Search Results - "Gaudet, G"

Cytosolic detection of the bacterial metabolite HBP activates TIFA-dependent innate immunity by Gaudet, Ryan G., Sintsova, Anna, Buckwalter, Carolyn M., Leung, Nelly, Cochrane, Alan, Li, Jianjun, Cox, Andrew D., Moffat, Jason, Gray-Owen, Scott D.

“…Host recognition of pathogen-associated molecular patterns (PAMPs) initiates an innate immune response that is critical for pathogen elimination and engagement…”
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Heptose Sounds the Alarm: Innate Sensing of a Bacterial Sugar Stimulates Immunity by Gaudet, Ryan G, Gray-Owen, Scott D

“…[...]we recently discovered that the second molecule generated in this pathway, heptose-1,7-bisphosphate (HBP), elicits an inflammatory response from mammalian…”
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Antibodies in infectious diseases: polyclonals, monoclonals and niche biotechnology by Berry, Jody D., Gaudet, Ryan G.

“…Antibody preparations have a long history of providing protection from infectious diseases. Although antibodies remain the only natural host-derived defense…”
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Cardiac arrest during deep brain stimulation: A case report by Oberholzer, Julian, Fayolle, Damien, Vandenbulcke, Alberto, Gaudet, John G.

“…Key Clinical Message We present the case of a 54‐year‐old male with severe Parkinson's disease and chronic, non‐reversible pulmonary artery hypertension who…”
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Innate Recognition of Intracellular Bacterial Growth Is Driven by the TIFA-Dependent Cytosolic Surveillance Pathway by Gaudet, Ryan G., Guo, Cynthia X., Molinaro, Raphael, Kottwitz, Haila, Rohde, John R., Dangeard, Anne-Sophie, Arrieumerlou, Cécile, Girardin, Stephen E., Gray-Owen, Scott D.

“…Intestinal epithelial cells (IECs) act as sentinels for incoming pathogens. Cytosol-invasive bacteria, such as Shigella flexneri, trigger a robust…”
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Neisseria gonorrhoeae-derived heptose elicits an innate immune response and drives HIV-1 expression by Malott, Rebecca J., Keller, Bernd O., Gaudet, Ryan G., McCaw, Shannon E., Lai, Christine C. L., Dobson-Belaire, Wendy N., Hobbs, J. Leigh, St. Michael, Frank, Cox, Andrew D., Moraes, Trevor F., Gray-Owen, Scott D.

“…Clinical and epidemiological synergy exists between the globally important sexually transmitted infections, gonorrhea and HIV. Neisseria gonorrhoeae , which…”
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Neurocognitive Performance in Hypertensive Patients after Spine Surgery by YOCUM, Gene T, GAUDET, John G, TEVERBAUGH, Lauren A, QUEST, Donald O, MCCORMICK, Paul C, SANDER CONNOLLY, E, HEYER, Eric J

“…Cognitive dysfunction is fairly common after noncardiac surgery and may be related to intraoperative blood pressure management. The authors present an analysis…”
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TIFA Signaling in Gastric Epithelial Cells Initiates the cag Type 4 Secretion System-Dependent Innate Immune Response to Helicobacter pylori Infection by Gall, Alevtina, Gaudet, Ryan G, Gray-Owen, Scott D, Salama, Nina R

“…is a bacterial pathogen that colonizes the human stomach, causing inflammation which, in some cases, leads to gastric ulcers and cancer. The clinical outcome…”
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European guidelines on peri-operative venous thromboembolism prophylaxis: first update.: Chapter 6: Neurosurgery by Mora, Lidia, Gaudet, John G, Bilotta, Federico, Bruder, Nicolas

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A human apolipoprotein L with detergent-like activity kills intracellular pathogens by Gaudet, Ryan G, Zhu, Shiwei, Halder, Anushka, Kim, Bae-Hoon, Bradfield, Clinton J, Huang, Shuai, Xu, Dijin, Mamiñska, Agnieszka, Nguyen, Thanh Ngoc, Lazarou, Michael, Karatekin, Erdem, Gupta, Kallol, MacMicking, John D

“…Activation of cell-autonomous defense by the immune cytokine interferon-γ (IFN-γ) is critical to the control of life-threatening infections in humans. IFN-γ…”
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Molecular characterization of the cervical and systemic B-cell repertoire: Unique, yet overlapping, immune compartments of an HIV-1 resistant individual by Gaudet, Ryan G., Breden, Felix, Plummer, Frank, Berry, Jody D.

