Search Results - "Gastinel, Louis"

B7-H6/NKp30 interaction: a mechanism of alerting NK cells against tumors by Kaifu, Tomonori, Escalière, Bertrand, Gastinel, Louis N., Vivier, Eric, Baratin, Myriam

“…Natural killer (NK) cells are lymphocytes of the innate immune system that sense target cells through a panel of activating and inhibitory receptors. Together…”
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Tuning of Natural Killer Cell Reactivity by NKp46 and Helios Calibrates T Cell Responses by Narni-Mancinelli, Emilie, Jaeger, Baptiste N., Bernat, Claire, Fenis, Aurore, Kung, Sam, De Gassart, Aude, Mahmood, Sajid, Gut, Marta, Heath, Simon C., Estellé, Jordi, Bertosio, Elodie, Vely, Frédéric, Gastinel, Louis N., Beutler, Bruce, Malissen, Bernard, Malissen, Marie, Gut, Ivo G., Vivier, Eric, Ugolini, Sophie

“…Natural killer (NK) cells are lymphocytes involved in antimicrobial and antitumoral immune responses. Using N-ethyl-N-nitrosourea mutagenesis in mice, we…”
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Crystal structures of the bovine β4galactosyltransferase catalytic domain and its complex with uridine diphosphogalactose by Gastinel, Louis Noél, Cambillau, Christian, Bourne, Yves

“…β1,4‐galactosyltransferase T1 (β4Gal‐T1, EC 2.4.1.90/38), a Golgi resident membrane‐bound enzyme, transfers galactose from uridine diphosphogalactose to the…”
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Calcineurin activity assay measurement by liquid chromatography-tandem mass spectrometry in the multiple reaction monitoring mode by Carr, Lynn, Gagez, Anne-Laure, Essig, Marie, Sauvage, François-Ludovic, Marquet, Pierre, Gastinel, Louis Noel

“…Blood concentrations of the calcineurin inhibitors (CNIs) cyclosporine and tacrolimus are currently measured to monitor immunosuppression in transplant…”
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Amino acid substitutions at the major insertion loop of Candida albicans sterol 14alpha-demethylase are involved in fluconazole resistance by Alvarez-Rueda, Nidia, Fleury, Audrey, Morio, Florent, Pagniez, Fabrice, Gastinel, Louis, Le Pape, Patrice

“…In the fungal pathogen Candida albicans, amino acid substitutions of 14alpha-demethylase (CaErg11p, CaCYP51) are associated with azole antifungals resistance…”
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Bovine α1,3-galactosyltransferase catalytic domain structure and its relationship with ABO histo-blood group and glycosphingolipid glycosyltransferases by Gastinel, Louis N., Bignon, Christophe, Misra, Anup K., Hindsgaul, Ole, Shaper, Joel H., Joziasse, David H.

“…α1,3‐galactosyltransferase (α3GalT, EC 2.4.1.151) is a Golgi‐resident, type II transmembrane protein that transfers galactose from UDP‐α‐galactose to the…”
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Untargeted screening of urinary peptides with liquid chromatography coupled to hybrid linear-ion trap tandem mass spectrometry by Sauvage, François-Ludovic, Gastinel, Louis Noël, Marquet, Pierre

“…► The procedure can detect and identify peptides and their inferred parent proteins. ► The structure of some peptides can generally be resolved from their EPI…”
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Generation of llama single-domain antibodies against methotrexate, a prototypical hapten by Alvarez-Rueda, Nidia, Behar, Ghislaine, Ferré, Virginie, Pugnière, Martine, Roquet, Françoise, Gastinel, Louis, Jacquot, Catherine, Aubry, Jacques, Baty, Daniel, Barbet, Jacques, Birklé, Stéphane

“…Single-domain antibodies specific to methotrexate (MTX) were obtained after immunization of one llama ( Llama glama). Specific VHH domains (V–D–J-REGION) were…”
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Crystal structure of the human natural killer cell activating receptor KIR2DS2 (CD158j) by Saulquin, Xavier, Gastinel, Louis N, Vivier, Eric

“…Killer cell Ig-like receptors (KIRs) regulate the function of human natural killer and T cell subsets. A feature of the KIR locus is the clustering of…”
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Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex by Kissinger, Charles R, Parge, Hans E, Knighton, Daniel R, Lewis, Cristina T, Pelletier, Laura A, Tempczyk, Anna, Kalish, Vincent J, Tucker, Kathleen D, Showalter, Richard E, Moomaw, Ellen W, Gastinel, Louis N, Habuka, Noriyuki, Chen, Xinghai, Maldonado, Fausto, Barker, John E, Bacquet, Russell, Villafranca, J. Ernest

