Search Results - "Gasonoo, Makafui"

Superelectrophilic carbocations: preparation and reactions of a substrate with six ionizable groups by Kennedy, Sean H, Gasonoo, Makafui, Klumpp, Douglas A

“…A substrate has been prepared having two triarylmethanol centers and four pyridine-type substituent groups. Upon ionization in the Brønsted superacid CF SO H,…”
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Identification of potent and orally efficacious phosphodiesterase inhibitors in Cryptosporidium parvum-infected immunocompromised male mice by Ajiboye, Jubilee, Teixeira, José E., Gasonoo, Makafui, Mattice, Ethan B., Korwin-Mihavics, Bethany, Miller, Peter, Cameron, Alexandra C., Stebbins, Erin, Campbell, Scott D., Griggs, David W., Spangenberg, Thomas, Meyers, Marvin J., Huston, Christopher D.

“…Cryptosporidium parvum and C. hominis are parasites that cause life-threatening diarrhea in children and immunocompromised people. There is only one approved…”
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Superacid-promoted synthesis of polychlorinated dibenzofurans by Qarah, Ahmad, Gasonoo, Makafui, Do, Dat, Klumpp, Douglas A.

“…[Display omitted] •A one step procedure has been developed for the synthesis of polychlorinated dibenzofurans.•The chemistry involves a superacid-promoted…”
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Synthesis of Heterocycle-Containing 9,9-Diarylfluorenes Using Superelectrophiles by Gasonoo, Makafui, Sumita, Akinari, Boblak, Kenneth N, Giuffre, Kristen, Ohwada, Tomohiko, Klumpp, Douglas A

“…A superacid-promoted method for the synthesis of 9,9-diarylfluorenes is described. The chemistry involves cyclizations and arylations with biphenyl-substituted…”
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Synthesis of functionalized 2-oxindoles by Friedel–Crafts reactions by Gasonoo, Makafui, Klumpp, Douglas A.

“…[Display omitted] A series of acetonyl-substituted 3-hydroxy-2-oxindoles have been prepared and reacted with arenes in superacid promoted Friedel–Crafts…”
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Regioselective α‑Amination of Ethers Using Stable N‑Chloroimides and Lithium tert-Butoxide by Gasonoo, Makafui, Thom, Zachary W, Laulhé, Sébastien

“…Herein we describe a metal-free regioselective α-amination of ethers mediated by N-chloroimides in ethereal solvents in the presence of lithium tert-butoxide…”
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Efficient Inhibition of Hepatitis B Virus (HBV) Replication and cccDNA Formation by HBV Ribonuclease H Inhibitors during Infection by Chauhan, Ranjit, Li, Qilan, Woodson, Molly E, Gasonoo, Makafui, Meyers, Marvin J, Tavis, John E

“…The hepatitis B virus (HBV) ribonuclease H (RNase H) is an attractive but unexploited drug target. Here, we addressed three limitations to the current state of…”
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Use of Charge‐Charge Repulsion to Enhance π‐Electron Delocalization into Anti‐Aromatic and Aromatic Systems by Sumita, Akinari, Gasonoo, Makafui, Boblak, Kenneth J., Ohwada, Tomohiko, Klumpp, Douglas A

“…A series of 9‐fluorenyl cations has been studied and it is shown that increasing charge on a heterocyclic substituent group enhances the anti‐aromatic…”
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Intramolecular Conjugate Additions with Heterocyclic Olefins by Boblak, Kenneth N, Gasonoo, Makafui, Zhang, Yiliang, Klumpp, Douglas A

“…The intramolecular reactions of olefinic N-heterocycles have been studied. In triflic acid-promoted reactions, conjugate addition is observed with pyrazine-,…”
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Use of Charge-Charge Repulsion to Enhance [pi]-Electron Delocalization into Anti-Aromatic and Aromatic Systems by Sumita, Akinari, Gasonoo, Makafui, Boblak, Kenneth J, Ohwada, Tomohiko, Klumpp, Douglas A

“…A series of 9-fluorenyl cations has been studied and it is shown that increasing charge on a heterocyclic substituent group enhances the anti-aromatic…”
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Tetra- and Pentacationic Electrophiles and Their Chemistry by Gasonoo, Makafui, Naredla, Rajasekhar Reddy, Nilsson Lill, Sten O, Klumpp, Douglas A

“…A tetracationic electrophile has been generated in superacid and shown to undergo an arylation reaction with benzene. A cyclization product is also obtained in…”
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Superacid Catalyzed Reactions: Generation of Reactive Intermediates and Their Chemistry by Gasonoo, Makafui

“…This dissertation describes the use of triflic acid as catalyst for generating reactive intermediates and studying their reactivities under varying reaction…”
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Synthesis of Imide and Amine Derivatives via Deoxyamination of Alcohols Using N‐Haloimides and Triphenylphosphine by Irving, Charles D., Floreancig, Jack T., Gasonoo, Makafui, Kelley, Alexandra S., Laulhé, Sébastien

“…A deoxyamination methodology of activated and unactivated alcohols is presented. The reaction is mediated by phosphonium intermediates generated in situ from…”
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