Search Results - "Gasperi, Christiane"

Vaccination frequency in people newly diagnosed with multiple sclerosis by Darvishi, Sonia, Donnachie, Ewan, Gasperi, Christiane, Hapfelmeier, Alexander, Hemmer, Bernhard

“…Background: Infections are discussed as risk factor for multiple sclerosis (MS) development and relapses. This may lead to decreased vaccination frequency in…”
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Association of pregnancies with risk of multiple sclerosis by Gasperi, Christiane, Hapfelmeier, Alexander, Schneider, Antonius, Kuhn, Klaus A, Donnachie, Ewan, Hemmer, Bernhard

“…Background: Pregnancies have an impact on the disease course of multiple sclerosis (MS), but their relationship with MS risk is yet unclear. Objective: To…”
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Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity by Hiltensperger, Michael, Beltrán, Eduardo, Kant, Ravi, Tyystjärvi, Sofia, Lepennetier, Gildas, Domínguez Moreno, Helena, Bauer, Isabel J., Grassmann, Simon, Jarosch, Sebastian, Schober, Kilian, Buchholz, Veit R., Kenet, Selin, Gasperi, Christiane, Öllinger, Rupert, Rad, Roland, Muschaweckh, Andreas, Sie, Christopher, Aly, Lilian, Knier, Benjamin, Garg, Garima, Afzali, Ali M., Gerdes, Lisa Ann, Kümpfel, Tania, Franzenburg, Sören, Kawakami, Naoto, Hemmer, Bernhard, Busch, Dirk H., Misgeld, Thomas, Dornmair, Klaus, Korn, Thomas

“…Multidimensional single-cell analyses of T cells have fueled the debate about whether there is extensive plasticity or ‘mixed’ priming of helper T cell subsets…”
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A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis by Madireddy, Lohith, Patsopoulos, Nikolaos A., Cotsapas, Chris, Bos, Steffan D., Beecham, Ashley, McCauley, Jacob, Kim, Kicheol, Jia, Xiaoming, Santaniello, Adam, Caillier, Stacy J., Andlauer, Till F. M., Barcellos, Lisa F., Berge, Tone, Bernardinelli, Luisa, Martinelli-Boneschi, Filippo, Booth, David R., Briggs, Farren, Celius, Elisabeth G., Comabella, Manuel, Comi, Giancarlo, Cree, Bruce A. C., D’Alfonso, Sandra, Dedham, Katrina, Duquette, Pierre, Dardiotis, Efthimios, Esposito, Federica, Fontaine, Bertrand, Gasperi, Christiane, Goris, An, Dubois, Bénédicte, Gourraud, Pierre-Antoine, Hadjigeorgiou, Georgios, Haines, Jonathan, Hawkins, Clive, Hemmer, Bernhard, Hintzen, Rogier, Horakova, Dana, Isobe, Noriko, Kalra, Seema, Kira, Jun-ichi, Khalil, Michael, Kockum, Ingrid, Lill, Christina M., Lincoln, Matthew R., Luessi, Felix, Martin, Roland, Oturai, Annette, Palotie, Aarno, Pericak-Vance, Margaret A., Henry, Roland, Saarela, Janna, Ivinson, Adrian, Olsson, Tomas, Taylor, Bruce V., Stewart, Graeme J., Harbo, Hanne F., Compston, Alastair, Hauser, Stephen L., Hafler, David A., Zipp, Frauke, De Jager, Philip, Sawcer, Stephen, Oksenberg, Jorge R., Baranzini, Sergio E.

“…Genome-wide association studies (GWAS) have identified more than 50,000 unique associations with common human traits. While this represents a substantial step…”
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Gray matter atrophy in relapsing-remitting multiple sclerosis is associated with white matter lesions in connecting fibers by Bussas, Matthias, Grahl, Sophia, Pongratz, Viola, Berthele, Achim, Gasperi, Christiane, Andlauer, Till, Gaser, Christian, Kirschke, Jan S, Wiestler, Benedikt, Zimmer, Claus, Hemmer, Bernhard, Mühlau, Mark

“…Background: Lesions of brain white matter (WM) and atrophy of brain gray matter (GM) are well-established surrogate parameters in multiple sclerosis (MS), but…”
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Association of the retinal vasculature, intrathecal immunity, and disability in multiple sclerosis by Noll, Christina, Hiltensperger, Michael, Aly, Lilian, Wicklein, Rebecca, Afzali, Ali Maisam, Mardin, Christian, Gasperi, Christiane, Berthele, Achim, Hemmer, Bernhard, Korn, Thomas, Knier, Benjamin

“…Background Optical coherence tomography angiography (OCT-A) is a novel technique allowing non-invasive assessment of the retinal vasculature. During relapsing…”
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Shared associations identify causal relationships between gene expression and immune cell phenotypes by Gasperi, Christiane, Chun, Sung, Sunyaev, Shamil R., Cotsapas, Chris

