Search Results - "Gaspar, Pablo"
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Metabolic syndrome and obesity among users of second generation antipsychotics: A global challenge for modern psychopharmacology
Published in Pharmacological research (01-11-2015)“…[Display omitted] Second generation antipsychotics (SGAs), such as clozapine, olanzapine, risperidone and quetiapine, are among the most effective therapies to…”
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BDNF as a Biomarker of Cognition in Schizophrenia/Psychosis: An Updated Review
Published in Frontiers in psychiatry (16-06-2021)“…Brain Derived Neurotrophic Factor (BDNF) has been linked to cognitive symptoms of schizophrenia, which has been documented in previous reviews by several…”
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Impaired Motion Processing in Schizophrenia and the Attenuated Psychosis Syndrome: Etiological and Clinical Implications
Published in The American journal of psychiatry (01-12-2018)“…Objective:The ability to perceive the motion of biological objects, such as faces, is a critical component of daily function and correlates with the ability to…”
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Cognitive impairment in agricultural workers and nearby residents exposed to pesticides in the Coquimbo Region of Chile
Published in Neurotoxicology and teratology (01-07-2017)“…Abstract Chronic exposure to organophosphate pesticides is a worldwide public health concern associated with several psychiatric disorders and dementia. Most…”
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Lifetime prevalence of psychotic-like experiences and associated factors in Chile
Published in Social Psychiatry and Psychiatric Epidemiology (27-07-2024)“…Psychotic-like experiences (PLEs), which include hallucinations and delusional experiences, are usually present in healthy populations, and their persistence,…”
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Fixational eye movements and their associated evoked potentials during natural vision are altered in schizophrenia
Published in Schizophrenia research. Cognition (01-12-2024)“…Visual exploration is abnormal in schizophrenia; however, few studies have investigated the physiological responses during selecting objectives in more…”
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Disrupted third visual pathway function in schizophrenia: Evidence from real and implied motion processing
Published in NeuroImage clinical (01-01-2024)“…•Examined processing of real and implied motion in Sz using naturalistic stimuli.•Neural activation elicited by both real and implied motion stimuli is reduced…”
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Molecular mechanisms underlying glutamatergic dysfunction in schizophrenia: therapeutic implications
Published in Journal of neurochemistry (01-11-2009)“…Early models for the etiology of schizophrenia focused on dopamine neurotransmission because of the powerful anti-psychotic action of dopamine antagonists…”
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Disease-Specific Contribution of Pulvinar Dysfunction to Impaired Emotion Recognition in Schizophrenia
Published in Frontiers in behavioral neuroscience (14-02-2022)“…One important aspect for managing social interactions is the ability to perceive and respond to facial expressions rapidly and accurately. This ability is…”
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Montreal Cognitive Assessment (MoCA) as a screening tool for cognitive impairment in early stages of psychosis
Published in Schizophrenia research. Cognition (01-06-2024)“…Cognitive alterations have been reported in early stages of psychosis including people with First Episode Psychosis (FEP), Clinical High-Risk Mental State…”
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Automatic language analysis identifies and predicts schizophrenia in first-episode of psychosis
Published in NPJ schizophrenia (01-06-2022)“…Automated language analysis of speech has been shown to distinguish healthy control (HC) vs chronic schizophrenia (SZ) groups, yet the predictive power on…”
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Shifting the focus toward rare variants in schizophrenia to close the gap from genotype to phenotype
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01-10-2017)“…Schizophrenia (SZ) is a disorder with a high heritability and a complex architecture. Several dozen genetic variants have been identified as risk factors…”
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From Molecules to the Clinic: Linking Schizophrenia and Metabolic Syndrome through Sphingolipids Metabolism
Published in Frontiers in neuroscience (08-11-2016)“…Metabolic syndrome (MS) is a prevalent and severe comorbidity observed in schizophrenia (SZ). The exact nature of this association is controversial and very…”
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The effect of a mindfulness-based intervention in cognitive functions and psychological well-being applied as an early intervention in schizophrenia and high-risk mental state in a Chilean sample: study protocol for a randomized controlled trial
Published in Current controlled trials in cardiovascular medicine (25-05-2017)“…According to the projections of the World Health Organization, 15% of all disabilities will be associated with mental illnesses by 2020. One of the mental…”
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Neural oscillatory deficits in schizophrenia predict behavioral and neurocognitive impairments
Published in Frontiers in human neuroscience (01-07-2015)“…Paying attention to visual stimuli is typically accompanied by event-related desynchronizations (ERD) of ongoing alpha (7-14 Hz) activity in visual cortex. The…”
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RELATION BETWEEN COGNITIVE IMPAIRMENTS IN ALZHEIMER DISEASE AND DEPRESSION
Published in IBRO neuroscience reports (01-10-2023)Get full text
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Imitative inhibitory control is associated with psychotic experiences in a sample from the general population
Published in Frontiers in psychiatry (11-11-2024)“…Psychotic experiences (PE) are prevalent and associated with several negative mental health outcomes in both clinical and general population, particularly in…”
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P300 amplitude is insensitive to working memory load in schizophrenia
Published in BMC psychiatry (15-02-2011)“…Working memory (WM) tasks usually elicit a P300 ERP component, whose amplitude decreases with increasing WM load. So far, this effect has not been studied in…”
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Early psychosis detection program in Chile: A first step for the South American challenge in psychosis research
Published in Early intervention in psychiatry (01-04-2019)“…Aim Early detection and intervention (EDI) is a main challenge in psychosis research. The Chilean schizophrenia (SZ) national program has universal support and…”
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