Search Results - "Gatsiou, Aikaterini"

RNA Therapeutics in Cardiovascular Precision Medicine by Laina, Ageliki, Gatsiou, Aikaterini, Georgiopoulos, Georgios, Stamatelopoulos, Kimon, Stellos, Konstantinos

“…Since our knowledge on structure and function of messenger RNA (mRNA) has expanded from merely being an intermediate molecule between DNA and proteins to the…”
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Endothelial dysfunction and immunothrombosis in sepsis by Maneta, Eleni, Aivalioti, Evmorfia, Tual-Chalot, Simon, Emini Veseli, Besa, Gatsiou, Aikaterini, Stamatelopoulos, Kimon, Stellos, Konstantinos

“…Sepsis is a life-threatening clinical syndrome characterized by multiorgan dysfunction caused by a dysregulated or over-reactive host response to infection…”
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Increased adenosine-to-inosine RNA editing in rheumatoid arthritis by Vlachogiannis, Nikolaos I., Gatsiou, Aikaterini, Silvestris, Domenico Alessandro, Stamatelopoulos, Kimon, Tektonidou, Maria G., Gallo, Angela, Sfikakis, Petros P., Stellos, Konstantinos

“…Adenosine-to-inosine (A-to-I) RNA editing of Alu retroelements is a primate-specific mechanism mediated by adenosine deaminases acting on RNA (ADARs) that…”
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Interleukin-17A Triggers the Release of Platelet-Derived Factors Driving Vascular Endothelial Cells toward a Pro-Angiogenic State by Gatsiou, Aikaterini, Sopova, Kateryna, Tselepis, Alexandros, Stellos, Konstantinos

“…Platelets comprise a highly interactive immune cell subset of the circulatory system traditionally known for their unique haemostatic properties. Although…”
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Amyloid-Beta (1-40) and the Risk of Death From Cardiovascular Causes in Patients With Coronary Heart Disease by Stamatelopoulos, Kimon, MD, Sibbing, Dirk, MD, Rallidis, Loukianos S., MD, Georgiopoulos, Georgios, MD, Stakos, Dimitrios, MD, Braun, Siegmund, MD, Gatsiou, Aikaterini, BSc, Sopova, Kateryna, MD, Kotakos, Christos, MD, Varounis, Christos, MD, Tellis, Constantinos C., PhD, Kastritis, Efstathios, MD, Alevizaki, Maria, MD, Tselepis, Alexandros D., MD, PhD, Alexopoulos, Panagiotis, MD, Laske, Christoph, MD, Keller, Till, MD, Kastrati, Adnan, MD, Dimmeler, Stefanie, PhD, Zeiher, Andreas M., MD, Stellos, Konstantinos, MD

“…Abstract Background The amyloid beta peptide is the major protein constituent of neuritic plaques in Alzheimer disease and appears to play a central role in…”
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Effector T cell chemokine IP-10 predicts cardiac recovery and clinical outcomes post-myocardial infarction by Sopova, Kateryna, Tual-Chalot, Simon, Mueller-Hennessen, Matthias, Vlachogiannis, Nikolaos I, Georgiopoulos, Georgios, Biener, Moritz, Sachse, Marco, Turchinovich, Andrey, Polycarpou-Schwarz, Maria, Spray, Luke, Maneta, Eleni, Bennaceur, Karim, Mohammad, Ashfaq, Richardson, Gavin David, Gatsiou, Aikaterini, Langer, Harald F, Frey, Norbert, Stamatelopoulos, Kimon, Heineke, Joerg, Duerschmied, Daniel, Giannitsis, Evangelos, Spyridopoulos, Ioakim, Stellos, Konstantinos

“…Preclinical data suggest that activation of the adaptive immune system is critical for myocardial repair processes in acute myocardial infarction. The aim of…”
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Clinical frailty, and not features of acute infection, is associated with late mortality in COVID‐19: a retrospective cohort study by Vlachogiannis, Nikolaos I., Baker, Kenneth F., Georgiopoulos, Georgios, Lazaridis, Charalampos, Loeff, Ina Schim, Hanrath, Aidan T., Sopova, Kateryna, Tual‐Chalot, Simon, Gatsiou, Aikaterini, Spyridopoulos, Ioakim, Stamatelopoulos, Kimon, Duncan, Christopher J.A., Stellos, Konstantinos

