Search Results - "Gaugler, Beatrice"

Old dog, new trick: Trivalent arsenic as an immunomodulatory drug by Ye, Yishan, Gaugler, Béatrice, Mohty, Mohamad, Malard, Florent

“…Trivalent arsenic (As(III)) is recently found to be an immunomodulatory agent. As(III) has therapeutic potential in several autoimmune and inflammatory…”
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Plasmacytoid dendritic cell biology and its role in immune‐mediated diseases by Ye, Yishan, Gaugler, Béatrice, Mohty, Mohamad, Malard, Florent

“…Plasmacytoid dendritic cells (pDCs) are a unique subset of dendritic cells specialised in secreting high levels of type I interferons. pDCs play a crucial role…”
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Increased IL-22- and IL-17A-Producing Mucosal-Associated Invariant T Cells in the Peripheral Blood of Patients With Ankylosing Spondylitis by Toussirot, Éric, Laheurte, Caroline, Gaugler, Béatrice, Gabriel, Damien, Saas, Philippe

“…The IL-23/T helper 17 (Th17) axis plays an important role in joint inflammation in ankylosing spondylitis (AS). Conventional CD4 Th17 cells are a major source…”
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Faecal microbiota transplantation in patients with haematological malignancies undergoing cellular therapies: from translational research to routine clinical practice by Malard, Florent, Gaugler, Béatrice, Mohty, Mohamad

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Biology and clinical relevance of follicular cytotoxic T cells by Lv, Yuqi, Ricard, Laure, Gaugler, Béatrice, Huang, He, Ye, Yishan

“…Follicular cytotoxic T (Tfc) cells are a newly identified subset of CD8 T cells enriched in B cell follicles and their surroundings, which integrate multiple…”
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A bit of sweetness for GVHD prevention by Mohty, Mohamad, Gaugler, Béatrice

“…In this issue of Blood, Parmar et al report on preclinical data suggesting that use of ex vivo fucosylated third-party human regulatory T cells (Tregs) could…”
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Increased regulatory T-cell numbers are associated with farm milk exposure and lower atopic sensitization and asthma in childhood by Lluis, Anna, PhD, Depner, Martin, PhD, Gaugler, Beatrice, PhD, Saas, Philippe, PhD, Casaca, Vera Isabel, MSc, Raedler, Diana, Michel, Sven, MSc, Tost, Jorg, PhD, Liu, Jing, MD, Genuneit, Jon, MD, Pfefferle, Petra, PhD, Roponen, Marjut, PhD, Weber, Juliane, MD, Braun-Fahrländer, Charlotte, MD, Riedler, Josef, MD, Lauener, Roger, MD, Vuitton, Dominique Angèle, PhD, Dalphin, Jean-Charles, MD, PhD, Pekkanen, Juha, MD, von Mutius, Erika, MD, MSc, Schaub, Bianca, MD

“…Background European cross-sectional studies have suggested that prenatal and postnatal farm exposure decreases the risk of allergic diseases in childhood…”
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Serum adipokines, adipose tissue measurements and metabolic parameters in patients with advanced radiographic knee osteoarthritis by Toussirot, Eric, Michel, Fabrice, Béreau, Matthieu, Dehecq, Barbara, Gaugler, Béatrice, Wendling, Daniel, Grandclément, Emilie, Saas, Philippe, Dumoulin, Gilles

“…We conducted the present study to evaluate the serum levels of adipokines (leptin, total and high molecular adiponectin, resistin), a marker of cartilage…”
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Impact of HDAC inhibitors on dendritic cell functions by Frikeche, Jihane, Peric, Zinaida, Brissot, Eolia, Grégoire, Marc, Gaugler, Béatrice, Mohty, Mohamad

“…Histone deacetylase inhibitors are presently used in the routine clinic treatment against cancers. Recent data have established that some of these treatments…”
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Impact of valproic acid on dendritic cells function by Frikeche, Jihane, Simon, Thomas, Brissot, Eolia, Grégoire, Marc, Gaugler, Béatrice, Mohty, Mohamad

“…Abstract Objective Recent data suggested that histone deacetylase (HDAC) inhibitors possessed potent anti-inflammatory and immunomodulatory properties both in…”
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Intravenous apoptotic cell infusion as a cell-based therapy toward improving hematopoietic cell transplantation outcome by Saas, Philippe, Gaugler, Béatrice, Perruche, Sylvain

