Search Results - "Gates, Brooke L."

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  1. 1

    CaBagE: A Cas9-based Background Elimination strategy for targeted, long-read DNA sequencing by Wallace, Amelia D, Sasani, Thomas A, Swanier, Jordan, Gates, Brooke L, Greenland, Jeff, Pedersen, Brent S, Varley, Katherine E, Quinlan, Aaron R

    Published in PloS one (08-04-2021)
    “…A substantial fraction of the human genome is difficult to interrogate with short-read DNA sequencing technologies due to paralogy, complex haplotype…”
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    Journal Article
  2. 2

    Effect of graphene-based nanomaterials on corneal wound healing in vitro by Fukuto, Atsuhiko, Kang, Jennifer, Gates, Brooke L., Sannajust, Kimberley, Pinkerton, Kent E., Van Winkle, Laura S., Kiuchi, Yoshiaki, Leonard, Brian C., Thomasy, Sara M.

    Published in Experimental eye research (01-04-2023)
    “…Graphene-based nanomaterials (GBNs) are widely used due to their chemical and physical properties for multiple commercial and environmental applications. From…”
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  3. 3

    Metallic Engineered Nanomaterials and Ocular Toxicity: A Current Perspective by Cosert, Krista M, Kim, Soohyun, Jalilian, Iman, Chang, Maggie, Gates, Brooke L, Pinkerton, Kent E, Van Winkle, Laura S, Raghunathan, Vijay Krishna, Leonard, Brian C, Thomasy, Sara M

    Published in Pharmaceutics (03-05-2022)
    “…The ocular surface, comprised of the transparent cornea, conjunctiva, and protective tear film, forms a protective barrier defending deeper structures of the…”
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    Journal Article
  4. 4

    CRIPTO antagonist ALK4L75A-Fc inhibits breast cancer cell plasticity and adaptation to stress by Balcioglu, Ozlen, Heinz, Richard E, Freeman, David W, Gates, Brooke L, Hagos, Berhane M, Booker, Evan, Mirzaei Mehrabad, Elnaz, Diesen, Hyrum T, Bhakta, Kishan, Ranganathan, Supraja, Kachi, Masami, Leblanc, Mathias, Gray, Peter C, Spike, Benjamin T

    Published in Breast cancer research : BCR (13-11-2020)
    “…Abstract Background CRIPTO is a multi-functional signaling protein that promotes stemness and oncogenesis. We previously developed a CRIPTO antagonist, ALK4…”
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    Journal Article
  5. 5

    Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation by Balcioglu, Ozlen, Gates, Brooke L., Freeman, David W., Hagos, Berhane M., Mehrabad, Elnaz Mirzaei, Ayala-Talavera, David, Spike, Benjamin T.

    Published in NPJ breast cancer (14-09-2024)
    “…Cell state control is crucial for normal tissue development and cancer cell mimicry of stem/progenitor states, contributing to tumor heterogeneity, therapy…”
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  6. 6

    Transcorneal delivery of topically applied silver nanoparticles does not delay epithelial wound healing by Kim, Soohyun, Gates, Brooke L., Chang, Maggie, Pinkerton, Kent E., Van Winkle, Laura, Murphy, Christopher J., Leonard, Brian C., Demokritou, Philip, Thomasy, Sara M.

    Published in NanoImpact (01-10-2021)
    “…Silver nanoparticles (AgNPs) are a common antimicrobial additive for a variety of applications, including wound care. However, AgNPs often undergo dissolution…”
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  7. 7

    Metal Oxide Engineered Nanomaterials Modulate Rabbit Corneal Fibroblast to Myofibroblast Transformation by Fukuto, Atsuhiko, Kim, Soohyun, Kang, Jennifer, Gates, Brooke L, Chang, Maggie W, Pinkerton, Kent E, Van Winkle, Laura S, Kiuchi, Yoshiaki, Murphy, Christopher J, Leonard, Brian C, Thomasy, Sara M

    Published in Translational vision science & technology (18-10-2021)
    “…Corneal keratocyte-fibroblast-myofibroblast (KFM) transformation plays a critical role in corneal stromal wound healing. However, the impact of engineered…”
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  8. 8

    Engineered metal oxide nanomaterials inhibit corneal epithelial wound healing in vitro and in vivo by Kim, Soohyun, Gates, Brooke L., Leonard, Brian C., Gragg, Megan M., Pinkerton, Kent E., Van Winkle, Laura S., Murphy, Christopher J., Pyrgiotakis, Georgios, Zhang, Zhenyuan, Demokritou, Philip, Thomasy, Sara M.

    Published in NanoImpact (01-01-2020)
    “…Ocular exposure to metal oxide engineered nanomaterials (ENMs) is common as exemplified by zinc(II) oxide (ZnO), a major constituent of sunscreens and…”
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  9. 9

    Abstract 6958: CRIPTO-regulated extracellular vesicles mediate heterotypic cellular crosstalk in triple negative breast cancers by Freeman, David W., Gates, Brooke L., Spendlove, Mauri D., Spike, Benjamin T.

    Published in Cancer research (Chicago, Ill.) (22-03-2024)
    “…Abstract Tumor progression involves dynamic interaction between various cell types within the tumor microenvironment. Fibroblasts, which normally participate…”
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  10. 10

    Abstract 251: MCAM controls mammary cell state in luminal progenitor-derived breast cancer and alveologenesis by Gates, Brooke L., Balcioglu, Ozlen, Freeman, David W., Hagos, Berhane M., Spike, Benjamin T.

    Published in Cancer research (Chicago, Ill.) (22-03-2024)
    “…Abstract To establish and maintain functional and properly formed tissues, cells must integrate cues from their environment into fate decisions. External…”
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  11. 11

    Abstract 1531: CD146 couples and sequesters regulatory kinases to control breast cancer cell state plasticity by Balcioglu, Ozlen, Gates, Brooke L., Freeman, David W., Hagos, Berhane M., Spike, Benjamin T.

    Published in Cancer research (Chicago, Ill.) (15-06-2022)
    “…Abstract CD146 (Mcam; Muc18; s-endo; and gicerin) is an integral membrane glycoprotein originally identified in a human malignant melanoma, but mis-expressed…”
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  12. 12

    CRIPTO antagonist ALK4 L75A -Fc inhibits breast cancer cell plasticity and adaptation to stress by Balcioglu, Ozlen, Heinz, Richard E, Freeman, David W, Gates, Brooke L, Hagos, Berhane M, Booker, Evan, Mirzaei Mehrabad, Elnaz, Diesen, Hyrum T, Bhakta, Kishan, Ranganathan, Supraja, Kachi, Masami, Leblanc, Mathias, Gray, Peter C, Spike, Benjamin T

    Published in Breast cancer research : BCR (13-11-2020)
    “…CRIPTO is a multi-functional signaling protein that promotes stemness and oncogenesis. We previously developed a CRIPTO antagonist, ALK4 -Fc, and showed that…”
    Get full text
    Journal Article