Search Results - "Gasque, P"

On the origin and development of glioblastoma: multifaceted role of perivascular mesenchymal stromal cells by Ah-Pine, F, Khettab, M, Bedoui, Y, Slama, Y, Daniel, M, Doray, B, Gasque, P

“…Glioblastoma, IDH wild-type is the most common and aggressive form of glial tumors. The exact mechanisms of glioblastoma oncogenesis, including the…”
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The role of primary infection of Schwann cells in the aetiology of infective inflammatory neuropathies by Neal, J.W, Gasque, P

“…Summary Numerous different pathogens are responsible for infective peripheral neuropathies and this is generally the result of the indirect effects of pathogen…”
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Innate immunity and protective neuroinflammation: new emphasis on the role of neuroimmune regulatory proteins by Griffiths, M, Neal, J W, Gasque, P

“…Brain inflammation due to infection, hemorrhage, and aging is associated with activation of the local innate immune system as expressed by infiltrating cells,…”
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Corrigendum to “The role of primary infection of Schwann cells in the aetiology of infective inflammatory neuropathies” [J Infect 73 (2016) 402–418] by Neal, J.W, Gasque, P

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Role of complement and complement regulators in the removal of apoptotic cells by Trouw, L.A., Blom, A.M., Gasque, P.

“…Apoptosis, followed by rapid phagocytic clearance, is the primary mechanism by which organisms dispose of unwanted cells. The intracellular and extracellular…”
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Structure-function studies of the receptors for complement C1q by McGreal, E, Gasque, P

“…C1q is an essential component of the phylogenetically ancient innate complement (C) system and is crucial to our natural ability to ward off infection and…”
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Increased Complement Biosynthesis By Microglia and Complement Activation on Neurons in Huntington's Disease by Singhrao, S.K, Neal, J.W, Morgan, B.P, Gasque, P

“…In this study complement activation and biosynthesis have been analysed in the brains of Huntington's disease (HD) (n=9) and normal (n=3) individuals. In HD…”
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Encephalitis due to emerging viruses: CNS innate immunity and potential therapeutic targets by Denizot, M, Neal, J.W, Gasque, P

“…Summary The emerging viruses represent a group of pathogens that are intimately connected to a diverse range of animal vectors. The recent escalation of air…”
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The Regulation of the CNS Innate Immune Response Is Vital for the Restoration of Tissue Homeostasis (Repair) after Acute Brain Injury: A Brief Review by Griffiths, M. R., Neal, J. W., Gasque, P.

“…Neurons and glia respond to acute injury by participating in the CNS innate immune response. This involves the recognition and clearance of “not self ”…”
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First screening of Aedes albopictus immunogenic salivary proteins by Doucoure, S., Cornelie, S., Patramool, S., Mouchet, F., Demettre, E., Seveno, M., Dehecq, J. S., Rutee, H., Herve, J. P., Favier, F., Missé, D., Gasque, P., Remoue, F.

“…Study of the human antibody (Ab) response to Aedes salivary proteins can provide new biomarkers to evaluate human exposure to vector bites. The identification…”
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Complement components of the innate immune system in health and disease in the CNS by Gasque, P., Dean, Y.D., McGreal, E.P., VanBeek, J., Morgan, B.P.

“…The innate immune system and notably the complement (C) system play important roles in host defense to recognise and kill deleterious invaders or toxic…”
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Complement: a unique innate immune sensor for danger signals by Gasque, Philippe

“…The complement (C) inflammatory cascade is part of the phylogenetically ancient innate immune response and is crucial to our natural ability to ward off…”
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Complement expression in human brain. Biosynthesis of terminal pathway components and regulators in human glial cells and cell lines by Gasque, P, Fontaine, M, Morgan, BP

“…C biosynthesis at extrahepatic sites remote from plasma C may be important in the protection of tissues against inflammation and infection but may also…”
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4CPS-242 Acute respiratory infections: an analysis of hospital antibiotherapy prescription quality for the paediatric population by Monforte Gasque, P, Lazaro Gallardo, EM, Lazaro Castellano, AM, Elviro Llorens, M, Maroto Garcia, E, Querol Hernandez, AC

“…Background and importanceIn the paediatric population, a potentially high use of antibiotics has been verified. The inappropriate use of these drugs leads to a…”
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Extrahepatic complement biosynthesis: where, when and why? by MORGAN, B. P., GASQUE, P.

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Expression of the receptor for complement C5a (CD88) is up-regulated on reactive astrocytes, microglia, and endothelial cells in the inflamed human central nervous system by Gasque, P, Singhrao, SK, Neal, JW, Gotze, O, Morgan, BP

“…C5a receptor (C5aR, CD88) is a receptor originally described on neutrophils and monocyte-macrophages but recently found on hepatocytes, epithelial cells,…”
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Complement regulatory protein expression by a human oligodendrocyte cell line: cytokine regulation and comparison with astrocytes by GASQUE, P., MORGAN, B. P.

“…Rat oligodendrocytes spontaneously activate complement (C) and lack the C inhibitor CD59. As a consequence, rat oligodendrocytes are susceptible to lysis by…”
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35 Tumor endothelial marker 1 (TEM1, endosialin) is expressed in functional and morphological distinct trophoblast cells in human and mouse placenta by Herzog, S.U.E, Gasque, P, Maul, H, Sinn, H.-P, Kashif, M, Kranz, C, Huntscha, S, Vinnikov, I, Nawroth, P.P, Isermann, B

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Identification and characterization of complement C3 receptors on human astrocytes by Gasque, P, Chan, P, Mauger, C, Schouft, MT, Singhrao, S, Dierich, MP, Morgan, BP, Fontaine, M

“…Astrocytes express C components and have been implicated as a major source of intrathecal C. To ascertain the effects of C activation on these cells, we have…”
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Expression of the complement classical pathway by human glioma in culture. A model for complement expression by nerve cells by Gasque, P, Ischenko, A, Legoedec, J, Mauger, C, Schouft, M T, Fontaine, M

“…In this paper we demonstrate the synthesis of the components of the classical complement pathway, namely C1q, C1r, C1s, C1-Inh, C2, C4, and C5, by human glioma…”
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