Search Results - "Gaudette, G R"

Single cycle to failure in bending of three standard and five locking plates and plate constructs by Blake, C A, Boudrieau, R J, Torrance, B S, Tacvorian, E K, Cabassu, J B, Gaudette, G R, Kowaleski, M P

“…To evaluate the biomechanical properties of standard and locking plates in bending. We hypothesised that titanium (Ti) constructs would have the greatest…”
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Single cycle to failure in torsion of three standard and five locking plate constructs by Cabassu, J B, Kowaleski, M P, Skorinko, J K, Shorinko, J K, Blake, C A, Gaudette, G R, Boudrieau, R J

“…The biomechanical properties of standard plates and recently designed locking plates were compared in torsion. We hypothesized that titanium (Ti) constructs…”
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Ischemic but not pharmacological preconditioning requires protein synthesis by MATSUYAMA, Nanritsu, LEAVENS, John E, MCKINNON, David, GAUDETTE, Glenn R, AKSEHIRLI, Tunc O, KRUKENKAMP, Irvin B

“…Ischemic preconditioning (IPC) and pharmacological preconditioning (PPC) have both been shown to confer cardioprotective effects. However, the role of protein…”
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Nitric oxide–generating β-adrenergic blocker nipradilol preserves postischemic cardiac function by Horimoto, Hitoshi, Saltman, Adam E, Gaudette, Glenn R, Krukenkamp, Irvin B

“…Background. Preconditioning protects the heart from ischemic injury, but some of its effects are reversed by β-adrenergic blockade. We hypothesize that because…”
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Is the preconditioning response conserved in senescent myocardium? by Burns, Paul G., Krukenkamp, Irvin B., Caldarone, Christopher A., Kirvaitis, Romas J., Gaudette, Glenn R., Levitsky, Sidney

“…Senescent myocardium differs from adult myocardium at both functional and cellular levels. To adjudicate the efficacy of ischemic preconditioning as an…”
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Adenosine-enhanced ischemic preconditioning decreases infarct in the regional ischemic sheep heart by Uematsu, Masahisa, Gaudette, Glenn R., Laurikka, Jari O., Levitsky, Sidney, McCully, James D.

“…Background. Recently we have reported a myoprotective protocol, adenosine-enhanced ischemic preconditioning, that extends the protection afforded by ischemic…”
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Myocardial Recovery from Ischemia Is Impaired in CD36-Null Mice and Restored by Myocyte CD36 Expression or Medium-Chain Fatty Acids by Irie, Hiroshi, Krukenkamp, Irvin B., Joep F. F. Brinkmann, Gaudette, Glenn R., Saltman, Adam E., Jou, William, Jan F. C. Glatz, Abumrad, Nada A., Ibrahimi, Azeddine

“…Long-chain fatty acid uptake, which provides a large part of myocardial energy, is impaired in human and murine hearts deficient in the membrane fatty acid…”
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Phorbol-12,13-dibutyrate and pinacidil cardioplegia : Novel forms of myoprotection by KIRVAITIS, R. J, KRUKENKAMP, I. B, GAUDETTE, G. R, MIYATAKE, T, LEVITSKY, S

“…Activation of either protein kinase C or the ATP-sensitive potassium channel has been shown to induce the preconditioning response. To investigate whether…”
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Blood cardioplegia in the senescent heart by Caldarone, Christopher A., Krukenkamp, Irvin B., Burns, Paul G., Gaudette, Glenn R., Schulman, Joshua, Levitsky, Sidney

“…As an increasingly aged population undergoes cardiac surgery, myocardial protective strategies must address the fundamental differences between adult and…”
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Computer aided speckle interferometry: a technique for measuring deformation of the surface of the heart by Gaudette, G R, Todaro, J, Krukenkamp, I B, Chiang, F P

“…An investigation of the inhomogeneous and anisotropic properties of myocardium necessitates a whole field measurement technique with high spatial resolution…”
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Preconditioning with PKC and the ATP-sensitive potassium channels: a codependent relationship by Gaudette, Glenn R, Krukenkamp, Irvin B, Saltman, Adam E, Horimoto, Hitoshi, Levitsky, Sidney

