Search Results - "Gasser, S.M."

Automatic tracking of individual fluorescence particles: application to the study of chromosome dynamics by Sage, D., Neumann, F.R., Hediger, F., Gasser, S.M., Unser, M.

“…We present a new, robust, computational procedure for tracking fluorescent markers in time-lapse microscopy. The algorithm is optimized for finding the…”
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SIR3 and SIR4 proteins are required for the positioning and integrity of yeast telomeres by Palladino, F, Laroche, T, Gilson, E, Axelrod, A, Pillus, L, Gasser, S M

“…Heritable inactivation of genes occurs in specific chromosomal domains located at the silent mating type loci and at telomeres of S. cerevisiae. The SIR genes…”
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Casein kinase II phosphorylates the eukaryote-specific C-terminal domain of topoisomerase II in vivo by Cardenas, M.E, Dang, Q, Glover, C.V.C, Gasser, S.M

“…The decatenation activity of DNA topoisomerase II is essential for viability as eukaryotic cells traverse mitosis. Phosphorylation has been shown to stimulate…”
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The function of telomere clustering in yeast: the circe effect by Gasser, S M, Hediger, F, Taddei, A, Neumann, F R, Gartenberg, M R

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Scaffold attachment of DNA loops in metaphase chromosomes by Mirkovitch, J, Gasser, S M, Laemmli, U K

“…We have examined the higher-order loop organization of DNA in interphase nuclei and metaphase chromosomes from Drosophila Kc cells, and we detect no changes in…”
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Long-range compaction and flexibility of interphase chromatin in budding yeast analyzed by high-resolution imaging techniques by Bystricky, K, Heun, P, Gehlen, L, Langowski, J, Gasser, S.M

“…Little is known about how chromatin folds in its native state. Using optimized in situ hybridization and live imaging techniques have determined compaction…”
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Improved methods for the isolation of individual and clustered mitotic chromosomes by Gasser, S M, Laemmli, U K

“…We have optimized procedures for the isolation of mitotic chromosomes from tissue culture cells. The first procedure is a rapid method for obtaining…”
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Nutrition and the biology of human ageing: Molecular mechanisms underlying ageing by Gasser, S. M., Le Coutre, J.

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Preparation and characterization of yeast nuclear extracts for efficient RNA polymerase B (II)-dependent transcription in vitro by Verdier, J.M, Stalder, R, Roberge, M, Amati, B, Sentenac, A, Gasser, S.M

“…We present a reproducible method for the preparation of nuclear extracts from the yeast Saccharomyces cerevisiae that support efficient RNA polymerase B…”
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The positioning of yeast telomeres depends on SIR3, SIR4, and the integrity of the nuclear membrane by Palladino, F, Laroche, T, Gilson, E, Pillus, L, Gasser, S M

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The clustering of telomeres and colocalization with Rap1, Sir3, and Sir4 proteins in wild-type Saccharomyces cerevisiae by Gotta, M. (Swiss Institute for Experimental Cancer Research, Epalinges/Lausanne, Switzerland.), Laroche, T, Formenton, A, Maillet, L, Scherthan, H, Gasser, S.M

“…We have developed a novel technique for combined immunofluorescence/in situ hybridization on fixed budding yeast cells that maintains the three-dimensional…”
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Subtelomeric factors antagonize telomere anchoring and Tel1-independent telomere length regulation by Hediger, F, Berthiau, A.S, Houwe, G. van, Gilson, E, Gasser, S.M

“…Yeast telomeres are anchored at the nuclear envelope (NE) through redundant pathways that require the telomere‐binding factors yKu and Sir4. Significant…”
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Localization of Sir2p: the nucleolus as a compartment for silent information regulators by Gotta, M, Strahl-Bolsinger, S, Renauld, H, Laroche, T, Kennedy, B.K, Grunstein, M, Gasser, S.M

“…In wild-type budding yeast strains, the proteins encoded by SIR3, SIR4 and RAP1 co-localize with telomeric DNA in a limited number of foci in interphase…”
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telobox, a Myb-related telomeric DNA binding motif found in proteins from yeast, plants and human by Bilaud, T, Koering, C.E, Binet-Brasselet, E, Ancelin, K, Pollice, A, Gasser, S.M, Gilson, E

“…The yeast TTAGGG binding factor 1 (Tbf1) was identified and cloned through its ability to interact with vertebrate telomeric repeats in vitro. We show here…”
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The Dynamics of Yeast Telomeres and Silencing Proteins through the Cell Cycle by Laroche, Thierry, Martin, Sophie G., Tsai-Pflugfelder, Monika, Gasser, Susan M.

“…Genes integrated near the telomeres of budding yeast have a variegated pattern of gene repression that is mediated by the silent information regulatory…”
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Structural Maintenance of Chromosomes Protein C-terminal Domains Bind Preferentially to DNA with Secondary Structure by Akhmedov, Alexandre T., Frei, Christian, Tsai-Pflugfelder, Monika, Kemper, Börries, Gasser, Susan M., Jessberger, Rolf

“…Structural maintenance of chromosomes (SMC) proteins interact with DNA in chromosome condensation, sister chromatid cohesion, DNA recombination, and gene…”
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Taz1p and Teb1p, two telobox proteins in Schizosaccharomyces pombe, recognize different telomere-related DNA sequences by Vassetzky, N.S, Gaden, F, Brun, C, Gasser, S.M, Gilson, E

“…Band shift assays were used to study proteins from the fission yeast that bind double-stranded telomeric repeat sequences. We also examine general DNA binding…”
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Analysis of nuclear organization in Saccharomyces cerevisiae by Gotta, M, Laroche, T, Gasser, S M

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Cooperation at a distance between silencers and proto-silencers at the yeast HML locus by Boscheron, C, Maillet, L, Marcand, S, Tsai-Pflugfelder, M, Gasser, S.M, Gilson, E

“…Transcriptional repression at the silent yeast mating type loci is achieved through the formation of a particular nucleoprotein complex at specific cis-acting…”
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Wet oxidation of Ti 34Si 23N 43 thin films with and without pre-annealing by Kacsich, T., Gasser, S.M., Garland, C., Nicolet, M.-A.

“…Films of a ternary alloy of composition Ti 34Si 23N 43 and of a structure consisting of homogeneously distributed ∼2 nm sized TiN-like grains in an amorphous…”
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