Search Results - "Gaspar, Maria Manuela"

Liposomal Delivery of Saquinavir to Macrophages Overcomes Cathepsin Blockade by Mycobacterium tuberculosis and Helps Control the Phagosomal Replicative Niches by Pires, David, Mandal, Manoj, Pinho, Jacinta, Catalão, Maria João, Almeida, António José, Azevedo-Pereira, José Miguel, Gaspar, Maria Manuela, Anes, Elsa

“…is able to establish a chronic colonization of lung macrophages in a controlled replication manner, giving rise to a so-called latent infection. Conversely,…”
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Nanoformulation of seaweed eisenia bicyclis in albumin nanoparticles targeting cardiovascular diseases: In vitro and in vivo evaluation by Pinto, Sofia, de Jesus Guilherme Gaspar, Maria Manuela, Ascensão, Lia, Faisca, Pedro, Beco Pinto Reis, Ana Catarina, Pacheco, Rita

“…Natural products, especially those derived from seaweeds, are starting to be seen as effective against various diseases, such as cardiovascular diseases…”
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Liposomal Delivery of Newly Identified Prophage Lysins in a Pseudomonas aeruginosa Model by Morais, Diana, Tanoeiro, Luís, Marques, Andreia, Gonçalves, Tiago, Duarte, Aida, Matos, António, Vital, Joana, Cruz, Maria, Carvalheiro, Manuela, Anes, Elsa, Vítor, Jorge, Gaspar, Maria, Vale, Filipa

“…Pseudomonas aeruginosa is a Gram-negative opportunistic bacterium that presents resistance to several antibiotics, thus, representing a major threat to human…”
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The Role of Rosmarinic Acid on the Bioproduction of Gold Nanoparticles as Part of a Photothermal Approach for Breast Cancer Treatment by Ferreira-Gonçalves, Tânia, Gaspar, Maria Manuela, Coelho, João M P, Marques, Vanda, Viana, Ana S, Ascensão, Lia, Carvalho, Lina, Rodrigues, Cecília M P, Ferreira, Hugo Alexandre, Ferreira, David, Reis, Catarina Pinto

“…Breast cancer is a high-burden malignancy for society, whose impact boosts a continuous search for novel diagnostic and therapeutic tools. Among the recent…”
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Liposomes as Antibiotic Delivery Systems: A Promising Nanotechnological Strategy against Antimicrobial Resistance by Ferreira, Magda, Ogren, Maria, Dias, Joana N R, Silva, Marta, Gil, Solange, Tavares, Luís, Aires-da-Silva, Frederico, Gaspar, Maria Manuela, Aguiar, Sandra Isabel

“…Antimicrobial drugs are key tools to prevent and treat bacterial infections. Despite the early success of antibiotics, the current treatment of bacterial…”
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Current Trends in Cancer Nanotheranostics: Metallic, Polymeric, and Lipid-Based Systems by Silva, Catarina Oliveira, Pinho, Jacinta Oliveira, Lopes, Joana Margarida, Almeida, António J, Gaspar, Maria Manuela, Reis, Catarina

“…Theranostics has emerged in recent years to provide an efficient and safer alternative in cancer management. This review presents an updated description of…”
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Role of ionic liquids in ibuprofen-based eutectic systems: Aqueous solubility, permeability, human cytotoxicity, hemolytic activity and anti-inflammatory activity by Bastos, Joana C., Manuela Gaspar, Maria, Pereiro, Ana B., Araújo, João M.M.

“…[Display omitted] •Twelve pharmaceutically active eutectics based on ibuprofen conjugated with imidazolium-based ILs or cholinium salt at different molar ratio…”
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Recent advances in ionic liquids and nanotechnology for drug delivery by Amaral, Mariana, Pereiro, Ana B, Gaspar, Maria Manuela, Reis, Catarina Pinto

“…In drug discovery and drug development, it is estimated that around 40% of commercialized and 90% of under-study drugs have inadequate pharmaceutical…”
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Antimicrobial activity of prophage endolysins against critical Enterobacteriaceae antibiotic-resistant bacteria by Gonçalves, Tiago, Marques, Andreia T., Manageiro, Vera, Tanoeiro, Luis, Vital, Joana S., Duarte, Aida, Vítor, Jorge M.B., Caniça, Manuela, Gaspar, Maria Manuela, Vale, Filipa F.