“…Genetic mapping studies have identified thousands of associations between common variants and hundreds of human traits. Translating these associations into…”
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Retrospective cohort study to devise a treatment decision score predicting adverse 24-month radiological activity in early multiple sclerosis by Hapfelmeier, Alexander, On, Begum Irmak, Mühlau, Mark, Kirschke, Jan S., Berthele, Achim, Gasperi, Christiane, Mansmann, Ulrich, Wuschek, Alexander, Bussas, Matthias, Boeker, Martin, Bayas, Antonios, Senel, Makbule, Havla, Joachim, Kowarik, Markus C., Kuhn, Klaus, Gatz, Ingrid, Spengler, Helmut, Wiestler, Benedikt, Grundl, Lioba, Sepp, Dominik, Hemmer, Bernhard

“…Background: Multiple sclerosis (MS) is a chronic neuroinflammatory disease affecting about 2.8 million people worldwide. Disease course after the most common…”
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B cell-directed therapies in multiple sclerosis by Gasperi, Christiane, Stüve, Olaf, Hemmer, Bernhard

“…Multiple sclerosis (MS) is a chronic inflammatory neurological disease of the CNS that goes along with demyelination and neurodegeneration. It is probably…”
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Ultrasound-detected inflammation is more common in clinically manifest hand osteoarthritis than in painless bony enlarged finger joints: subanalysis of the population-based Bruneck study by Gasperi, Nina, Schreiber, Nikolaus, Bosch, Philipp, Adinolfi, Antonella, Kleyer, Arnd, Hagen, Melanie, Gasperi, Christiane, Weger, Martin, Kiechl, Stefan, Willeit, Johann, Schett, Georg, Iagnocco, Annamaria, Gasperi, Arno, Mayr, Agnes, Dejaco, Christian

“…Purpose: The aim of this article is to examine the extent of structural and inflammatory lesions by ultrasound in elderly subjects with hand osteoarthritis…”
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Lesion location across diagnostic regions in multiple sclerosis by Pongratz, Viola, Bussas, Matthias, Schmidt, Paul, Grahl, Sophia, Gasperi, Christiane, El Husseini, Malek, Harabacz, Laura, Pineker, Viktor, Sepp, Dominik, Grundl, Lioba, Wiestler, Benedikt, Kirschke, Jan, Zimmer, Claus, Berthele, Achim, Hemmer, Bernhard, Mühlau, Mark

“…Lesions in the periventricular, (juxta)cortical, and infratentorial region, as visible on brain MRI, are part of the diagnostic criteria for Multiple sclerosis…”
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Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation by Andlauer, Till F M, Buck, Dorothea, Antony, Gisela, Bayas, Antonios, Bechmann, Lukas, Berthele, Achim, Chan, Andrew, Gasperi, Christiane, Gold, Ralf, Graetz, Christiane, Haas, Jürgen, Hecker, Michael, Infante-Duarte, Carmen, Knop, Matthias, Kümpfel, Tania, Limmroth, Volker, Linker, Ralf A, Loleit, Verena, Luessi, Felix, Meuth, Sven G, Mühlau, Mark, Nischwitz, Sandra, Paul, Friedemann, Pütz, Michael, Ruck, Tobias, Salmen, Anke, Stangel, Martin, Stellmann, Jan-Patrick, Stürner, Klarissa H, Tackenberg, Björn, Then Bergh, Florian, Tumani, Hayrettin, Warnke, Clemens, Weber, Frank, Wiendl, Heinz, Wildemann, Brigitte, Zettl, Uwe K, Ziemann, Ulf, Zipp, Frauke, Arloth, Janine, Weber, Peter, Radivojkov-Blagojevic, Milena, Scheinhardt, Markus O, Dankowski, Theresa, Bettecken, Thomas, Lichtner, Peter, Czamara, Darina, Carrillo-Roa, Tania, Binder, Elisabeth B, Berger, Klaus, Bertram, Lars, Franke, Andre, Gieger, Christian, Herms, Stefan, Homuth, Georg, Ising, Marcus, Jöckel, Karl-Heinz, Kacprowski, Tim, Kloiber, Stefan, Laudes, Matthias, Lieb, Wolfgang, Lill, Christina M, Lucae, Susanne, Meitinger, Thomas, Moebus, Susanne, Müller-Nurasyid, Martina, Nöthen, Markus M, Petersmann, Astrid, Rawal, Rajesh, Schminke, Ulf, Strauch, Konstantin, Völzke, Henry, Waldenberger, Melanie, Wellmann, Jürgen, Porcu, Eleonora, Mulas, Antonella, Pitzalis, Maristella, Sidore, Carlo, Zara, Ilenia, Cucca, Francesco, Zoledziewska, Magdalena, Ziegler, Andreas, Hemmer, Bernhard, Müller-Myhsok, Bertram

