Search Results - "Gates, Keith P."
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CoRest1 regulates neurogenesis in a stage‐dependent manner
Published in Developmental dynamics (01-10-2019)“…Background Developmental processes, including neuronal differentiation, require precise regulation of transcription. The RE‐1 silencing transcription factor…”
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Endoderm Jagged induces liver and pancreas duct lineage in zebrafish
Published in Nature communications (03-10-2017)“…Liver duct paucity is characteristic of children born with Alagille Syndrome (ALGS), a disease associated with JAGGED1 mutations. Here, we report that…”
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Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes
Published in eLife (07-04-2017)“…The evolutionary origins of the hypoxia-sensitive cells that trigger amniote respiratory reflexes - carotid body glomus cells, and 'pulmonary neuroendocrine…”
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Apoc2 loss-of-function zebrafish mutant as a genetic model of hyperlipidemia
Published in Disease models & mechanisms (01-08-2015)“…Apolipoprotein C-II (APOC2) is an obligatory activator of lipoprotein lipase. Human patients with APOC2 deficiency display severe hypertriglyceridemia while…”
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Specification of hepatopancreas progenitors in zebrafish by hnf1ba and wnt2bb
Published in Development (Cambridge) (01-07-2013)“…Although the liver and ventral pancreas are thought to arise from a common multipotent progenitor pool, it is unclear whether these progenitors of the…”
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Regenerative failure of intrahepatic biliary cells in Alagille syndrome rescued by elevated Jagged/Notch/Sox9 signaling
Published in Proceedings of the National Academy of Sciences - PNAS (13-12-2022)“…Despite the robust healing capacity of the liver, regenerative failure underlies numerous hepatic diseases, including the haploinsufficient disorder, Alagille…”
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Intrahepatic cholangiocyte regeneration from an Fgf‐dependent extrahepatic progenitor niche in a zebrafish model of Alagille Syndrome
Published in Hepatology (Baltimore, Md.) (01-03-2022)“…Background and Aims Alagille Syndrome (ALGS) is a congenital disorder caused by mutations in the Notch ligand gene JAGGED1, leading to neonatal loss of…”
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The transcriptional repressor REST/NRSF modulates hedgehog signaling
Published in Developmental biology (15-04-2010)“…The spatial and temporal control of gene expression is key to generation of specific cellular fates during development. Studies of the transcriptional…”
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Expression and regulation of the zinc finger transcription factor Churchill during zebrafish development
Published in Gene Expression Patterns (01-06-2007)“…During gastrulation dynamic cell movements establish the germ layers and shape the body axis of the vertebrate embryo. The zinc finger protein Churchill (…”
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The transcriptional repressor REST regulates Sonic Hedgehog signaling during zebrafish development
Published in Developmental biology (15-07-2008)Get full text
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