“…[Display omitted] Enterobacteriaceae species are part of the 2017 World Health Organization antibiotic-resistant priority pathogens list for development of…”
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Rifabutin: a repurposed antibiotic with high potential against planktonic and biofilm staphylococcal clinical isolates by Ferreira, Magda, Pinto, Margarida, Aires-da-Silva, Frederico, Bettencourt, Ana, Gaspar, Maria Manuela, Aguiar, Sandra Isabel

“…poses a significant threat as an opportunistic pathogen in humans, and animal medicine, particularly in the context of hospital-acquired infections (HAIs)…”
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The Aquaporin-3-Inhibiting Potential of Polyoxotungstates by Pimpão, Catarina, da Silva, Inês V, Mósca, Andreia F, Pinho, Jacinta O, Gaspar, Maria Manuela, Gumerova, Nadiia I, Rompel, Annette, Aureliano, Manuel, Soveral, Graça

“…Polyoxometalates (POMs) are of increasing interest due to their proven anticancer activities. Aquaporins (AQPs) were found to be overexpressed in tumors…”
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Emergent Nanotechnological Strategies for Systemic Chemotherapy against Melanoma by Oliveira Pinho, Jacinta, Matias, Mariana, Gaspar, Maria Manuela

“…Melanoma is an aggressive form of skin cancer, being one of the deadliest cancers in the world. The current treatment options involve surgery, radiotherapy,…”
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Advancing Medicine with Lipid-Based Nanosystems-The Successful Case of Liposomes by Luiz, Hugo, Oliveira Pinho, Jacinta, Gaspar, Maria Manuela

“…Nanomedicine, a promising area of medicine, employs nanosized tools for the diagnosis, prevention, and treatment of disease. Particularly, liposomes,…”
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Liposomal Formulations of a New Zinc(II) Complex Exhibiting High Therapeutic Potential in a Murine Colon Cancer Model by Ribeiro, Nádia, Albino, Melissa, Ferreira, Andreia, Escrevente, Cristina, Barral, Duarte C, Pessoa, João Costa, Reis, Catarina Pinto, Gaspar, Maria Manuela, Correia, Isabel

“…Colorectal cancer is the second leading cause of cancer-related mortality. Many current therapies rely on chemotherapeutic agents with poor specificity for…”
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A Step Forward for the Treatment of Localized Prostate Cancer Using Gold Nanoparticles Combined with Laser Irradiation by Pinho, Sara, Ferreira-Gonçalves, Tânia, Lopes, Joana, Amaral, Mariana Neves, Viana, Ana S, Coelho, João M P, Gaspar, Maria Manuela, Reis, Catarina Pinto

“…Prostate cancer (PCA) is the second most common cancer diagnosis in men and the fifth leading cause of death worldwide. The conventional treatments available…”
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A Comprehensive Updated Review on Magnetic Nanoparticles in Diagnostics by Farinha, Pedro, Coelho, João M P, Reis, Catarina Pinto, Gaspar, Maria Manuela

“…Magnetic nanoparticles (MNPs) have been studied for diagnostic purposes for decades. Their high surface-to-volume ratio, dispersibility, ability to interact…”
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How to Treat Melanoma? The Current Status of Innovative Nanotechnological Strategies and the Role of Minimally Invasive Approaches like PTT and PDT by Lopes, Joana, Rodrigues, Cecília M. P, Gaspar, Maria Manuela, Reis, Catarina Pinto

“…Melanoma is the most aggressive type of skin cancer, the incidence and mortality of which are increasing worldwide. Its extensive degree of heterogeneity has…”
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Nanoformulations of a potent copper-based aquaporin inhibitor with cytotoxic effect against cancer cells by Nave, Mariana, Castro, Rui E, Rodrigues, Cecília MP, Casini, Angela, Soveral, Graça, Gaspar, Maria Manuela

“…Development of liposomal formulations of Cuphen, a potent copper-based aquaporin inhibitor with therapeutic potential against melanoma and colon cancer. Cuphen…”
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Experimental Murine Models for Colorectal Cancer Research by Neto, Íris, Rocha, João, Gaspar, Maria Manuela, Reis, Catarina P

“…Colorectal cancer (CRC) is the third most prevalent malignancy worldwide and in both sexes. Numerous animal models for CRC have been established to study its…”
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The Challenging Melanoma Landscape: From Early Drug Discovery to Clinical Approval by Matias, Mariana, Pinho, Jacinta O, Penetra, Maria João, Campos, Gonçalo, Reis, Catarina Pinto, Gaspar, Maria Manuela

“…Melanoma is recognized as the most dangerous type of skin cancer, with high mortality and resistance to currently used treatments. To overcome the limitations…”
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