Search Results - "Gaspari, Flavio"
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Anti-Phospholipase A2 Receptor Antibody Titer Predicts Post-Rituximab Outcome of Membranous Nephropathy
Published in Journal of the American Society of Nephrology (01-10-2015)“…Rituximab induces nephrotic syndrome (NS) remission in two-thirds of patients with primary membranous nephropathy (MN), even after other treatments have…”
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2
Rituximab in Idiopathic Membranous Nephropathy
Published in Journal of the American Society of Nephrology (01-08-2012)“…Selective depletion of B cells with the mAb rituximab may benefit the autoimmune glomerular disease idiopathic membranous nephropathy (IMN). Here, we describe…”
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3
Glomerular Hyperfiltration and Renal Disease Progression in Type 2 Diabetes
Published in Diabetes care (01-10-2012)“…To describe the prevalence and determinants of hyperfiltration (glomerular filtration rate [GFR] ≥120 mL/min/1.73 m(2)), GFR decline, and nephropathy onset or…”
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Effect of longacting somatostatin analogue on kidney and cyst growth in autosomal dominant polycystic kidney disease (ALADIN): a randomised, placebo-controlled, multicentre trial
Published in The Lancet (British edition) (02-11-2013)“…Summary Background Autosomal dominant polycystic kidney disease slowly progresses to end-stage renal disease and has no effective therapy. A pilot study…”
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5
GFR measurement in patients with CKD: Performance and feasibility of simplified iohexol plasma clearance techniques
Published in PloS one (17-07-2024)“…Implementing shortened one-compartment iohexol plasma clearance models for GFR measurement is crucial since the gold standard inulin renal clearance technique…”
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6
Octreotide-LAR in later-stage autosomal dominant polycystic kidney disease (ALADIN 2): A randomized, double-blind, placebo-controlled, multicenter trial
Published in PLoS medicine (05-04-2019)“…Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent genetically determined renal disease. In affected patients, renal function may…”
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Iohexol plasma clearance simplified by Dried Blood Spot (DBS) sampling to measure renal function in conscious mice
Published in Scientific reports (25-02-2021)“…There is no simple method to measure glomerular filtration rate (GFR) in mice, which limits the use of mice in models of renal diseases. We aimed at…”
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8
Renal expression of FGF23 in progressive renal disease of diabetes and the effect of ACE inhibitor
Published in PloS one (14-08-2013)“…Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone mainly produced by bone that acts in the kidney through FGF receptors and Klotho. Here we…”
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Long-Term Clinical and Immunological Profile of Kidney Transplant Patients Given Mesenchymal Stromal Cell Immunotherapy
Published in Frontiers in immunology (14-06-2018)“…We report here the long-term clinical and immunological results of four living-donor kidney transplant patients given autologous bone marrow-derived…”
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10
Impact and consequences of the error of estimated GFR in patients with heart failure
Published in Scientific reports (28-10-2024)“…Heart failure is a highly prevalent disease, which courses with frequent readmissions, mainly by Acute Heart Failure (AHF). Reduced renal function is…”
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Mycophenolate mofetil versus azathioprine in kidney transplant recipients on steroid-free, low-dose cyclosporine immunosuppression (ATHENA): A pragmatic randomized trial
Published in PLoS medicine (01-06-2021)“…Background We compared protection of mycophenolate mofetil (MMF) and azathioprine (AZA) against acute cellular rejection (ACR) and chronic allograft…”
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12
Glomerular resistances predict long-term GFR decline in type 2 diabetic patients without overt nephropathy: a longitudinal subgroup analysis of the DEMAND trial
Published in Acta diabetologica (01-03-2022)“…Aims Investigating whether and to what extent changes in glomerular hemodynamic parameters, beyond glomerular hyperfiltration, could predict glomerular…”
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13
Preventing Microalbuminuria in Type 2 Diabetes
Published in The New England journal of medicine (04-11-2004)“…In a multicenter, double-blind, placebo-controlled, randomized study, subjects with type 2 diabetes mellitus and hypertension but normal urinary albumin levels…”
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14
Sirolimus Therapy to Halt the Progression of ADPKD
Published in Journal of the American Society of Nephrology (01-06-2010)“…Activation of mammalian target of rapamycin (mTOR) pathways may contribute to uncontrolled cell proliferation and secondary cyst growth in patients with…”
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15
Preventing microalbuminuria with benazepril, valsartan, and benazepril–valsartan combination therapy in diabetic patients with high-normal albuminuria: A prospective, randomized, open-label, blinded endpoint (PROBE) study
Published in PLoS medicine (01-07-2021)“…Background Angiotensin converting enzyme (ACE) inhibitors and angiotensin receptor blockers (ARBs) prevent microalbuminuria in normoalbuminuric type 2 diabetic…”
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Measured and Estimated Glomerular Filtration Rate to Evaluate Rapid Progression and Changes over Time in Autosomal Polycystic Kidney Disease: Potential Impact on Therapeutic Decision-Making
Published in International journal of molecular sciences (01-05-2024)“…Autosomal polycystic kidney disease (ADPKD) is the most common genetic form of kidney failure, reflecting unmet needs in management. Prescription of the only…”
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17
Kidney transplant tolerance associated with remote autologous mesenchymal stromal cell administration
Published in Stem cells translational medicine (01-04-2020)“…Here we report the case of successful immune tolerance induction in a living‐donor kidney transplant recipient remotely treated with autologous bone…”
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18
Measuring and estimating GFR and treatment effect in ADPKD patients: results and implications of a longitudinal cohort study
Published in PloS one (28-02-2012)“…Trials failed to demonstrate protective effects of investigational treatments on glomerular filtration rate (GFR) reduction in Autosomal Dominant Polycystic…”
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19
A Simple Method to Measure Renal Function in Swine by the Plasma Clearance of Iohexol
Published in International journal of molecular sciences (12-01-2018)“…There is no simple method to measure glomerular filtration rate (GFR) in swine, an established model for studying renal disease. We developed a protocol to…”
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Renal function and requirement for dialysis in chronic nephropathy patients on long-term ramipril: REIN follow-up trial
Published in The Lancet (British edition) (17-10-1998)“…The Ramipril Efficacy In Nephropathy (REIN) study found that in patients with chronic nephropathies and proteinuria of 3 g or more per 24 h, ramipril safely…”
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