“…We conducted a genome-wide association study (GWAS) on multiple sclerosis (MS) susceptibility in German cohorts with 4888 cases and 10,395 controls. In…”
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DNA methylation as a mediator of HLA-DRB115:01 and a protective variant in multiple sclerosis by Kular, Lara, Liu, Yun, Ruhrmann, Sabrina, Zheleznyakova, Galina, Marabita, Francesco, Gomez-Cabrero, David, James, Tojo, Ewing, Ewoud, Lindén, Magdalena, Górnikiewicz, Bartosz, Aeinehband, Shahin, Stridh, Pernilla, Link, Jenny, Andlauer, Till F. M., Gasperi, Christiane, Wiendl, Heinz, Zipp, Frauke, Gold, Ralf, Tackenberg, Björn, Weber, Frank, Hemmer, Bernhard, Strauch, Konstantin, Heilmann-Heimbach, Stefanie, Rawal, Rajesh, Schminke, Ulf, Schmidt, Carsten O., Kacprowski, Tim, Franke, Andre, Laudes, Matthias, Dilthey, Alexander T., Celius, Elisabeth G., Søndergaard, Helle B., Tegnér, Jesper, Harbo, Hanne F., Oturai, Annette B., Olafsson, Sigurgeir, Eggertsson, Hannes P., Halldorsson, Bjarni V., Hjaltason, Haukur, Olafsson, Elias, Jonsdottir, Ingileif, Stefansson, Kari, Olsson, Tomas, Piehl, Fredrik, Ekström, Tomas J., Kockum, Ingrid, Feinberg, Andrew P., Jagodic, Maja

“…The human leukocyte antigen (HLA) haplotype DRB1*15 : 01 is the major risk factor for multiple sclerosis (MS). Here, we find that DRB1*15 : 01 is…”
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Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic TH17 cells by Heink, Sylvia, Yogev, Nir, Garbers, Christoph, Herwerth, Marina, Aly, Lilian, Gasperi, Christiane, Husterer, Veronika, Croxford, Andrew L, Möller-Hackbarth, Katja, Bartsch, Harald S, Sotlar, Karl, Krebs, Stefan, Regen, Tommy, Blum, Helmut, Hemmer, Bernhard, Misgeld, Thomas, Wunderlich, Thomas F, Hidalgo, Juan, Oukka, Mohamed, Rose-John, Stefan, Schmidt-Supprian, Marc, Waisman, Ari, Korn, Thomas

“…Korn and colleagues report that Sirpα + dendritic cells trans-present the cytokine IL-6 to T cells through a process that requires its receptor IL-6Rα bound to…”
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A large case-control study on vaccination as risk factor for multiple sclerosis by Hapfelmeier, Alexander, Gasperi, Christiane, Donnachie, Ewan, Hemmer, Bernhard

“…OBJECTIVETo investigate the hypothesis that vaccination is a risk factor for multiple sclerosis (MS) by use of German ambulatory claims data in a case-control…”
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Vaccination as a risk factor for pediatric multiple sclerosis: Insights from a retrospective case–control study by Darvishi, Sonia, Donnachie, Ewan, Gasperi, Christiane, Hapfelmeier, Alexander, Hemmer, Bernhard

“…This study evaluated the association between pediatric multiple sclerosis and vaccinations within 5 years before diagnosis using German ambulatory claims data…”
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Systematic Assessment of Medical Diagnoses Preceding the First Diagnosis of Multiple Sclerosis by Gasperi, Christiane, Hapfelmeier, Alexander, Daltrozzo, Tanja, Schneider, Antonius, Donnachie, Ewan, Hemmer, Bernhard

“…To explore the occurrence of diseases and symptoms in the 5 years before diagnosis in patients with multiple sclerosis (MS) in a case-control study. Using…”
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Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic T H 17 cells by Heink, Sylvia, Yogev, Nir, Garbers, Christoph, Herwerth, Marina, Aly, Lilian, Gasperi, Christiane, Husterer, Veronika, Croxford, Andrew L, Möller-Hackbarth, Katja, Bartsch, Harald S, Sotlar, Karl, Krebs, Stefan, Regen, Tommy, Blum, Helmut, Hemmer, Bernhard, Misgeld, Thomas, Wunderlich, Thomas F, Hidalgo, Juan, Oukka, Mohamed, Rose-John, Stefan, Schmidt-Supprian, Marc, Waisman, Ari, Korn, Thomas

“…The cellular sources of interleukin 6 (IL-6) that are relevant for differentiation of the T 17 subset of helper T cells remain unclear. Here we used a novel…”
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Anti-agrin autoantibodies in myasthenia gravis by Gasperi, Christiane, Melms, Arthur, Schoser, Benedikt, Zhang, Yina, Meltoranta, Julia, Risson, Valerie, Schaeffer, Laurent, Schalke, Bertold, Kröger, Stephan

“…OBJECTIVE:Because the extracellular matrix protein agrin is essential for neuromuscular junction formation and maintenance, we tested the hypothesis that…”
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Systematic Assessment of Medical Diagnoses Preceding the First Diagnosis of Multiple Sclerosis by Gasperi, Christiane, Hapfelmeier, Alexander, Daltrozzo, Tanja, Schneider, Antonius, Donnachie, Ewan, Hemmer, Bernhard

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