“…Calcineurin (CaN) is a calcium- and calmodulin-dependent protein serine/threonine phosphate which is critical for several important cellular processes,…”
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Objectives and applications of phenotyping network set-up for livestock by HOCQUETTE, Jean-François, CAPEL, Carine, DAVID, Valérie, GUÉMENÉ, Daniel, BIDANEL, Joël, PONSART, Claire, GASTINEL, Pierre-Louis, BAIL, Pierre-Yves Le, MONGET, Philippe, MORMÈDE, Pierre, BARBEZANT, Maurice, GUILLOU, Florian, PEYRAUD, Jean-Louis

“…ABSTRACT Providing phenotypic information, which is accurate, reliable, repeatable and comparable across countries or laboratories, is critical to gain a…”
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Crystal Structure of Hemolin: A Horseshoe Shape with Implications for Homophilic Adhesion by Su, Xiao-Dong, Gastinel, Louis N., Vaughn, Daniel E., Faye, Ingrid, Poon, Pak, Bjorkman, Pamela J.

“…Hemolin, an insect immunoglobulin superfamily member, is a lipopolysaccharide-binding immune protein induced during bacterial infection. The 3.1 angstrom…”
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Crystal structure at 2.2 Å resolution of the MHC-related neonatal Fc receptor by Burmeister, Wilhelm P, Gastinel, Louis N, Simister, Neil E, Blum, Michael L, Bjorkman, Pamela J

“…The three-dimensional structure of the rat neonatal Fc receptor (FcRn) is similar to the structure of molecules of the major histocompatibility complex (MHC)…”
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Expression patterns of LmAP2L1 and LmAP2L2 encoding two-APETALA2 domain proteins during somatic embryogenesis and germination of hybrid larch ( Larix× marschlinsii) by Guillaumot, Damien, Lelu-Walter, Marie-Anne, Germot, Agnès, Meytraud, Fanny, Gastinel, Louis, Riou-Khamlichi, Catherine

“…Two APETALA2 domain transcription factors were characterized first in angiosperms, and, recently, in several gymnosperms. These proteins are involved in…”
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A novel human glycosyltransferase: primary structure and characterization of the gene and transcripts by Heinonen, Taisto Y.K, Pasternack, Leena, Lindfors, Katri, Breton, Christelle, Gastinel, Louis N, Mäki, Markku, Kainulainen, Heikki

“…We report the identification and primary structure of a novel human glycosyltransferase, B3GTL (β3-glycosyltransferase-like). The 498 residue protein consists…”
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An efficient synthesis of GDP-hexanolamine, a key tool for the purification of fucosyltransferases by Vincent, Stéphane P, Gastinel, Louis N

“…A new efficient synthesis of GDP-hexanolamine from hexanolamine is reported with an overall yield of 71%. The pyrophosphate formation, the key step of this…”
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The class I major histocompatibility complex related Fc receptor shows pH-dependent stability differences correlating with immunoglobulin binding and release by Raghavan, Malini, Gastinel, Louis N, Bjorkman, Pamela J

“…Maternal immunoglobulin G (IgG) in milk is transported to the bloodstream of newborn rodents via an Fc receptor (FcRn) expressed in the gut. The receptor shows…”
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Expression and Crystallization of a Soluble and Functional Form of an Fc Receptor Related to Class I Histocompatibility Molecules by Gastinel, Louis N., Simister, Neil E., Bjorkman, Pamela J.

“…Maternal transport of immunoglobulin to the newborn mammal is important for immune defense during the first weeks of independent life. Receptors for the Fc…”
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Investigation of the interaction between the class I MHC-related Fc receptor and its immunoglobulin G ligand by Raghavan, M, Chen, M Y, Gastinel, L N, Bjorkman, P J

“…The neonatal Fc receptor (FcRn) is structurally similar to class I major histocompatibility molecules. FcRn transports maternal immunoglobulin G (IgG) from…”
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Molecular genetics of the chicken MHC: current status and evolutionary aspects by Kroemer, G, Bernot, A, Béhar, G, Chaussé, A M, Gastinel, L N, Guillemot, F, Park, I, Thoraval, P, Zoorob, R, Auffray, C

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