Search Results - "Gasser, Harald"
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S -nitroso human serum albumin attenuates pulmonary hypertension, improves right ventricular–arterial coupling, and reduces oxidative stress in a chronic right ventricle volume overload model
Published in The Journal of heart and lung transplantation (01-03-2015)“…Background This study examined the acute effect of intravenous S -nitroso human serum albumin ( S -NO-HSA) infusion on overall hemodynamics and oxidative…”
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Continuous venovenous hemofiltration improves arterial oxygenation in endotoxin-induced lung injury in pigs
Published in Anesthesiology (Philadelphia) (01-08-2001)“…Hypoxemia is common in septic acute lung failure. Therapy is mainly supportive, and most trials using specific inhibitors of key inflammatory mediators (ie.,…”
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Protective effect of a novel NO-donor on ischemia/reperfusion injury in a rat epigastric flap model
Published in Wound repair and regeneration (01-01-2003)“…An altered metabolism of endothelial cell–derived nitric oxide has been implicated in the microvascular dysfunction associated with ischemia/reperfusion. The…”
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The nitric oxide donor, S-nitroso human serum albumin, as an adjunct to HTK-N cardioplegia improves protection during cardioplegic arrest after myocardial infarction in rats
Published in Interactive cardiovascular and thoracic surgery (01-03-2015)“…OBJECTIVES Currently available cardioplegic solutions provide excellent protection in patients with normal surgical risk; in high-risk patients, however, such…”
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Abstract 17487: S-Nitroso Human Serum Albumin (S-NO-HSA) Attenuates Pulmonary Hypertension, Improves Right Ventricular-Arterial Coupling and Reduces Oxidative Stress in a Chronic Right Ventricle Volume Overload Model
Published in Circulation (New York, N.Y.) (22-11-2011)“…Abstract only BACKGROUND The study was aimed to examine the acute overall hemodynamic and oxidative stress effects to intravenous S-NO-HSA infusion in a model…”
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S-nitroso human serum albumin reduces ischaemia/reperfusion injury in the pig heart after unprotected warm ischaemia
Published in Cardiovascular research (01-02-2008)“…Aims Uncoupled endothelial nitric oxide synthase (eNOS) is a major contributor to vascular reactive oxygen species generation in ischaemia/reperfusion (I/R)…”
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S-nitroso human serum albumin treatment reduces ischemia/reperfusion injury in skeletal muscle via nitric oxide release
Published in Circulation (New York, N.Y.) (25-06-2002)“…Peroxynitrite generated from nitric oxide (NO) and superoxide (O2-) contributes to ischemia/reperfusion (I/R) injury. Feedback inhibition of endothelial NO…”
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S-nitroso human serum albumin attenuates ischemia/reperfusion injury after cardioplegic arrest in isolated rabbit hearts
Published in The Journal of heart and lung transplantation (01-12-2005)“…Depletion of nitric oxide (NO) is associated with ischemia/reperfusion injury. The novel NO donor, S-nitroso human serum albumin (S-NO-HSA), could bridge NO…”
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The attenuation of hepatic microcirculatory alterations by exogenous substitution of nitric oxide by S-nitroso-human albumin after hemorrhagic shock in the rat
Published in Shock (Augusta, Ga.) (01-02-2004)“…Hepatic microcirculatory disorders such as narrowing of sinusoids after hemorrhagic shock play a major role in the pathogenesis of organ failure. It is known…”
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S-nitroso human serum albumin improves oxygen metabolism during reperfusion after severe myocardial ischemia
Published in Pharmacology (01-10-2004)“…Nitric oxide (NO) supplementation may modify myocardial oxygen consumption and vascular function after ischemia. We investigated the effects of the NO donor,…”
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Quinaprilat during cardioplegic arrest in the rabbit to prevent ischemia-reperfusion injury
Published in The Journal of thoracic and cardiovascular surgery (01-08-2002)“…Objectives: This study evaluated intracardiac angiotensin-converting enzyme inhibition as an adjuvant to cardioplegia and examined its effects on hemodynamic,…”
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Nitrosated human serum albumin - A novel no-donor studied during 6 hours of ischemia
Published in Journal of molecular and cellular cardiology (01-06-2002)Get full text
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Protection against endotoxemia in rats by a novel tetrahydrobiopterin analogue
Published in Shock (Augusta, Ga.) (01-05-2000)“…We studied the effects of a novel pterin antagonist of NO synthase, the 4-amino analogue of tetrahydrobiopterin (4-ABH4), in a rat model of endotoxic shock and…”
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Oxidatively modified plasma phospholipids containing reactive carbonyl functions measured by HPLC: evidence for phosphatidylcholine-bound aldehydes in plasma of burn patients
Published in Free radical research (01-01-1995)“…A HPLC method has been developed to measure phosphatidylcholine (PC) containing reactive carbonyl functions in the sn-acyl residue in order to study processes…”
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Influence of Parenteral Nutrition on Phospholipid Metabolism in Posttraumatic Rat Lungs
Published in JPEN. Journal of parenteral and enteral nutrition (01-11-1986)“…In the current investigation, we studied two groups of rats—one group supplied exogenous phospholipid precursors (carbohydrate plus fat emulsion group) and the…”
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Circulatory changes after prolonged ischemia in the epigastric flap
Published in Journal of reconstructive microsurgery (01-10-2001)“…The circulation system seems to have early encounters with pathophysiologic processes during ischemia and reperfusion, such as overproduction of oxygen…”
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