Search Results - "Gates, Brooke L."
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CaBagE: A Cas9-based Background Elimination strategy for targeted, long-read DNA sequencing
Published in PloS one (08-04-2021)“…A substantial fraction of the human genome is difficult to interrogate with short-read DNA sequencing technologies due to paralogy, complex haplotype…”
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Effect of graphene-based nanomaterials on corneal wound healing in vitro
Published in Experimental eye research (01-04-2023)“…Graphene-based nanomaterials (GBNs) are widely used due to their chemical and physical properties for multiple commercial and environmental applications. From…”
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Metallic Engineered Nanomaterials and Ocular Toxicity: A Current Perspective
Published in Pharmaceutics (03-05-2022)“…The ocular surface, comprised of the transparent cornea, conjunctiva, and protective tear film, forms a protective barrier defending deeper structures of the…”
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CRIPTO antagonist ALK4L75A-Fc inhibits breast cancer cell plasticity and adaptation to stress
Published in Breast cancer research : BCR (13-11-2020)“…Abstract Background CRIPTO is a multi-functional signaling protein that promotes stemness and oncogenesis. We previously developed a CRIPTO antagonist, ALK4…”
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Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation
Published in NPJ breast cancer (14-09-2024)“…Cell state control is crucial for normal tissue development and cancer cell mimicry of stem/progenitor states, contributing to tumor heterogeneity, therapy…”
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Transcorneal delivery of topically applied silver nanoparticles does not delay epithelial wound healing
Published in NanoImpact (01-10-2021)“…Silver nanoparticles (AgNPs) are a common antimicrobial additive for a variety of applications, including wound care. However, AgNPs often undergo dissolution…”
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Metal Oxide Engineered Nanomaterials Modulate Rabbit Corneal Fibroblast to Myofibroblast Transformation
Published in Translational vision science & technology (18-10-2021)“…Corneal keratocyte-fibroblast-myofibroblast (KFM) transformation plays a critical role in corneal stromal wound healing. However, the impact of engineered…”
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Engineered metal oxide nanomaterials inhibit corneal epithelial wound healing in vitro and in vivo
Published in NanoImpact (01-01-2020)“…Ocular exposure to metal oxide engineered nanomaterials (ENMs) is common as exemplified by zinc(II) oxide (ZnO), a major constituent of sunscreens and…”
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Abstract 6958: CRIPTO-regulated extracellular vesicles mediate heterotypic cellular crosstalk in triple negative breast cancers
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract Tumor progression involves dynamic interaction between various cell types within the tumor microenvironment. Fibroblasts, which normally participate…”
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Abstract 251: MCAM controls mammary cell state in luminal progenitor-derived breast cancer and alveologenesis
Published in Cancer research (Chicago, Ill.) (22-03-2024)“…Abstract To establish and maintain functional and properly formed tissues, cells must integrate cues from their environment into fate decisions. External…”
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Abstract 1531: CD146 couples and sequesters regulatory kinases to control breast cancer cell state plasticity
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract CD146 (Mcam; Muc18; s-endo; and gicerin) is an integral membrane glycoprotein originally identified in a human malignant melanoma, but mis-expressed…”
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CRIPTO antagonist ALK4 L75A -Fc inhibits breast cancer cell plasticity and adaptation to stress
Published in Breast cancer research : BCR (13-11-2020)“…CRIPTO is a multi-functional signaling protein that promotes stemness and oncogenesis. We previously developed a CRIPTO antagonist, ALK4 -Fc, and showed that…”
Get full text
Journal Article