“…Background Coronavirus disease 2019 (COVID‐19) is associated with excess mortality after hospital discharge. Identification of patients at increased risk of…”
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MicroRNAs in platelet biogenesis and function: implications in vascular homeostasis and inflammation by Gatsiou, Aikaterini, Boeckel, Jes-Niels, Randriamboavonjy, Voahanginirina, Stellos, Konstantinos

“…Platelets are involved in vascular homeostasis and inflammation through interaction with circulating blood cells and vascular wall. MiRNAs are small, conserved…”
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RNA modifications in cardiovascular health and disease by Gatsiou, Aikaterini, Stellos, Konstantinos

“…RNA is not always a faithful copy of DNA. Advances in tools enabling the interrogation of the exact RNA sequence have permitted revision of how genetic…”
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RNA Editing Therapeutics: Advances, Challenges and Perspectives on Combating Heart Disease by Birgaoanu, Maria, Sachse, Marco, Gatsiou, Aikaterini

“…Cardiovascular disease still remains the leading cause of morbidity and mortality worldwide. Current pharmacological or interventional treatments help to…”
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Dawn of Epitranscriptomic Medicine by Gatsiou, Aikaterini, Stellos, Konstantinos

“…Medicine is at the crossroads of expanding disciplines. Prompt adaptation of medicine to each rapidly advancing research field, bridging bench to bedside, is a…”
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RNA-binding proteins in vascular inflammation and atherosclerosis by Sachse, Marco, Tual-Chalot, Simon, Ciliberti, Giorgia, Amponsah-Offeh, Michael, Stamatelopoulos, Kimon, Gatsiou, Aikaterini, Stellos, Konstantinos

“…Atherosclerotic cardiovascular disease (ASCVD) remains the major cause of premature death and disability worldwide, even when patients with an established…”
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Adenosine-to-inosine Alu RNA editing controls the stability of the pro-inflammatory long noncoding RNA NEAT1 in atherosclerotic cardiovascular disease by Vlachogiannis, Nikolaos I., Sachse, Marco, Georgiopoulos, Georgios, Zormpas, Eleftherios, Bampatsias, Dimitrios, Delialis, Dimitrios, Bonini, Francesca, Galyfos, George, Sigala, Fragiska, Stamatelopoulos, Kimon, Gatsiou, Aikaterini, Stellos, Konstantinos

“…Long non-coding RNAs (lncRNAs) have emerged as critical regulators in human disease including atherosclerosis. However, the mechanisms involved in the…”
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Adenosine-to-inosine RNA editing controls cathepsin S expression in atherosclerosis by enabling HuR-mediated post-transcriptional regulation by Stellos, Konstantinos, Gatsiou, Aikaterini, Stamatelopoulos, Kimon, Perisic Matic, Ljubica, John, David, Lunella, Federica Francesca, Jaé, Nicolas, Rossbach, Oliver, Amrhein, Carolin, Sigala, Frangiska, Boon, Reinier A, Fürtig, Boris, Manavski, Yosif, You, Xintian, Uchida, Shizuka, Keller, Till, Boeckel, Jes-Niels, Franco-Cereceda, Anders, Maegdefessel, Lars, Chen, Wei, Schwalbe, Harald, Bindereif, Albrecht, Eriksson, Per, Hedin, Ulf, Zeiher, Andreas M, Dimmeler, Stefanie

“…RNA editing by the adenosine deaminase ADAR1 controls cathepsin S expression in endothelial cells, a mechanism that is implicated in determining cathepsin S…”
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Increased myeloperoxidase plasma levels in patients with Alzheimer's disease by Tzikas, Stergios, Schlak, Dennis, Sopova, Kateryna, Gatsiou, Aikaterini, Stakos, Dimitrios, Stamatelopoulos, Kimon, Stellos, Konstantinos, Laske, Christoph

