Search Results - "Gasparo, Marc"

Enkephalinase activity is modified and correlates with fatty acids in frontal cortex depending on fish, olive or coconut oil used in the diet by Segarra, Ana B., Prieto, Isabel, Martinez-Canamero, Magdalena, Ruiz-Sanz, Jose-Ignacio, Ruiz-Larrea, M. Begona, De Gasparo, Marc, Banegas, Inmaculada, Zorad, Stefan, Ramirez-Sanchez, Manuel

“…Enkephalins are neuropeptides involved in functions such as pain modulation and/ or cognitive processes. It has been reported that dietary fat modifies…”
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Divergent profile between hypothalamic and plasmatic aminopeptidase activities in WKY and SHR. Influence of beta-adrenergic blockade by Prieto, Isabel, Segarra, Ana B., de Gasparo, Marc, Martínez-Cañamero, Magdalena, Ramírez-Sánchez, Manuel

“…Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR) differ in their renin-angiotensin system function and sympathetic tone. The metabolism of…”
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Interaction between Angiotensinase Activities in Pituitary and Adrenal Glands of Wistar-Kyoto and Spontaneously Hypertensive Rats under Hypotensive or Hypertensive Treatments by Segarra, Ana B, Prieto, Isabel, Banegas, Inmaculada, Martínez-Cañamero, Magdalena, Villarejo, Ana B, Domínguez-Vías, Germán, de Gasparo, Marc, Ramírez-Sánchez, Manuel

“…In the present study, we analyzed the activity of several aminopeptidases (angiotensinases) involved in the metabolism of various angiotensin peptides, in…”
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Role of central and peripheral aminopeptidase activities in the control of blood pressure: a working hypothesis by Ramírez, Manuel, Prieto, Isabel, Alba, Francisco, Vives, Francisco, Banegas, Inmaculada, de Gasparo, Marc

“…Although there is a large body of knowledge on protein synthesis, the available data on protein catabolism, although quite substantial, are still inadequate…”
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Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage by Gelosa, Paolo, Pignieri, Alice, Fändriks, Lars, de Gasparo, Marc, Hallberg, Anders, Banfi, Cristina, Castiglioni, Laura, Turolo, Lucia, Guerrini, Uliano, Tremoli, Elena, Sironi, Luigi

“…BACKGROUND AND AIMAngiotensin II acts through two major receptorsAT1-R and AT2-R. It is known that the stimulation of AT1-R mediates vasoconstriction, cell…”
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Combination of the dipeptidyl peptidase IV inhibitor LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] with the angiotensin II type 1 receptor antagonist valsartan [N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl]-L-valine] enhances pancreatic islet morphology and function in a mouse model of type 2 diabetes by Cheng, Qianni, Law, Pui Ki, de Gasparo, Marc, Leung, Po Sing

“…LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] is an inhibitor of dipeptidyl peptidase IV that delays the degradation of glucagon-like…”
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Brain Asymmetry: Towards an Asymmetrical Neurovisceral Integration by Ramírez-Sánchez, Manuel, Prieto, Isabel, Segarra, Ana Belén, Banegas, Inmaculada, Martínez-Cañamero, Magdalena, Domínguez-Vías, Germán, de Gasparo, Marc

“…Despite the ancestral evidence of an asymmetry in motor predominance, going through the inspiring discoveries of Broca and Wernicke on the localization of…”
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The Brain-Heart Connection: Frontal Cortex and Left Ventricle Angiotensinase Activities in Control and Captopril-Treated Hypertensive Rats-A Bilateral Study by Segarra, Ana B., Prieto, Isabel, Banegas, Inmaculada, Villarejo, Ana B., Wangensteen, Rosemary, de Gasparo, Marc, Vives, Francisco, Ramírez-Sánchez, Manuel

“…The model of neurovisceral integration suggests that the frontal cortex (FC) and the cardiovascular function are reciprocally and asymmetrically connected. We…”
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Brain RAS: Hypertension and Beyond by Baltatu, Ovidiu C., Speth, Robert C., Gasparo, Marc de, Vanderheyden, Patrick

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Blood Pressure Correlates Asymmetrically with Neuropeptidase Activities of the Left and Right Frontal Cortices by Segarra, Ana Belén, Prieto, Isabel, Banegas, Inmaculada, Martínez-Cañamero, Magdalena, de Gasparo, Marc, Ramírez-Sánchez, Manuel