“…Background. Both potassium channel openers and protein kinase C have been shown to independently elicit the myoprotective preconditioning response. However,…”
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Effects of ischemia on epicardial deformation in the passive rabbit heart by Gaudette, Glenn R, Krukenkamp, Irvin B, Azeloglu, Evren U, Saltman, Adam E, Lense, Miriam, Todaro, Joseph, Chiang, Fu-Pen

“…Surgically induced ischemia in the arrested heart can result in changes in the mechanical properties of the myocardium. Regions of ischemia may be…”
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The Role of Nitric Oxide, K+ATP Channels, and cGMP in the Preconditioning Response of the Rabbit by Horimoto, Hitoshi, Gaudette, Glenn R., Saltman, Adam E., Krukenkamp, Irvin B.

“…Background. The role of nitric oxide (NO), K+ATP channels, and cyclic GMP (cGMP) in preconditioning is unknown. Material and methods. Isolated rabbit hearts…”
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Pharmacological preconditioning with the adenosine triphosphate–sensitive potassium channel opener pinacidil by Saltman, Adam E, Krukenkamp, Irvin B, Gaudette, Glenn R, Horimoto, Hitoshi, Levitsky, Sidney

“…Background. Ischemic preconditioning (IPC) decreases infarct size after global or regional ischemia. Potassium channel openers also precondition but are…”
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Amrinone preconditioning in the isolated perfused rabbit heart by Saltman, Adam E, Gaudette, Glenn R, Levitsky, Sidney, Krukenkamp, Irvin B

“…Background. Ischemic preconditioning (IPC) reduces infarct size in experimental preparations. IPC, however, is not without detrimental effects. We studied…”
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Does cardiopulmonary bypass alone elicit myoprotective preconditioning? by Burns, P G, Krukenkamp, I B, Caldarone, C A, Gaudette, G R, Bukhari, E A, Levitsky, S

“…Brief episodes of ischemia can precondition myocardium. Ischemic preconditioning (PC) has been proposed as an adjuvant method of improving myocardial…”
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Development and characterization of a 3D multicell microtissue culture model of airway smooth muscle by West, Adrian R, Zaman, Nishat, Cole, Darren J, Walker, Matthew J, Legant, Wesley R, Boudou, Thomas, Chen, Christopher S, Favreau, John T, Gaudette, Glenn R, Cowley, Elizabeth A, Maksym, Geoffrey N

“…Airway smooth muscle (ASM) cellular and molecular biology is typically studied with single-cell cultures grown on flat 2D substrates. However, cells in vivo…”
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Does aprotinin increase the myocardial damage in the setting of ischemia and preconditioning? by Bukhari, Emad A., Krukenkamp, Irvin B., Burns, Paul G., Gaudette, Glenn R., Schulman, Joshua J., Al-Fagih, Mohammed R., Levitsky, Sidney

“…Aprotinin reduces postoperative bleeding in cardiac operations, but its association with perioperative myocardial infarction remains controversial. Ischemic…”
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Increased myocyte content and mechanical function within a tissue-engineered myocardial patch following implantation by Kelly, Damon J, Rosen, Amy B, Schuldt, Adam J T, Kochupura, Paul V, Doronin, Sergey V, Potapova, Irina A, Azeloglu, Evren U, Badylak, Stephen F, Brink, Peter R, Cohen, Ira S, Gaudette, Glenn R

“…During the past few years, studies involving the implantation of stem cells, chemical factors, and scaffolds have demonstrated the ability to augment the…”
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Ischemia-dependent efficacy of phosphodiesterase inhibition by Caldarone, Christopher A., Krukenkamp, Irvin B., Burns, Paul G., Misare, Bruce D., Gaudette, Glenn R., Levitsky, Sidney

“…To evaluate the inotropic efficacy of phosphodiesterase inhibition in hearts with and without ischemic injury, 27 sheep were evaluated sonomicrometrically…”
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