Search Results - "Gaskova, Dana"

Surface-functionalized PAN fiber membranes for the sensitive detection of airborne specific markers by Varvarovska, Leontyna, Sopko, Bruno, Gaskova, Dana, Bartl, Tomas, Amler, Evzen, Jarosikova, Tatana

“…PAN fibers are characterized by having a large surface-to-volume ratio and small pores, which are beneficial for applications in filtration and specific…”
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A novel method for assessment of local pH in periplasmic space and of cell surface potential in yeast by Plášek, Jaromír, Babuka, David, Gášková, Dana, Jančíková, Iva, Zahumenský, Jakub, Hoefer, Milan

“…Yeast cells exhibit a negative surface potential due to negative charges at the cell membrane surface. Consequently, local concentrations of cations at the…”
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Yeast Tok1p channel is a major contributor to membrane potential maintenance under chemical stress by Zahumenský, Jakub, Jančíková, Iva, Drietomská, Andrea, Švenkrtová, Andrea, Hlaváček, Otakar, Hendrych, Tomáš, Plášek, Jaromír, Sigler, Karel, Gášková, Dana

“…Tok1p is a highly specific yeast plasma membrane potassium channel with strong outward directionality. Its opening is induced by membrane depolarization…”
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Synergy between azoles and 1,4-dihydropyridine derivative as an option to control fungal infections by Ježíková, Zuzana, Pagáč, Tomáš, Pfeiferová, Barbora, Bujdáková, Helena, Dižová, Stanislava, Jančíková, Iva, Gášková, Dana, Olejníková, Petra

“…With emerging fungal infections and developing resistance, there is a need for understanding the mechanisms of resistance as well as its clinical impact while…”
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Alcohols are inhibitors of Saccharomyces cerevisiae multidrug-resistance pumps Pdr5p and Snq2p by Gášková, Dana, Plášek, Jaromír, Zahumenský, Jakub, Benešová, Ivana, Buriánková, Ľuboslava, Sigler, Karel

“…Abstract The effect of alcohols on cell membrane proteins has originally been assumed to be mediated by their primary action on membrane lipid matrix. Many…”
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Enhanced Sensitivity of pHluorin-Based Monitoring of Intracellular pH Changes Achieved through Synchronously Scanned Fluorescence Spectra by Plasek, Jaromir, Melcrova, Adela, Gaskova, Dana

“…Since its introduction in 1998, genetically encoded pH-sensitive sensor ratiometric pHluorin proved to be a valuable tool for cell physiology studies. Here, we…”
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C. elegans longevity pathways converge to decrease mitochondrial membrane potential by Lemire, Bernard D., Behrendt, Maciej, DeCorby, Adrienne, Gášková, Dana

“…Energy production via oxidative phosphorylation generates a mitochondrial membrane potential (Δ Ψ m) across the inner membrane. In this work, we show that a…”
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Impact of Farnesol as a Modulator of Efflux Pumps in a Fluconazole-Resistant Strain of Candida albicans by Černáková, Lucia, Dižová, Stanislava, Gášková, Dana, Jančíková, Iva, Bujdáková, Helena

“…This work studied the impact of the quorum-sensing molecule, farnesol (FAR), on fluconazole (FLC)-resistant isolate CY 1123 compared with the susceptible…”
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Differences in the arrangement of the Pdr5p multidrug transporter binding pocket of Saccharomyces cerevisiae and Kluyveromyces lactis by Jancíková, Iva, Zahumenský, Jakub, Gbelská, Yvetta, Gášková, Dana

“…Multidrug transporters are often responsible for failure of medical treatment, since they expel a variety of structurally and functionally unrelated drugs out…”
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Early changes in membrane potential of Saccharomyces cerevisiae induced by varying extracellular K+, Na+ or H+ concentrations by Plášek, Jaromír, Gášková, Dana, Ludwig, Jost, Höfer, Milan

“…Recently we introduced a fluorescent probe technique that makes possible to convert changes of equilibrium fluorescence spectra of…”
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A method for determining supernatant-free spectra generated from fluorescently stained cells in suspension by Plášek, Jaromír, Gášková, Dana

“…[Display omitted] •We present a cuvette holder for the front-face fluorometry of pelleted cell layers.•Supernatant-free fluorescence spectra of cells in…”
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Characterization of the kinetics and mechanisms of inhibition of drugs interacting with the S. cerevisiae multidrug resistance pumps Pdr5p and Snq2p by Hendrych, Tomáš, Kodedová, Marie, Sigler, Karel, Gášková, Dana

“…We have developed a novel screening method that measures the kinetics and potencies of inhibitors of the yeast multidrug resistance pumps Pdr5p and Snq2p. The…”
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Fluorescence method for determining the mechanism and speed of action of surface-active drugs on yeast cells by Kodedová, Marie, Sigler, Karel, Lemire, Bernard D, Gášková, Dana

“…New antifungal agents are needed to treat life-threatening fungal infections, particularly with the development of resistance. Surface-active antifungals have…”
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Expression of Ndi1p, an alternative NADH:ubiquinone oxidoreductase, increases mitochondrial membrane potential in a C. elegans model of mitochondrial disease by DeCorby, Adrienne, Gášková, Dana, Sayles, Leanne C., Lemire, Bernard D.

“…The NADH:ubiquinone oxidoreductase or complex I of the mitochondrial respiratory chain is an intricate enzyme with a vital role in energy metabolism. Mutations…”
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Complementary Methods of Processing diS-C sub(3)(3) Fluorescence Spectra Used for Monitoring the Plasma Membrane Potential of Yeast: Their Pros and Cons by Plasek, Jaromir, Gaskova, Dana

“…Carbocyanine dye diS-C sub(3)(3) was repeatedly employed in monitoring the plasma membrane potential of yeast and other living cells. Four methods of measuring…”
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Chemosensitization of multidrug resistant Candida albicans by the oxathiolone fused chalcone derivatives by Ła̧cka, Izabela, Konieczny, Marek T, Bułakowska, Anita, Kodedová, Marie, Gašková, Dana, Maurya, Indresh K, Prasad, Rajendra, Milewski, Sławomir

“…Three structurally related oxathiolone fused chalcone derivatives appeared effective chemosensitizers, able to restore in part sensitivity to fluconazole of…”
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DiS-C 3(3) monitoring of in vivo mitochondrial membrane potential in C. elegans by Gášková, Dana, DeCorby, Adrienne, Lemire, Bernard D.

“…The mitochondrial respiratory chain plays a crucial role in cellular and organismal health. In addition to being the major source of energy for most cells,…”
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DiS-C3(3) monitoring of in vivo mitochondrial membrane potential in C. elegans by Gásková, Dana, DeCorby, Adrienne, Lemire, Bernard D

“…The mitochondrial respiratory chain plays a crucial role in cellular and organismal health. In addition to being the major source of energy for most cells,…”
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Fluorescence Emission Spectra of Calcofluor Stained Yeast Cell Suspensions: Heuristic Assessment of Basis Spectra for their Linear Unmixing by Plášek, Jaromír, Dostál, Marek, Gášková, Dana

“…Fluorescence emission spectra of yeast cell suspensions stained with calcofluor have recently been identified as promising markers of variations in the quality…”
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Synchronous plasma membrane electrochemical potential oscillations during yeast colony development and aging by Palková, Zdena, Váchová, Libuse, Gásková, Dana, Kucerová, Helena

“…Microorganisms that survive in natural environments form organized multicellular communities, biofilms and colonies with specific properties. During stress and…”
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