“…The cervical mucosa of women who are highly exposed to HIV-1, yet remain persistently seronegative (HEPS), presents a unique opportunity to study the dynamics…”
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The Enhanced Recovery After Surgery protocol for the perioperative management of pituitary neuroendocrine tumors/pituitary adenomas by Cossu, Giulia, Belouaer, Amani, Kloeckner, Julie, Caliman, Catalina, Agri, Fabio, Daniel, Roy Thomas, Gaudet, John G, Papadakis, Georgios E, Messerer, Mahmoud

“…Enhanced Recovery After Surgery (ERAS) is a multimodal perioperative care pathway that has radically modified the management of patients in multiple surgical…”
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The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling by Abdel-Nour, Mena, Carneiro, Leticia A M, Downey, Jeffrey, Tsalikis, Jessica, Outlioua, Ahmed, Prescott, Dave, Da Costa, Leandro Silva, Hovingh, Elise S, Farahvash, Armin, Gaudet, Ryan G, Molinaro, Raphael, van Dalen, Rob, Lau, Charles C Y, Azimi, Farshad C, Escalante, Nichole K, Trotman-Grant, Aaron, Lee, Jeffrey E, Gray-Owen, Scott D, Divangahi, Maziar, Chen, Jane-Jane, Philpott, Dana J, Arnoult, Damien, Girardin, Stephen E

“…Multiple cytosolic innate sensors form large signalosomes after activation, but this assembly needs to be tightly regulated to avoid accumulation of misfolded…”
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PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection by Xu, Dijin, Jiang, Weiqian, Wu, Lizhen, Gaudet, Ryan G., Park, Eui-Soon, Su, Maohan, Cheppali, Sudheer Kumar, Cheemarla, Nagarjuna R., Kumar, Pradeep, Uchil, Pradeep D., Grover, Jonathan R., Foxman, Ellen F., Brown, Chelsea M., Stansfeld, Phillip J., Bewersdorf, Joerg, Mothes, Walther, Karatekin, Erdem, Wilen, Craig B., MacMicking, John D.

“…Understanding protective immunity to COVID-19 facilitates preparedness for future pandemics and combats new SARS-CoV-2 variants emerging in the human…”
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Early Extubation After Elective Infratentorial Craniotomy: Results of the International PRICE Survey by Gaudet, John G., Levy, Camille S., Jakus, Lien, Goettel, Nicolai, Meling, Torstein R., Quintard, Hervé

“…Background: Early extubation, defined as removal of the endotracheal tube at the end of surgery before transfer to a designated postoperative care area, is…”
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Prolonged Opioid Use and Pain Outcome and Associated Factors after Surgery under General Anesthesia: A Prospective Cohort Association Multicenter Study by Kuck, Kai, Naik, Bhiken I., Domino, Karen B., Posner, Karen L., Saager, Leif, Stuart, Ami R., Johnson, Ken B., Alpert, Salome B., Durieux, Marcel E., Sinha, Anik K., Brummett, Chad M., Aziz, Michael F., Cummings, Kenneth C., Gaudet, John G., Kurz, Andrea, Rijsdijk, Mienke, Wanderer, Jonathan P., Pace, Nathan L.

“…There is insufficient prospective evidence regarding the relationship between surgical experience and prolonged opioid use and pain. The authors investigated…”
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Implementation of the Enhanced Recovery After Surgery (ERAS®) program in neurosurgery by Belouaer, Amani, Cossu, Giulia, Papadakis, Georgios E., Gaudet, John G., Perez, Maria-Helena, Chanez, Vivianne, Boegli, Yann, Mury, Caroline, Peters, David, Addor, Valérie, Levivier, Marc, Daniel, Roy Thomas, Demartines, Nicolas, Messerer, Mahmoud

“…Background Over the past decade, Enhanced Recovery After Surgery (ERAS®) guidelines have been proven to simplify postoperative care and improve recovery in…”
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High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis by O'Meara, Teresa R, Duah, Kwamaa, Guo, Cynthia X, Maxson, Michelle E, Gaudet, Ryan G, Koselny, Kristy, Wellington, Melanie, Powers, Michael E, MacAlpine, Jessie, O'Meara, Matthew J, Veri, Amanda O, Grinstein, Sergio, Noble, Suzanne M, Krysan, Damian, Gray-Owen, Scott D, Cowen, Leah E

“…The innate immune system is the first line of defense against invasive fungal infections. As a consequence, many successful fungal pathogens have evolved…”
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Comparison of two simple models for prediction of short term mortality in patients after severe traumatic brain injury by Rached, Mohamed A.K.B., Gaudet, John G., Delhumeau, Cecile, Walder, Bernhard

“…The subscale motor score of Glasgow Coma Scale (msGCS) and the Abbreviated Injury Score of head region (HAIS) are validated prognostic factors in traumatic…”
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Hypnosis-Assisted Awake Craniotomy for Eloquent Brain Tumors: Advantages and Pitfalls by Cossu, Giulia, Vandenbulcke, Alberto, Zaccarini, Sonia, Gaudet, John G, Hottinger, Andreas F, Rimorini, Nina, Potie, Arnaud, Beaud, Valerie, Guerra-Lopez, Ursula, Daniel, Roy T, Berna, Chantal, Messerer, Mahmoud

“…Awake craniotomy (AC) is recommended for the resection of tumors in eloquent areas. It is traditionally performed under monitored anesthesia care (MAC), which…”
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