“…Allogeneic hematopoietic cell transplantation (AHCT) is an efficient therapy for different malignant and nonmalignant hematological diseases. However, the use…”
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Histone deacetylase inhibitor valproic acid affects plasmacytoid dendritic cells phenotype and function by Arbez, Jessy, Lamarthée, Baptiste, Gaugler, Béatrice, Saas, Philippe

“…Abstract Objective Plasmacytoid dendritic cells (PDC) represent a rare subset of dendritic cells specialized in the production of type I IFN in response to…”
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Interleukin-22 in Graft-Versus-Host Disease after Allogeneic Stem Cell Transplantation by Lamarthée, Baptiste, Malard, Florent, Saas, Philippe, Mohty, Mohamad, Gaugler, Béatrice

“…Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a potential curative treatment for hematologic malignancies and non-malignant diseases…”
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Inflammatory cytokines and dendritic cells in acute graft-versus-host disease after allogeneic stem cell transplantation by Mohty, Mohamad, Gaugler, Béatrice

“…Abstract The wider use of allogeneic stem cell transplantation (allo-SCT) is still limited by the immunologic recognition and destruction of host tissues,…”
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Introduction to host microbiome symbiosis in health and disease by Malard, Florent, Dore, Joel, Gaugler, Béatrice, Mohty, Mohamad

“…Humans share a core intestinal microbiome and yet human microbiome differs by genes, species, enterotypes (ecology), and gene count (microbial diversity)…”
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Impact of donor hematopoietic cells mobilized with G-CSF and plerixafor on murine acute graft-versus-host-disease by Arbez, Jessy, Saas, Philippe, Lamarthée, Baptiste, Malard, Florent, Couturier, Mélanie, Mohty, Mohamad, Gaugler, Béatrice

“…Abstract Background aims This study aimed to characterize the immune effectors contained in the grafts from donor mice mobilized by granulocyte…”
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Mechanisms of action of antithymocyte globulin: old dogs with new tricks by Mohty, Mohamad, Gaugler, Béatrice

“…Understanding the mechanisms underlying immunological tolerance is the key to successful transplantation. Recent findings demonstrate that polyclonal…”
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Advances in umbilical cord transplantation: the role of thymoglobulin/ATG in cord blood transplantation by Mohty, Mohamad, MD, Ph.D, Gaugler, Beatrice, Ph.D

“…Umbilical cord blood transplantation (UCBT) is increasingly being used as an alternative to conventional allogeneic stem cell transplantation. However, despite…”
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Prospective phase II study of prophylactic low-dose azacitidine and donor lymphocyte infusions following allogeneic hematopoietic stem cell transplantation for high-risk acute myeloid leukemia and myelodysplastic syndrome by Guillaume, Thierry, Malard, Florent, Magro, Leonardo, Labopin, Myriam, Tabrizi, Reza, Borel, Cécile, Chevallier, Patrice, Vigouroux, Stéphane, Peterlin, Pierre, Garnier, Alice, Rubio, Marie-Thérèse, Huynh, Anne, Milpied, Noël, Moreau, Philippe, Gaugler, Béatrice, Yakoub-Agha, Ibrahim, Mohty, Mohamad

“…Thirty patients, with high-risk acute myeloid leukemia (AML, n  = 20) or myelodysplastic syndrome (MDS, n  = 10), were enrolled in a phase II trial entailing…”
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Weak immunogenicity of SARS-CoV-2 vaccine in patients with hematologic malignancies by Malard, Florent, Gaugler, Béatrice, Gozlan, Joel, Bouquet, Lucie, Fofana, Djeneba, Siblany, Lama, Eshagh, Deborah, Adotevi, Olivier, Laheurte, Caroline, Ricard, Laure, Dulery, Rémy, Stocker, Nicolas, van de Wyngaert, Zoe, Genthon, Alexis, Banet, Anne, Memoli, Mara, Ikhlef, Souhila, Sestilli, Simona, Vekhof, Anne, Brissot, Eolia, Marjanovic, Zora, Chantran, Yannick, Cuervo, Nancy, Ballot, Eric, Morand-Joubert, Laurence, Mohty, Mohamad

“…This study evaluated the safety and immunogenicity of BNT162b2 vaccine in patients with hematological malignancies. Antibodies blocking spike binding to…”
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