“…Increasing evidence supports the role of cardiovascular risk factors in the development of Alzheimer's disease (AD). In the present pilot study, we…”
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Additive contribution of microRNA-34a/b/c to human arterial ageing and atherosclerosis by Gatsiou, Aikaterini, Georgiopoulos, Georgios, Vlachogiannis, Nikolaos I., Pfisterer, Larissa, Fischer, Ariane, Sachse, Marco, Laina, Ageliki, Bonini, Francesca, Delialis, Dimitrios, Tual-Chalot, Simon, Zormpas, Eleftherios, Achangwa, Rawlings, Jiang, Longchang, Kontogiannis, Christos, Patras, Raphael, Hermeking, Heiko, Zeiher, Andreas M., Stamatelopoulos, Kimon, Dimmeler, Stefanie, Stellos, Konstantinos

“…Preclinical data suggest that the ageing-induced miR-34a regulates vascular senescence. Herein we sought to assess whether the miR-34 family members miR-34a,…”
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Cathepsin S Levels and Survival Among Patients With Non-ST-Segment Elevation Acute Coronary Syndromes by Stamatelopoulos, Kimon, Mueller-Hennessen, Matthias, Georgiopoulos, Georgios, Lopez-Ayala, Pedro, Sachse, Marco, Vlachogiannis, Nikolaos I., Sopova, Kateryna, Delialis, Dimitrios, Bonini, Francesca, Patras, Raphael, Ciliberti, Giorgia, Vafaie, Mehrshad, Biener, Moritz, Boeddinghaus, Jasper, Nestelberger, Thomas, Koechlin, Luca, Tual-Chalot, Simon, Kanakakis, Ioannis, Gatsiou, Aikaterini, Katus, Hugo, Spyridopoulos, Ioakim, Mueller, Christian, Giannitsis, Evangelos, Stellos, Konstantinos

“…Patients with non–ST-segment elevation acute coronary syndromes (NSTE-ACS) are at high residual risk for long-term cardiovascular (CV) mortality. Cathepsin S…”
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Amyloid-Beta (1-40) Peptide and Subclinical Cardiovascular Disease by Stamatelopoulos, Kimon, Pol, Christine J., Ayers, Colby, Georgiopoulos, Georgios, Gatsiou, Aikaterini, Brilakis, Emmanouil S., Khera, Amit, Drosatos, Konstantinos, de Lemos, James A., Stellos, Konstantinos

“…Subclinical cardiovascular disease was assessed by: 1) markers of cardiac function and structure by cardiovascular magnetic resonance imaging (Achieva, Philips…”
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Amyloid-β (1-40) and Mortality in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome: A Cohort Study by Stamatelopoulos, Kimon, Mueller-Hennessen, Matthias, Georgiopoulos, Georgios, Sachse, Marco, Boeddinghaus, Jasper, Sopova, Kateryna, Gatsiou, Aikaterini, Amrhein, Carolin, Biener, Moritz, Vafaie, Mehrshad, Athanasouli, Fani, Stakos, Dimitrios, Pateras, Konstantinos, Twerenbold, Raphael, Badertscher, Patrick, Nestelberger, Thomas, Dimmeler, Stefanie, Katus, Hugo A, Zeiher, Andreas M, Mueller, Christian, Giannitsis, Evangelos, Stellos, Konstantinos

“…Amyloid-β (1-40) (Aβ40) is implicated in mechanisms related to plaque destabilization and correlates with adverse outcomes in stable coronary artery disease…”
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Adenosine-to-inosine RNA editing contributes to type I interferon responses in systemic sclerosis by Vlachogiannis, Nikolaos I., Tual-Chalot, Simon, Zormpas, Eleftherios, Bonini, Francesca, Ntouros, Panagiotis A., Pappa, Maria, Bournia, Vasiliki-Kalliopi, Tektonidou, Maria G., Souliotis, Vassilis L., Mavragani, Clio P., Stamatelopoulos, Kimon, Gatsiou, Aikaterini, Sfikakis, Petros P., Stellos, Konstantinos

“…Adenosine deaminase acting on RNA-1 (ADAR1) enzyme is a type I interferon (IFN)-stimulated gene (ISG) catalyzing the deamination of adenosine-to-inosine, a…”
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