antagonists that bind preferentially to activated platelets by Bednar, R A, Gaul, S L, Hamill, T G, Egbertson, M S, Shafer, J A, Hartman, G D, Gould, R J, Bednar, B

“…A critical function of fibrinogen in hemostasis and thrombosis is to mediate platelet aggregation by binding selectively to an activated form of glycoprotein…”
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Non-Peptide GPIIb/IIIa Inhibitors. 20. Centrally Constrained Thienothiophene α-Sulfonamides Are Potent, Long Acting in Vivo Inhibitors of Platelet Aggregation by Egbertson, Melissa S, Cook, Jacquelynn J, Bednar, Bohumil, Prugh, John D, Bednar, Rodney A, Gaul, Stanley L, Gould, Robert J, Hartman, George D, Homnick, Carl F, Holahan, Marie A, Libby, Laura A, Lynch, Joseph J, Lynch, Robert J, Sitko, Gary R, Stranieri, Maria T, Vassallo, Laura M

“…The synthesis and pharmacology of 4, a potent thienothiophene non-peptide fibrinogen receptor antagonist, are reported. Compound 4 inhibited the aggregation of…”
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A probable case of congenital syphilis from 18th century Vienna by Gaul, Johanna S, Grossschmidt, Karl

“…Archaeological excavation of a historic cemetery in Vienna, Austria, dating to the Josephinian period (CE 1765-1790) yielded a likely case of congenital…”
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The uptake of trimethylamine N-oxide (TMAO) and its influence on endothelial cell identity and inflammation by Rittig, S, Gaal, L, Kokot, K, Gaul, S, Okun, J, Laufs, U, Boeckel, J.-N

“…Abstract Background and purpose Trimethylamine N-oxide (TMAO) is associated with a higher risk of atherosclerotic diseases. However, the underlying molecular…”
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Articular fractures of the proximal interphalangeal joint with missing elements: Repair with partial toe joint osteochondral autografts by Gaul, J.Stuart

“…Five cases of traumatic destruction of a condyle of the proximal interphalangeal joint repaired with a free autogenous graft of a corresponding toe condyle are…”
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