“…It was suggested that the brain-heart connection is asymmetrically organized. However, evidence connecting neurochemical factors from each brain hemisphere…”
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Thyroid Disorders Change the Pattern of Response of Angiotensinase Activities in the Hypothalamus-Pituitary-Adrenal Axis of Male Rats by Segarra, Ana B, Prieto, Isabel, Martínez-Cañamero, Magdalena, de Gasparo, Marc, Luna, Juan de Dios, Ramírez-Sánchez, Manuel

“…Thyroid disorders affect the hypothalamic-pituitary-adrenal axis with important consequences on the cardiovascular function in which the renin-angiotensin…”
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Asymmetric Interaction of Neuropeptidase Activities between Cortico-Limbic Structures, Plasma and Cardiovascular Function after Unilateral Dopamine Depletions of the Nigrostriatal System by Banegas, Inmaculada, Prieto, Isabel, Segarra, Ana Belén, Vives, Francisco, Martínez-Cañamero, Magdalena, Durán, Raquel, Luna, Juan de Dios, de Gasparo, Marc, Domínguez-Vías, Germán, Ramírez-Sánchez, Manuel

“…In emotional processing, dopamine (DA) plays an essential role, and its deterioration involves important consequences. Under physiological conditions, dopamine…”
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Pharmacological profile of valsartan: a potent, orally active, nonpeptide antagonist of the angiotensin II AT1‐receptor subtype by Criscione, Leoluca, Gasparo, Marc, Bühlmayer, Peter, Whitebread, Steven, Ramjoué, Hans‐peter R., Wood, Jeanette

“…1 The pharmacological profile of valsartan, (S)‐N‐valeryl‐N‐{[2′‐(1H‐tetrazol‐5‐yl)biphenyl‐4‐yl]‐methyl}‐valine, a potent, highly selective, and orally active…”
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The Type of Fat in the Diet Influences the Behavior and the Relationship Between Cystinyl and Alanyl Aminopeptidase Activities in Frontal Cortex, Liver, and Plasma by Segarra, Ana Belén, Prieto, Isabel, Banegas, Inmaculada, Martínez-Cañamero, Magdalena, de Gasparo, Marc, Vanderheyden, Patrick, Zorad, Stefan, Ramírez-Sánchez, Manuel

“…Insulin-regulated aminopeptidase (IRAP, cystinyl aminopeptidase, CysAP) and aminopeptidase M (alanyl aminopeptidase, AlaAP) are closely related enzymes…”
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Involvement of the pancreatic renin-angiotensin system in insulin resistance and the metabolic syndrome by Leung, Po Sing, de Gasparo, Marc

“…The cardiometabolic syndrome consists of several major components: hypertension, hyperinsulinemia, hyperlipidemia, and hyperglycemia. Central to this syndrome…”
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Asymmetrical effect of captopril on the angiotensinase activity in frontal cortex and plasma of the spontaneously hypertensive rats: Expanding the model of neuroendocrine integration by Segarra, Ana Belén, Prieto, Isabel, Banegas, Inmaculada, Villarejo, Ana Belén, Wangensteen, Rosemary, de Gasparo, Marc, Vives, Francisco, Ramírez-Sánchez, Manuel

“…► Captopril modifies the bilateral distribution of aminopeptidases in frontal cortex. ► There is a lateralized correlation between frontal cortex and plasma in…”
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Frontiers in diabetic research by Leung, Po Sing, Hayek, Alberto, Gasparo, Marc de

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Distribution of type-1 and type-2 angiotensin receptors in the normal human lung and in lungs from patients with chronic obstructive pulmonary disease by Bullock, G R, Steyaert, I, Bilbe, G, Carey, R M, Kips, J, De Paepe, B, Pauwels, R, Praet, M, Siragy, H M, de Gasparo, M

“…This study was designed to examine the cellular distribution of the angiotensin II type-1 (AT1) and type-2 (AT2) receptors in the normal human and pathological…”
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Angiotensin Type 2 Receptor Mediates Valsartan-Induced Hypotension in Conscious Rats by Siragy, Helmy M, de Gasparo, Marc, Carey, Robert M

“…Inhibition of the renin-angiotensin system is associated with vasodilation and reduction in blood pressure. We hypothesized that angiotensin type 1 (AT1)…”
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Angiotensin type 2 receptor antagonism confers renal protection in a rat model of progressive renal injury by CAO, Zemin, BONNET, Fabrice, CANDIDO, Riccardo, NESTEROFF, Stefan P, BURNS, Wendy C, KAWACHI, Hiroshi, SHIMIZU, Fujio, CAREY, Robert M, DE GASPARD, Marc, COOPER, Mark E

“…The role of the angiotensin type 2 (AT(2)) receptor in the pathogenesis of progressive renal injury has not been previously elucidated. The renal expression of…”
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